Abstract:
INTRODUCTION:Controlled ovarian stimulation (COS) with intrauterine insemination (IUI) is an effective treatment in cases of cervical factor, unexplained infertility and mild male factor. The optimal timing of IUI after human chorionic gonadotrophin (hCG) after COS with clomiphene citrate is debatable and may be a factor limiting success of same. This study was designed to scientifically determine if variation in the timing of IUI could affect the cycle outcome. MATERIALS AND METHODS:In a prospective randomized trial couples with mild male factor, unexplained infertility and mild endometriosis who underwent COS with IUI were recruited. COS was achieved with clomiphene citrate. Two hundred and four women underwent 461 cycles of IUI. Women were randomized to two groups: group I (104 patients, 231 cycles) had IUI 36 h after hCG, while group II (100 patients, 230 cycles) had IUI 24 h after hCG. Primary outcome included pregnancy rate per couple and per cycle. RESULTS:Fifty-four patients had pregnancy with and pregnancy rate per couple and per cycle were 32.6 and 14.7% in group I and 20 and 8.6% in group II, respectively (not statistically different). CONCLUSIONS:Altering timing of IUI after COS does not enhance pregnancy rates. IUI 36 h after hCG has marginally better pregnancy rates than 24 h. Timing of insemination may be kept at 24 or 36 h after hCG injection to suit the convenience of the clinic or care provider. The lack of statistical significance indicates need for larger studies to draw guidelines.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Rahman SM,Karmakar D,Malhotra N,Kumar Sdoi
10.1007/s00404-011-1950-6subject
Has Abstractpub_date
2011-10-01 00:00:00pages
1023-7issue
4eissn
0932-0067issn
1432-0711journal_volume
284pub_type
杂志文章,随机对照试验abstract:CONTEXT:The deletion of the short arm of the chromosome 13, also known as 13q syndrome, is an extremely rare chromosomal disorder. Clinical manifestations include retinoblastoma, brain anomalies, mental and growth retardation, as well as renal, cardiac, gastrointestinal, facial, lip and digital defects. Antenatal diagn...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-006-0128-0
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:This study aimed at improving fertility rates among infertile women with poor ovarian reserve. METHODS:This was a randomized clinical trial conducted in the outpatient clinic of a tertiary hospital. We recruited infertile women with poor ovarian reserve. The study population was divided into 2 groups, each o...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-020-05603-5
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to investigate differential expression of the cell cycle signaling proteins p27 and Jun activation domain-binding protein 1 (Jab1) in benign ovarian cysts of patients with endometriosis compared to controls. METHODS:Ovarian tissues of 26 endometriosis and 28 non-endometriosis patie...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-015-3642-0
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:The systemic inflammatory response markers have been reported to be associated with the prognosis of various cancers. We conducted this meta-analysis of retrospective studies to evaluate and identify the prognostic impact of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) on ovarian ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00404-018-4678-8
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVE:The ultimate goal of this study is to reassess the five-dimensional implantation markers and pregnancy predictors on the day of human chorionic gonadotropin injection in the intracytoplasmic sperm injection and embryo transfer programs. DESIGN:A pilot prospective clinical trial. SETTING:The Assisted Reprodu...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-5001-4
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To calculate the measurement error of the hourly fetal urine production rate (HFUPR) and evaluate the implication of different methods for measuring the HFUPR, i.e. ellipsoid versus sum-of-cylinders method. METHODS:The calculation was based on sonographic documentation of the increased bladder volumes during t...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1242-6
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:There is an ongoing debate whether the source of sperm cells, the etiology or the extent of male factor infertility has influence on the outcome of ICSI cycles. METHODS:The results of intracytoplasmic sperm injection (ICSI) according to the source of spermatozoa in patients with severe male factor infertility ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-014-3448-5
更新日期:2015-03-01 00:00:00
abstract::Hypertensive disorders of pregnancy are associated with an increased risk of maternal and fetal morbidity and mortality. The cause and the pathogenesis of the pregnancy-induced syndrome, preeclampsia, is still poorly understood. Published evidence of altered biomarkers for the endothelial dysfunction suggests that the...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-010-1538-6
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:Acute fatty liver (AFL) of pregnancy is a difficult and challenging diagnosis. The treatment plan is usually supportive. CASE REPORT:We present a case of a patient with AFL of pregnancy and Gram-negative endomyometritis and sepsis. Our treatment plan included the use of activated protein C (APC). CONCLUS...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-004-0716-9
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:Mastectomy without axillary dissection should be the standard treatment in patients with malignant form of cystosarcoma phyllodes. The role of postoperative radiotherapy and chemotherapy remains to be fully established. We evaluate treatment results in a group of patients with cystosarcoma phyllodes (CP) treate...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-003-0593-7
更新日期:2004-05-01 00:00:00
abstract::In the original publication, the university name of the authors in the affiliations was published as University of Medical Sciences, Sabzevar, Iran. The correct university name should read as Sabzevar University of Medical Sciences, Sabzevar, Iran. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 已发布勘误
doi:10.1007/s00404-018-4986-z
更新日期:2019-02-01 00:00:00
abstract::The aim of this prospective, multicenter, randomized, case-control study was to investigate the efficacy of a nonspecific mucosal antiseptic (octenidine dihydrochloride, phenoxyethanol) with proven antifungal effects, in patients with acute symptomatic vaginal candidosis, in comparison with a specific topical antifung...
journal_title:Archives of gynecology and obstetrics
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/s00404-002-0368-6
更新日期:2003-08-01 00:00:00
abstract::Ultrasonic findings in 1317 operatively confirmed gynecological tumors were classified according to five degrees of homogeneity: I, clearly outlined solitary cysts; II, clearly outlined homogeneous tumors; III, poorly defined or slightly heterogeneous tumors; IV, marked heterogeneous tumors; V, completely heterogeneou...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF02417449
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:Τo estimate the discrepancy rate between colposcopy, punch biopsy histology and surgical specimen histology as well as the positive (PPV) and negative predictive value (NPV) of colposcopic diagnosis for high-grade squamous intraepithelial lesions (HGSIL). METHODS:A prospective study was conducted during the pe...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-018-4714-8
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:Ovarian hyperstimulation syndrome (OHSS) is a serious complication of assisted reproductive technology (ART) treatment. However, there are limited data regarding the ability of the luteal GnRH antagonist cetrorelix to reduce the incidence of moderate and severe OHSS, and the mechanism remains unclear. Thus, we ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05163-3
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Ovarian pregnancy (OP) is a rare form of ectopic pregnancy and is still a medical challenge. Therefore, more studies about the time trends, risk factors and diagnostic measurements are needed for the efficient treatment of OP. METHODS:The datum of OP patients who were treated at the Second Hospital of Hebei...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05648-6
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Although puerperal mastitis is a common disease, published data are poor. Increasing rates of community-acquired MRSA (CA-MRSA) cases are reported in the USA. However, information about common pathogens and CA-MRSA in Germany is still insufficient. The aim of this study was to investigate the most common pathog...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-019-05333-3
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the phosphorylated isoform of insulin-like growth factor binding protein-1 (phIGFBP-1) in endocervical secretions as a predictor of preterm delivery in symptomatic and asymptomatic pregnant women. METHODS:The study included 105 patients between 24 and 34 weeks' gestatio...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-008-0703-7
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Giant myomas of the uterus are uncommon, particularly in developed countries. CASE:This report illustrates a case of a woman with a bilobated giant myoma of the uterus weighed in total 27.7 kg. The patient had an abdominal distension first noted 18 months before and the personal history evidenced difficulti...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-007-0523-1
更新日期:2008-07-01 00:00:00
abstract:UNLABELLED:We describe two cases with persistent ascites after ovarian hyperstimulation syndrome (OHSS). Mifepristone (RU 486), an anti-progestin was administered to terminate pregnancy in both cases. DISCUSSION:To our knowledge, this is the first such report and we discuss the implications. ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-003-0477-x
更新日期:2003-04-01 00:00:00
abstract:PURPOSE:Sirenomelia is caused by atrophy of the lower extremities that is commonly associated with gastrointestinal and urogenital malformations. METHODS:Embryogenic environmental theories and systematic review of the literature are reported. RESULTS:Genetic basis of the condition has been demonstrated in the animal ...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,评审
doi:10.1007/s00404-013-2847-3
更新日期:2013-07-01 00:00:00
abstract::Serum levels of CA 125 were determined in 239 patients suffering from gynecological malignancies. The upper limit for normal was 35 U/ml. Raised levels were found in 82% of patients with primary ovarian carcinoma, and in 29% of those with benign ovarian tumors. The values from patients with ovarian carcinomas in parti...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/BF00931312
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Recent studies show that contrast-enhanced ultrasonography (CEUS) using SonoVue has the potential to improve the performance of sentinel lymph node biopsy (SLNB) in patients with early breast cancer. However, the evidence of SLNB using CEUS in patients converting from cN1 to cN0 after neoadjuvant chemotherap...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-020-05646-8
更新日期:2020-09-01 00:00:00
abstract:CASE REPORT:We report a case of an ectopic pregnancy in a caesarean section scar, which was initially misdiagnosed despite using ultrasound. For the first time, a strongly vascularised pelvic tumour developed while the titre of serum human chorionic gonadotrophin decreased after a curettage abortion for an unwanted pre...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-004-0683-1
更新日期:2005-02-01 00:00:00
abstract:INTRODUCTION:Carcinosarcomas of the uterine cervix are very rare. Most of them have a homologous mesenchymal component, and cervical carcinosarcomas with a heterologous mesenchymal component are limited to nine cases. CASE REPORT:A 61-year-old Japanese woman was admitted to the hospital for treatment of a ureteral sto...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-009-1017-0
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:The quality of life in postmenopause is seriously affected by the symptoms related to vaginal atrophy. To evaluate in a 3-month, prospective, randomized, double blind, study whether vaginal suppositories containing genistein might improve genital symptoms, colposcopical and cytologic findings or modify DNA cyto...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00404-010-1545-7
更新日期:2011-06-01 00:00:00
abstract::Pelvic floor protection is an issue of increasing relevance. This article sought to summarize the session at last year's annual meeting of the German Society of Gynecology and Obstetrics (DGGG) in Stuttgart (10/2016) called "Urogynecology 2020-what is the optimal rate of cesarean section-does urogynecology have to dea...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-017-4316-x
更新日期:2017-04-01 00:00:00
abstract::We have examined the predictive value of measurements of CASA (Cancer Associated Serum Antigen) levels in patients with breast carcinoma. The measurement uses monoclonal antibodies that bind to an epitope on the polymorphic epithelial mucin. CASA levels were of less value compared with the levels of other tumor marker...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s004040050215
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:Preeclampsia is one of the leading causes of maternal and perinatal morbidity and mortality. Till date despite years of research into the condition, predicting the onset of preeclampsia remains a problem. Placental growth factor is one of the many angiogenic factors, which shows significant altered levels in pr...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-011-1960-4
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:Our objective was to evaluate the outcome of vaginal removal of prolapsed pedunculated submucous myomas over a 10-year period. STUDY DESIGN:Retrospective observational study. Fifty-two patients were admitted with the diagnosis of prolapsed pedunculated submucous myoma. Six patients were excluded because of a...
journal_title:Archives of gynecology and obstetrics
pub_type: 杂志文章
doi:10.1007/s00404-003-0590-x
更新日期:2005-01-01 00:00:00