Abstract：
BACKGROUND:The aim of this study was to evaluate the phosphorylated isoform of insulin-like growth factor binding protein-1 (phIGFBP-1) in endocervical secretions as a predictor of preterm delivery in symptomatic and asymptomatic pregnant women. METHODS:The study included 105 patients between 24 and 34 weeks' gestation with uterine contractions and 73 controls. Ph IGFBP-1 in cervical secretions was assessed in all patients by using a qualitative, immunochromatographic one-step dipstick test. Data analysis included Student's test, Chi-Square, Fisher's exact test and Kruskal Wallis variance analysis. RESULTS:Preterm birth rate was 19.04% (20/105) in the study group. Of the 25 patients with a positive phIGFBP-1 test, mean gestational age at delivery was 32.8+/-3.8, whereas of the 80 patients with a negative phIGFBP-1 test mean gestational age at delivery was 37.8+/-2.5, in the study group (P<0.05). The sensitivity, specificity, positive predictive value and negative predictive value for phIGFBP-1 in symptomatic patients were 70, 87.05, 56 and 92.5%, respectively, while in asymptomatic patients they were 40, 82.35, 14.28 and 94.91%, respectively. CONCLUSIONS:The phIGFBP-1 in cervical secretions is a potential specific marker for preterm delivery occurring before 37 weeks. Also cervical detection of phIGFBP-1 by immunochromatography is a rapid and easily applicable test that highly predicts preterm delivery.
journal_name
Arch Gynecol Obstetjournal_title
Archives of gynecology and obstetricsauthors
Altinkaya O,Gungor T,Ozat M,Danisman N,Mollamahmutoglu Ldoi
10.1007/s00404-008-0703-7subject
Has Abstractpub_date
2009-03-01 00:00:00pages
279-83issue
3eissn
0932-0067issn
1432-0711journal_volume
279pub_type
杂志文章abstract：:To compare the safety and efficacy of two different regimens of misoprostol for labor induction at term, we conducted a randomized controlled trial on women presenting for induction of labor at > or =37 weeks' gestation. Eligible women were randomized to receive intravaginal misoprostol 50 microg every 4 h or 100 micr...
journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章,随机对照试验
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abstract：:We report the case of a 66-year-old woman who had a hysterectomy because of uterine tumour. Histological examination showed a leiomyoma with degenerative changes and extensive extramedullary haematopoiesis. There was no evidence of any haematological or systemic disease. Extramedullary haematopoiesis in patients witho...
journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章,随机对照试验
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abstract：OBJECTIVE:To estimate prevalence of malignancy and dysplasia in cervical polyps and to judge whether cervical polyps need to be removed routinely. Also to investigate if a cervical polyp is an indicator of endometrial pathology and to assess the necessity of performing dilatation and curettage (D&C). MATERIALS AND MET...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
pub_type： 临床试验,杂志文章
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,评审
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更新日期：2009-08-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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更新日期：2012-02-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
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abstract：OBJECTIVES:To compare the diagnostic accuracy of brush endometrial sampling with conventional dilatation and curettage in women with abnormal uterine bleeding. PATIENTS AND METHODS:Two hundred and twenty (220) women with abnormal uterine bleeding were included in this comparative study; endometrial sampling was done b...
journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
pub_type： 信件
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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更新日期：2011-12-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
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更新日期：2019-10-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
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更新日期：2006-06-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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更新日期：2018-11-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
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更新日期：1996-01-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章,随机对照试验
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journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/s00404-019-05236-3
更新日期：2019-09-01 00:00:00
abstract：:We report a case of repeated fetal death at 31 gestational weeks associated with mild non-proteinuric pre-eclampsia and intrauterine growth retardation. After double intradermal immunisation with paternal leukocytes, a third pregnancy proceeded uneventfully until it ended at 38 weeks. Maternal anti-paternal blocking a...
journal_title：Archives of gynecology and obstetrics
pub_type： 杂志文章
doi：10.1007/BF02389636
更新日期：1992-01-01 00:00:00
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journal_title：Archives of gynecology and obstetrics
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更新日期：2012-12-01 00:00:00
