Uterine cervical carcinosarcoma with heterologous mesenchymal component: a case report and review of the literature.

Abstract:

INTRODUCTION:Carcinosarcomas of the uterine cervix are very rare. Most of them have a homologous mesenchymal component, and cervical carcinosarcomas with a heterologous mesenchymal component are limited to nine cases. CASE REPORT:A 61-year-old Japanese woman was admitted to the hospital for treatment of a ureteral stone. Imaging studies detected an indistinct cervical mass. A histopathological diagnosis of the cervical biopsy was a carcinosarcoma. A total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy was carried out upon a diagnosis of stage Ib1 cervical carcinosarcoma. Microscopically, the cervical mass revealed a carcinosarcoma consisting of endometrioid adenocarcinoma and chondrosarcoma. Immunohistochemically, p53 was positive in the epithelial and mesenchymal components. Postoperatively, the patient underwent radiation and chemotherapy. She is alive with no evidence of recurrence 5 years and 10 months after the operation. CONCLUSION:We suppose that the similar proportion of p53 overexpression in both the epithelial and mesenchymal components may be one of the findings explaining the histogenesis of this tumor by combination theory.

journal_name

Arch Gynecol Obstet

authors

Kadota K,Haba R,Ishikawa M,Kushida Y,Katsuki N,Hayashi T,Miyai Y,Bando K,Shiota A,Hata T

doi

10.1007/s00404-009-1017-0

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

839-43

issue

5

eissn

0932-0067

issn

1432-0711

journal_volume

280

pub_type

杂志文章
  • Downregulation of miR-4443 and miR-5195-3p in ovarian cancer tissue contributes to metastasis and tumorigenesis.

    abstract:BACKGROUND AND PURPOSE:Ovarian cancer (OC) is one of the most fatal malignancies in women. High mortality rate may be due to problems with diagnosis in the early stages. The use of new biomarkers for faster diagnosis and selection of more efficient therapies is one of the main concerns in this area. miRNAs are non-codi...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-019-05107-x

    authors: Ebrahimi SO,Reiisi S

    更新日期:2019-05-01 00:00:00

  • Reducing the spread of occult uterine sarcoma at the time of minimally invasive gynecologic surgery.

    abstract:PURPOSE:This review covers the most recent evidence to discuss the incidence of occult uterine sarcoma, whether morcellation increases tumor dissemination or mortality, and whether there is a difference between different types of morcellation. We will also discuss techniques to reduce the spread of an undiagnosed uteri...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-017-4575-6

    authors: Wong M,De Wilde RL,Isaacson K

    更新日期:2018-02-01 00:00:00

  • Complications of vaginal hysterectomy under "difficult" circumstances.

    abstract::Vaginal hysterectomy is less invasive than hysterectomy performed via the abdominal approach. The vaginal approach may be made difficult by prior conisation, a need to remove the adnexae or marked uterine enlargement requiring morcellement. In this retrospective study we have investigated the impact of these factors o...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF02390389

    authors: Gitsch G,Berger E,Tatra G

    更新日期:1991-01-01 00:00:00

  • Effects of tamoxifen on human breast cancer cells in vitro.

    abstract::Long-term treatment of the estrogen sensitive human breast cancer cell line EFM-19 with the antiestrogenic compound Tamoxifen resulted in a variant line EFM-19 T, which was stimulated by Tamoxifen. Estrogen receptor analysis by radioligand assay (charcoal method), revealed a 2.5 fold higher receptor concentration in E...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/BF02767330

    authors: Simon WE,Trams G,Hölzel F

    更新日期:1993-01-01 00:00:00

  • Effect of myocardial infarction on female sexual function in women.

    abstract:PURPOSE:The aim of this study was to assess sexual function in female patients with myocardial infarction (MI). METHODS:As research instruments, an interview form of 20 questions that questioned personal characteristics was developed by researchers, Female Sexual Function Index (FSFI) that evaluated sexual dysfunction...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-014-3537-5

    authors: Oskay U,Can G,Camcı G

    更新日期:2015-05-01 00:00:00

  • Detection of E6-AP as a potential therapeutic target in cervical specimen of HPV-infected women.

    abstract:PURPOSE:Silencing of HPV oncogenes or their human host client proteins using topically applied small interfering RNA (siRNA) may be an attractive nonsurgical strategy for CIN treatment. An exploratory clinical investigation was designed to evaluate E6-AP mRNA expression levels in different stages of cervical intraepith...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-013-3120-5

    authors: Hillemanns P,Jentschke M,Evans TG,Soergel P,Hass R

    更新日期:2014-06-01 00:00:00

  • Retention of cervical cerclage after preterm premature rupture of the membranes: a critical appraisal.

    abstract:PURPOSE:The present meta-analysis aims to assess the efficacy of cervical cerclage retention after the occurrence of preterm premature rupture of the membranes by analyzing the observed maternal and neonatal perinatal outcomes. METHODS:We searched Medline (1966-2014), Scopus (2004-2014), Clinicaltrials.org (1997-2014)...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-014-3551-7

    authors: Pergialiotis V,Gkioka E,Bakoyiannis I,Mastroleon I,Prodromidou A,Perrea D

    更新日期:2015-04-01 00:00:00

  • Morphological evaluation of lateral ventricles of fetuses with ventriculomegaly by three-dimensional ultrasonography and magnetic resonance imaging: correlation with etiology.

    abstract:PURPOSE:To evaluate morphology of lateral ventricles of ventriculomegaly/hydrocephaly fetuses using 3D-sonography by virtual organ computer-aided analysis (VOCAL) technique and magnetic resonance imaging (MRI) and verify morphologic patterns related to etiology. METHODS:Seventeen fetuses presenting with ventricular en...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-010-1666-z

    authors: Haratz KK,Nardozza LM,de Oliveira PS,Rolo LC,Milani HJ,de Sá Barreto EQ,Araujo Júnior E,Ajzen SA,Moron AF

    更新日期:2011-08-01 00:00:00

  • Estimation of neonatal outcome artery pH value according to CTG interpretation of the last 60 min before delivery: a retrospective study. Can the outcome pH value be predicted?

    abstract:PURPOSE:The aim of this study was to analyze whether the umbilical artery pH value can be estimated throughout CTG assessment 60 min prior to delivery and if the estimated umbilical artery pH value correlates with the actual one. This includes analysis of correlation between CTG trace classification and actual umbilica...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-017-4516-4

    authors: Kundu S,Kuehnle E,Schippert C,von Ehr J,Hillemanns P,Staboulidou I

    更新日期:2017-11-01 00:00:00

  • Functional interactions between the fossa ischioanalis, levator ani and gluteus maximus muscles of the female pelvic floor: a prospective study in nulliparous women.

    abstract:PURPOSE:We evaluated the role of the fossa ischioanalis (FI) in functional relations between the levator ani (LA) and gluteus maximus muscles (GM) in healthy female volunteers. METHODS:Twenty-three nulliparae were examined. Electromyogramms of LA and GM were simultaneously recorded during voluntary contraction of the ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-012-2377-4

    authors: Soljanik I,Janssen U,May F,Fritsch H,Stief CG,Weissenbacher ER,Friese K,Lienemann A

    更新日期:2012-10-01 00:00:00

  • Effect of lesion location on endometriotic adhesion and angiogenesis in SCID mice.

    abstract:OBJECTIVE:To evaluate the effects of lesion location on adhesion and angiogenesis of transplanted endometriotic lesions in SCID mice. METHODS:Three groups of female SCID mice included intraperitoneal (i.p.) (n = 12), subcutaneous (s.c.) (n = 12), and mock surgery (control) (n = 12). At 2 weeks after ovariectomy, the m...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-013-3048-9

    authors: Lu Z,Zhang W,Jiang S,Zou J,Li Y

    更新日期:2014-04-01 00:00:00

  • Determinants of cumulative ART live-birth rates in a single-center study: age, fertilization modality, and first-cycle outcome.

    abstract:PURPOSE:To analyze cumulative and single-cycle success rates of IVF and intracytoplasmic sperm injection (ICSI) separately in relation to female age, fertilization modality, and first-cycle outcome. METHODS:The study involved 2997 patients and couples, respectively, who underwent 5339 fresh and 3006 cryo cycles using ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-016-4162-2

    authors: Tigges J,Godehardt E,Soepenberg T,Maxrath B,Friol K,Gnoth C

    更新日期:2016-11-01 00:00:00

  • Old and novel insights into emergency peripartum hysterectomy: a time-trend analysis.

    abstract:PURPOSE:To assess changing trends, role of the triad patient-pregnancy-health professionals and health care cost in emergency peripartum hysterectomy (EPH). METHODS:Demographics, indications, perinatal outcomes, perioperative complications in EPH cases performed in a 10-year period were extracted from the local birth ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-020-05504-7

    authors: Triunfo S,Ferrazzani S,Volpe M,Scambia G,Lanzone A

    更新日期:2020-05-01 00:00:00

  • The incidence of complications by hysterectomy for benign disease in correlation to an assumed preoperative score.

    abstract:BACKGROUND:Hysterectomies are preformed abdominally, vaginally, laparoscopic or with robotic assistance. When choosing the route of hysterectomy, the physician should take into consideration the safest and most cost-effective route to fulfill all needs of the patient. METHODS:Data were collected retrospectively from 9...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-014-3594-9

    authors: Elessawy M,Schollmeyer T,Mettler L,Jonat W,Schem C,von Hehn U,Alkatout I

    更新日期:2015-07-01 00:00:00

  • An invisible stenotic cervix.

    abstract:INTRODUCTION:Conization of the uterine cervix is a common gynecological procedure that sometimes causes cervical stenosis which creates difficulties for future gynecological procedures. MATERIAL:We present a very unusual case where strenuous effort was needed to obtain safe access to the endocervical canal and endomet...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-010-1832-3

    authors: Walid MS,Heaton RL

    更新日期:2011-03-01 00:00:00

  • A prospective randomised study of total laparoscopic hysterectomy, laparoscopically assisted vaginal hysterectomy and non-descent vaginal hysterectomy for the treatment of benign diseases of the uterus.

    abstract:AIMS AND OBJECTIVES:To compare the three techniques of hysterectomy-total laparoscopic hysterectomy (TLH), laparoscopic assisted vaginal hysterectomy (LAVH) and non-descent vaginal hysterectomy (NDVH). MATERIALS AND METHODS:Ninety women with benign disease of uterus with failed medical management or not amenable to me...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00404-010-1778-5

    authors: Roy KK,Goyal M,Singla S,Sharma JB,Malhotra N,Kumar S

    更新日期:2011-10-01 00:00:00

  • The fertility and pregnancy outcomes of the patients who underwent preservative operation followed by adjuvant chemotherapy for malignant ovarian tumors.

    abstract::The fertility and pregnancy outcomes of the patients were studied, who previously underwent preservative operation for malignant tumors, including those of borderline malignancy, in our ward from 1981 to 1995. For each of the 9 patients, unilateral ovary was preserved, the range of their ages before operation was 10 t...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s004040000094

    authors: Yoshinaka A,Fukasawa I,Sakamoto T,Tanaka M,Ota Y,Inaba N

    更新日期:2000-11-01 00:00:00

  • Human papillomavirus DNA, HPV L1 capsid protein and p16INK4a protein as markers to predict cervical lesion progression.

    abstract:OBJECTIVES:Cervical cancer is the most common malignant tumors in women leading to serious morbidity and mortality worldwide, especially among developing countries. A main cause of the disease is the high-risk human papillomavirus (HR-HPV) infection. HSIL usually progress to cervical cancer, and low-grade lesions, incl...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-018-4931-1

    authors: Hu H,Zhao J,Yu W,Zhao J,Wang Z,Jin L,Yu Y,Han L,Wang L,Zhu H,Li F

    更新日期:2019-01-01 00:00:00

  • Effect of Chlamydia trachomatis on adverse pregnancy outcomes: a meta-analysis.

    abstract:PURPOSE:To analyze the effect of Chlamydia trachomatis (C. trachomatis) on adverse pregnancy outcomes based on the currently available evidence. METHODS:Multiple databases were comprehensively searched from the available date of inception through December 9, 2019. The effect of C. trachomatis on adverse pregnancy outc...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00404-020-05664-6

    authors: He W,Jin Y,Zhu H,Zheng Y,Qian J

    更新日期:2020-09-01 00:00:00

  • Anti-Mullerian Hormone: an indicator for the severity of polycystic ovarian syndrome.

    abstract:PURPOSE:Features of polycystic ovarian syndrome (PCOS) including sonographic aspects, androgens, LH and LH/FSH ratio as well as Anti-Mullerian Hormone (AMH) were evaluated according to their diagnostic potency in detecting different degrees of PCOS severity. METHODS:80 women with PCOS diagnosed according to the Rotter...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-014-3317-2

    authors: Köninger A,Koch L,Edimiris P,Enekwe A,Nagarajah J,Kasimir-Bauer S,Kimmig R,Strowitzki T,Schmidt B

    更新日期:2014-11-01 00:00:00

  • New trial of progestin-primed ovarian stimulation using dydrogesterone versus a typical GnRH antagonist regimen in assisted reproductive technology.

    abstract:PURPOSE:To compare the clinical and ongoing pregnancy rates between a protocol using oral dydrogesterone with human menopausal gonadotropin (HMG) for progestin-primed ovarian stimulation (PPOS) and the typical gonadotropin-releasing hormone (GnRH) antagonist regimen in women undergoing controlled ovarian hyperstimulati...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-018-4856-8

    authors: Iwami N,Kawamata M,Ozawa N,Yamamoto T,Watanabe E,Moriwaka O,Kamiya H

    更新日期:2018-09-01 00:00:00

  • High mean platelet volume, low-grade systemic coagulation and fibrinolytic activation are associated with androgen and insulin levels in polycystic ovary syndrome.

    abstract:OBJECTIVES:The present study was designed to determine (a) the coagulation parameters, WBC and MPV levels; (b) whether there was any association between androgen and mean platelet volume and low-grade systemic coagulation in PCOS patients. METHODS:A total of 48 patients with non-diabetic PCOS were studied in order to ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-008-0884-0

    authors: Kebapcilar L,Taner CE,Kebapcilar AG,Sari I

    更新日期:2009-08-01 00:00:00

  • Delayed cord clamping does not affect umbilical cord blood gas analysis.

    abstract:BACKGROUND:Although delayed umbilical cord clamping has been shown to have significant benefits for both term and preterm infants, currently, data on its impact on blood gas analysis have been scant and conflicting. METHODS:In a retrospective review, we compared the demographic characteristics and blood gas parameters...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-019-05048-5

    authors: Tang J,Fullarton R,Samson SL,Chen Y

    更新日期:2019-03-01 00:00:00

  • The effect of dexpanthenol on experimentally induced ovarian ischaemia/reperfusion injury: a biochemical and histopathological evaluation.

    abstract:OBJECTIVE:The aim of this study was to evaluate the effect of two different doses of dexpanthenol (Dxp) onexperimentally induced ovarian ischaemia/reperfusion (I/R) injury ina rat model. STUDY DESIGN:Forty female rats were randomly divided into fivegroups: Group 1: sham operation; Group 2: 3-h ischaemia; Groups 3: 3-h...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-017-4287-y

    authors: Soylu Karapinar O,Pinar N,Özcan O,Atik Doğan E,Bayraktar S,Şahin H,Dolapçioğlu K

    更新日期:2017-03-01 00:00:00

  • Retained foetal bones: an intrauterine cause of chronic pelvic pain.

    abstract::Intrauterine retention of foetal bones is an uncommon but recognised complication of late termination of pregnancy. Secondary subfertility, abnormal uterine bleeding and vaginal discharge are the usual presenting complaints. We report a case of prolonged retention of foetal bones for 14 years in a woman who presented ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-008-0686-4

    authors: Kalu E,Richardson R

    更新日期:2009-02-01 00:00:00

  • Identification of key genes associated with the effect of estrogen on ovarian cancer using microarray analysis.

    abstract:PURPOSE:To identify key genes related to the effect of estrogen on ovarian cancer. METHODS:Microarray data (GSE22600) were downloaded from Gene Expression Omnibus. Eight estrogen and seven placebo treatment samples were obtained using a 2 × 2 factorial designs, which contained 2 cell lines (PEO4 and 2008) and 2 treatm...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-015-3833-8

    authors: Zhang ST,Zuo C,Li WN,Fu XQ,Xing S,Zhang XP

    更新日期:2016-02-01 00:00:00

  • Factors predicting nodal metastasis in endometrial cancer.

    abstract:PURPOSE:Evaluation of lymph node (LN) metastases in endometrial carcinoma (EC) is an important prognostic factor and a required element of cancer staging. The purpose of this study is to analyze what factors might predict the likelihood of nodal involvement in EC. METHODS:A retrospective search of our institutional da...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-014-3330-5

    authors: Gilani S,Anderson I,Fathallah L,Mazzara P

    更新日期:2014-12-01 00:00:00

  • Obstructive nephropathy and chronic kidney disease secondary to uterine leiomyomas.

    abstract::We present three cases of chronic kidney disease secondary to large fibroid uterus. The difficulties experienced in their clinical management and a review of literature is outlined. ...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章,评审

    doi:10.1007/s00404-008-0769-2

    authors: Bansal T,Mehrotra P,Jayasena D,Okolo S,Yoong W,Govind A

    更新日期:2009-06-01 00:00:00

  • Normal nephrogenesis occurs in the early stage of bilateral multicystic dysplastic kidneys.

    abstract::We present a case report about bilateral multicystic dysplastic kidneys (MCDKs). Pregnancy was terminated at 21 weeks' gestation and the fetus was examined by autopsy. The kidneys were replaced by many cysts and there was no parenchyma. However, on histological examination, there was normal nephrogenesis amid the cyst...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s004040100188

    authors: Furuhashi M,Kawai H,Chaya J,Ishida T

    更新日期:2002-07-01 00:00:00

  • Prevalence and associated risk factors for gestational diabetes in Jos, North-central, Nigeria.

    abstract:OBJECTIVE:The study aimed at determining the prevalence and associated risk factors for gestational diabetes mellitus (GDM) among antenatal women attending the Jos University Teaching Hospital (JUTH), Jos, Nigeria. METHODS:A cross-sectional study was done between February and April 2009 among 265 pregnant women enroll...

    journal_title:Archives of gynecology and obstetrics

    pub_type: 杂志文章

    doi:10.1007/s00404-012-2649-z

    authors: Anzaku AS,Musa J

    更新日期:2013-05-01 00:00:00