The role of endogenous free radical scavengers on tissue recovery in the experimental ulcer model.

abstract：:A detailed history and examination removes much of the vagueness from the symptoms of irritable bowel syndrome patients. The syndrome is much more homogeneous than suggested by the patient's complaints. Detailed questioning and examination contribute to further information in over two-thirds of patients. Examination r...

journal_title：Journal of clinical gastroenterology

authors： Fielding JF

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Twenty-four-hour multichannel intraluminal impedance and pH (MII-pH) esophageal monitoring allows detection of both acid and nonacid gastroesophageal reflux episodes. The MII-pH catheter contains 6 impedance segments placed 3, 5, 7, 9, 15, and 17 cm above the lower esophageal sphincter (LES), plus a pH elect...

journal_title：Journal of clinical gastroenterology

authors： Hila A,Chowdhury N,Hajar N,Castell DO

更新日期：2011-11-01 00:00:00

abstract：GOAL:The goal of this study was to evaluate the safety of propofol when used by gastroenterologists in patients who have an inadequate response to standard sedation (narcotics and benzodiazepines). BACKGROUND:Many patients fail to achieve adequate sedation from narcotics and benzodiazepines during colonoscopy. The adm...

journal_title：Journal of clinical gastroenterology

authors： Okeke FC,Shaw S,Hunt KK,Korsten MA,Rosman AS

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Human enteric antimicrobial peptides composed predominantly of human enteric α-defensins (HD5 and HD6) are important in the mucosal antimicrobial barrier. Previous studies have identified that genetic variations at rs2066844, rs2066845, rs2066847 are associated with diminished enteric α-defensins in...

journal_title：Journal of clinical gastroenterology

authors： Deng Q,Tan G,Deng F,Zhi F

更新日期：2020-07-01 00:00:00

abstract：:Gastrointestinal (GI) disturbances are common during training and competition, especially among endurance athletes. Historically, little attention has been paid to the psychobiological etiology of GI problems in sport. The aim of this review is to: (1) provide a physiological overview of how psychological stress and a...

journal_title：Journal of clinical gastroenterology

authors： Wilson PB

更新日期：2020-04-01 00:00:00

abstract：GOALS:To test the hypothesis that water exchange (WE), when compared with carbon dioxide (CO2) insufflation, significantly reduces the right colon adenoma miss rate (rAMR) in a blinded randomized controlled trial with cap-assisted colonoscopy. BACKGROUND:The unblinded consecutive group observational data showed that W...

journal_title：Journal of clinical gastroenterology

authors： Cheng CL,Kuo YL,Hsieh YH,Tang JH,Leung FW

更新日期：2020-10-16 00:00:00

abstract：GOALS:To investigate the association between treatment nonadherence and patients' knowledge of the prescribed medication among individuals with inflammatory bowel disease (IBD), and evaluate the impact of nonadherence on relapse. BACKGROUND:The patient's knowledge of the prescribed medication has been identified as an...

journal_title：Journal of clinical gastroenterology

authors： Tae CH,Jung SA,Moon HS,Seo JA,Song HK,Moon CM,Kim SE,Shim KN,Jung HK

更新日期：2016-02-01 00:00:00

abstract：:Identical twins presented as sexagenarians with heartburn, regurgitation, and dysphagia; each had a Barrett esophagus remarkably similar to the other. This instance suggests a hereditary influence upon the development of mucosal dysplasia in some patients with this condition. ...

journal_title：Journal of clinical gastroenterology

authors： Gelfand MD

更新日期：1983-06-01 00:00:00

abstract：:To assess the effects of the mucoprotective drug sofalcone, which has direct and indirect effects on Helicobacter pylori in vitro, the eradication rate, adverse effects, and the quality of healing peptic ulcers were evaluated. Each study patient was given 500 mg t.i.d. amoxicillin and 200 mg t.i.d. clarithromycin. In ...

journal_title：Journal of clinical gastroenterology

authors： Sakaki N,Arakawa T,Kozawa H,Yamada Y,Kato H,Kamisawa T,Momma K

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/GOALS:Many patients with a history of injection drug use (IDU) are excluded from hepatitis C virus (HCV) treatment. This prospective multicenter study aimed to determine the impact of IDU history on HCV treatment candidacy and outcomes. STUDY:Between 1999 and 2001, 4318 HCV-infected patients seen at 24 VA M...

journal_title：Journal of clinical gastroenterology

authors： Seal KH,Currie SL,Shen H,Anand BS,Bini EJ,Brau N,Jeffers L,Wright TL,VA HCV-001 Study Group.

更新日期：2007-02-01 00:00:00

abstract：GOALS:The goal of this study was to examine the effect of a standardized silybin and soy phosphatidylcholine complex (IdB 1016) on serum markers of iron status. BACKGROUND:Milk thistle and its components are widely used as an alternative therapy for liver disease because of purported antioxidant, anti-inflammatory, an...

journal_title：Journal of clinical gastroenterology

authors： Bares JM,Berger J,Nelson JE,Messner DJ,Schildt S,Standish LJ,Kowdley KV

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:There has been constant speculation about the association between metabolic syndrome (MetS) and colorectal neoplasia (CN); however, the published results are conflicting. The aims of this study are to conduct a systematic search, and assess the literature to determine the available evidence on the associatio...

journal_title：Journal of clinical gastroenterology

authors： Jinjuvadia R,Lohia P,Jinjuvadia C,Montoya S,Liangpunsakul S

更新日期：2013-01-01 00:00:00

abstract：:A 45-year-old woman receiving continuous infusions of 5-fluoro-2'-deoxy-uridine into the hepatic artery through a surgically implanted intraarterial catheter for hepatic metastases from adenocarcinoma of the colon, developed acute epigastric pain and anemia. Endoscopy demonstrated a duodenal ulcer with a portion of th...

journal_title：Journal of clinical gastroenterology

authors： Hutchins LF,Webb RT,Ortego TJ,Lang NP,Navab F

更新日期：1988-08-01 00:00:00

abstract：:Sucralfate binds to duodenal and gastric ulcers and to gastric erosions produced by ethanol and anti-inflammatory drugs. The affinity of sucralfate for defective mucosa is explained by the drug's viscous adhesiveness and the formation of polyvalent bridges between the negatively charged sucralfate polyanions and posit...

journal_title：Journal of clinical gastroenterology

authors： Nagashima R

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:The cure for hepatitis B is defined as the hepatitis B surface antigen (HBsAg) seroclearance and/or seroconversion. Predictors of spontaneous seroconversion are not well described. The objective of this study is to identify predictors of spontaneous HBsAg seroconversion from community practice. METHODS:We p...

journal_title：Journal of clinical gastroenterology

authors： Wu CF,Fong TM,Wu SS,Saab S

更新日期：2020-07-01 00:00:00

abstract：:Silybum marianum (milk thistle) and its derivatives have been used for centuries for the treatment of liver disease. This review focuses exclusively on published literature pertaining to the potential use of Silybum marianum or its derivatives for the treatment of alcoholic liver disease. Clinical studies have varied ...

journal_title：Journal of clinical gastroenterology

authors： Ball KR,Kowdley KV

更新日期：2005-07-01 00:00:00

abstract：:Patients who are hepatitis B surface antigen (HBsAg) positive are at risk for hepatitis flare when receiving cytotoxic or immunosuppressive therapy. It has been reported that as high as 50% of HBsAg-positive individuals who undergo chemotherapy develop elevation of liver transaminases. According to current Association...

journal_title：Journal of clinical gastroenterology

authors： Wu JM,Huang YH,Lee PC,Lin HC,Lee SD

更新日期：2009-05-01 00:00:00

abstract：:This article emphasizes and reviews the premise that because the pathogenesis of acute gastric mucosal injury is multifactorial, several protective mechanisms should also be considered in analyzing gastric mucosal defense. The first part of the article reviews the pathogenesis of acute gastric mucosal injury by major ...

journal_title：Journal of clinical gastroenterology

authors： Szabo S

更新日期：1991-01-01 00:00:00

abstract：:We describe a 33-year-old man with giant hypertrophic gastropathy (Menetrier's disease), which, on operative biopsy of the stomach, showed a significant inflammatory component. The patient was treated with prednisone and quickly responded. Although a review of the literature revealed only two cases similarly treated, ...

journal_title：Journal of clinical gastroenterology

authors： Davis GE,O'Rourke MC,Metz JR,Kindig WV,Sweeney JG,Kane KN

更新日期：1991-08-01 00:00:00

abstract：:The benefit of early endoscopy in the management of peptic ulcer bleeding remains controversial. In this study we looked at the role of early endoscopy in bleeding peptic ulcer patients with clear, "coffee grounds," or bloody nasogastric aspirate. A consecutive series of 325 patients with peptic ulcer bleeding were in...

journal_title：Journal of clinical gastroenterology

authors： Lin HJ,Wang K,Perng CL,Chua RT,Lee FY,Lee CH,Lee SD

更新日期：1996-06-01 00:00:00

abstract：:Forty-five polyps were encountered at duodenoscopy between 1973 and 1978. Upper gastrointestinal x-rays were helpful in 25 patients, 13 of whom had duodenal polyps and 12 duodenal deformity or mass lesions. Polyps in 23 patients were larger than 1 cm in size. Biopsies were done in 38 patients; in 19 there was only nor...

journal_title：Journal of clinical gastroenterology

authors： Reddy RR,Schuman BM,Priest RJ

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Although of unproven benefit for nonalcoholic steatohepatitis (NASH), thiazolidinediones (TZDs) have emerged as a promising therapy. Little evidence exists, however, regarding sustained effects of TZDs in NASH after drug discontinuation. A recent clinical study suggests that relapse of NASH pathophysiology i...

journal_title：Journal of clinical gastroenterology

authors： Argo CK,Iezzoni JC,Al-Osaimi AM,Caldwell SH

更新日期：2009-07-01 00:00:00

abstract：AIM:To test the activities of culture-extracted or commercially available toll-like receptors (TLRs) ligands to establish their direct impact on target gastrointestinal motor cells. METHODS:Short-term and long-term effects of Shigella flexneri M90T and Escherichia coli K-2 strains-extracted lipopolysaccharides (LPS), ...

journal_title：Journal of clinical gastroenterology

authors： Tattoli I,Petitta C,Scirocco A,Ammoscato F,Cicenia A,Severi C

更新日期：2012-10-01 00:00:00

abstract：:A 53-year-old white woman developed diabetes mellitus, migratory erythema, and anemia, clinical features suggesting the presence of a "glucagonoma." Ten years earlier, after laparotomy and pancreatic biopsy, she had been told that she had an inoperable pancreatic carcinoma. Review of that biopsy together with current ...

journal_title：Journal of clinical gastroenterology

authors： Pitchumoni CS,Thelmo W,Ahmed KS,Kumar A,Davidian M,Einhorn R,Adler J,McCarthy J

更新日期：1979-09-01 00:00:00

abstract：:Adhesive tape wound around the shaft of an upper GI endoscope serves as a simple method to dilate upper GI strictures under endoscopic control. This technique avoids the need for guidewires and fluoroscopy. ...

journal_title：Journal of clinical gastroenterology

authors： Lehman GA,O'Connor KW

更新日期：1985-06-01 00:00:00

abstract：:The role of the anorectal band in the genesis of hemorrhoids is studied. The anorectal band is a fibroepithelial tube which is a remnant of the anorectal sinus. Seventy-six hemorrhoid patients and 32 controls were studied. Rectal neck pressure recording was done for all subjects. Two biopsies were taken from the lower...

journal_title：Journal of clinical gastroenterology

authors： Shafik A

更新日期：1984-04-01 00:00:00

abstract：:Bacterial overgrowth is frequent in patients with Crohn's disease (CD) and can contribute to symptoms. Motility abnormalities can predispose to bacterial overgrowth. The hydrogen (H2) and methane (CH4) breath test is a sensitive and simple tool for the diagnosis of bacterial overgrowth and for the evaluation of orocec...

journal_title：Journal of clinical gastroenterology

authors： Castiglione F,Del Vecchio Blanco G,Rispo A,Petrelli G,Amalfi G,Cozzolino A,Cuccaro I,Mazzacca G

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Risk factors for osteoporotic fracture as well as inpatient utilization and mortality have not been thoroughly studied in patients with cirrhosis. We analyzed data from a national database to determine fracture risk in patients with cirrhosis, specific risk factors, and the effect of fractures on he...

journal_title：Journal of clinical gastroenterology

authors： Patel A,Silverman S,Baghdadi J,Shah O,Sundaram V

更新日期：2019-08-01 00:00:00

abstract：:In up to 10% to 20% of colonoscopies, complete intubation of the colon may be considerably difficult. A principal cause of difficulty is looping of the endoscope shaft in a floppy, often tortuous segment of the colon that typically happens in the sigmoid colon. Also, if looping is not recognized and the scope is advan...

journal_title：Journal of clinical gastroenterology

authors： Hawari R,Pasricha PJ

更新日期：2007-02-01 00:00:00

abstract：:One patient's story is recounted. Relatively asymptomatic for 20 years, the patient reflects on factors that contributed to his healing. Psychosocial and spiritual dimensions are described as well as biomedical aspects. The story concludes that dealing with Crohn's disease triggered a spiritual quest which in turn con...

journal_title：Journal of clinical gastroenterology

authors： Sheehan DR

更新日期：1998-06-01 00:00:00