Global aphasia as a predictor of mortality in the acute phase of a first stroke.

Abstract:

OBJECTIVE:To establish whether vascular aphasic syndromes can predict stroke outcomes. METHOD:Thirty-seven adults were evaluated for speech and language within 72 hours after a single first-ever ischemic brain lesion, in blind association to CT and/or MR. RESULTS:Speech or language disabilities were found in seven (87.5%) of the eight deceased patients and twenty-six (89.7%) of the twenty-nine survivors. Global aphasia was identified in eleven patients, all with left hemisphere lesions (nine mute; five deceased), consisting on a risk factor for death in the acute stroke phase (ρ=0.022). Age (z=1.65; ρ>0.09), thrombolysis (ρ=0.591), infarct size (ρ=0.076) and side (ρ=0.649) did not significantly influence survival. Absence of aphasia did not predict a better evolution, regardless of the affected hemisphere. Prevalence of cardiovascular risk factors was similar for all patient groups. CONCLUSION:Global aphasia in acute stroke can adversely affect prognosis, translated into impairment of dominant perisylvian vascular territories, with mutism as an important semiological element.

journal_name

Arq Neuropsiquiatr

authors

Oliveira FF,Damasceno BP

doi

10.1590/s0004-282x2011000300002

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

277-82

issue

2B

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2011000300002

journal_volume

69

pub_type

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