Treatment of irritable bowel syndrome in women.

Abstract:

:Irritable bowel syndrome (IBS) is a complex clinical process with multiple pathophysiologic mechanisms. There has recently been a shift in the treatment of patients with severe IBS symptoms to disease-modifying therapies as opposed to symptomatic treatment. Because pathophysiologic differences exist between men and women, so does the efficacy of treatment options. These differences could further explain gender-related differences in disease prevalence and treatment response. A brief discussion of the definition, epidemiology, and diagnostic criteria of IBS is followed by a comprehensive review of the current treatment choices and potential future therapeutic options of IBS in women.

authors

Tsynman DN,Thor S,Kroser JA

doi

10.1016/j.gtc.2011.03.012

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

265-90, vii

issue

2

eissn

0889-8553

issn

1558-1942

pii

S0889-8553(11)00030-6

journal_volume

40

pub_type

杂志文章,评审
  • Gastrointestinal manifestations of AIDS.

    abstract::As the AIDS epidemic continues to grow, it becomes increasingly important that physicians are aware of the gastrointestinal and abdominal diseases specific to this group of patients. Most AIDS patients exhibit gastrointestinal symptoms at some time during the course of their disease. Clinical AIDS is often determined ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Yee J,Wall SD

    更新日期:1995-06-01 00:00:00

  • Current Perspectives on Gastric Cancer.

    abstract::Gastric cancer (GC) is third leading cause of cancer-related death. Only 28.3% of new GC cases survive more than 5 years. Although incidence has declined in the United States, an increase is estimated for 2016. Risk factors include sex (risk is higher in men), Helicobacter pylori infection, heredity, and lifestyle. GC...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2016.04.002

    authors: Marqués-Lespier JM,González-Pons M,Cruz-Correa M

    更新日期:2016-09-01 00:00:00

  • The pharmacological therapy of non-variceal upper gastrointestinal bleeding.

    abstract::The modern management of patients with upper gastrointestinal bleeding includes, in selected patients, the performance of timely multimodal endoscopic hemostasis followed by profound acid suppression. This article discusses the available data on the use of antisecretory regimens in the management of patients with blee...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.08.002

    authors: Greenspoon J,Barkun A

    更新日期:2010-09-01 00:00:00

  • The role of cystic fibrosis gene mutations in determining susceptibility to chronic pancreatitis.

    abstract::This article reviews current concepts regarding the pathobiology of cystic fibrosis pancreatic disease. It summarizes recent studies on the relationship between CFTR mutations and pancreatitis, and it reviews several unresolved issues in the field. ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2004.07.008

    authors: Cohn JA,Mitchell RM,Jowell PS

    更新日期:2004-12-01 00:00:00

  • Morbid obesity: definitions, epidemiology, and methodological problems.

    abstract::This article defines obesity, ideal body weight, morbid obesity, and indexes of overweight, pointing out some of the difficulties in studies of the epidemiology of morbid obesity. ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章

    doi:

    authors: Kral JG,Heymsfield S

    更新日期:1987-06-01 00:00:00

  • Diet options of obesity: fad or famous?

    abstract::This article highlights the different dietary approaches that have evolved and become popular over the past few years. Whether these are fads or truly represent important changes in the way peo-ple eat and that ultimately will lead to a lower rate of obesity and improved health is impossible to know. ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2004.12.007

    authors: Balart LA

    更新日期:2005-03-01 00:00:00

  • Complementary and alternative medicine for the irritable bowel syndrome.

    abstract::Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder, characterized by chronic or recurrent abdominal pain and bloating. Complementary and alternative medicine (CAM) is a diverse group of medical treatments that are not commonly considered to be a part of conventional medicine yet frequently us...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.12.005

    authors: Magge S,Lembo A

    更新日期:2011-03-01 00:00:00

  • Inborn Errors of Metabolism and the Gastrointestinal Tract.

    abstract::Inborn errors of metabolism (IEMs) are usually recognized by characteristic neurologic and metabolic manifestations and sometimes by dysmorphism. However, IEMs can present with a wide variety of gastrointestinal manifestations, whether as the primary or a minor clinical symptom. Regardless, gastrointestinal and hepati...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2019.02.001

    authors: Guerrero RB,Kloke KM,Salazar D

    更新日期:2019-06-01 00:00:00

  • Morphology of Barrett's esophagus and Barrett's-associated dysplasia and adenocarcinoma.

    abstract::This article has reviewed the morphologic features of BE and its complications of dysplasia and adenocarcinoma in routinely processed endoscopic biopsy and resection specimens. In addition, the problems related to the diagnosis of dysplasia in tissue samples have been analyzed, and the role of esophageal brush cytolog...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70309-5

    authors: Antonioli DA,Wang HH

    更新日期:1997-09-01 00:00:00

  • Improving Care in Pediatric Inflammatory Bowel Disease.

    abstract::Pediatric patients with inflammatory bowel disease (IBD) stand to benefit from quality improvement (QI) due to the chronic nature of the disease, frequent interaction with the health care system, and exposure to high-risk treatments. The use of QI in health care has led to significant improvements in quality and relia...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2018.07.013

    authors: Egberg MD,Kappelman MD,Gulati AS

    更新日期:2018-12-01 00:00:00

  • Clinical presentation and pathophysiology of gastroparesis.

    abstract::Gastroparesis is a heterogeneous disorder defined by delay in gastric emptying. Symptoms of gastroparesis are nonspecific, including nausea, vomiting, early satiety, bloating, and/or abdominal pain. Normal gastric motor function and sensory function depend on a complex coordination between the enteric and central nerv...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2014.11.003

    authors: Nguyen LA,Snape WJ Jr

    更新日期:2015-03-01 00:00:00

  • The role of radiation therapy for colorectal cancer.

    abstract::Radiation therapy (RT) has been used to treat cancers for more than a century. Recent randomized trials have helped clarify the treatment recommendations in the use of RT for colorectal cancers. This article reviews these trials to illustrate key concepts, places these trials in perspective, and provides direction for...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2007.12.010

    authors: Robertson JM

    更新日期:2008-03-01 00:00:00

  • Biliary atresia.

    abstract::BA is a rare disease of unclear etiology; nevertheless, its impact in the field of pediatric hepatology is significant. It is the most common surgically correctable cause of neonatal cholestasis and is the most common pediatric disease referred for liver transplantation. Little progress has been made with regard to im...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(03)00049-9

    authors: Haber BA,Russo P

    更新日期:2003-09-01 00:00:00

  • Management of gastrointestinal bleeding induced by gastrointestinal endoscopy.

    abstract::Therapeutic gastrointestinal endoscopy has a much greater risk of inducing gastrointestinal hemorrhage than diagnostic endoscopy. For example, colonoscopic polypectomy has a risk of approximately 1.6% of inducing bleeding, compared with a risk of approximately 0.02% for diagnostic colonoscopy. Higher-risk procedures i...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70110-2

    authors: Cappell MS,Abdullah M

    更新日期:2000-03-01 00:00:00

  • Microbiology of Helicobacter pylori.

    abstract::The new genus name Helicobacter was first published in October 1989. H. pylori is a unipolar, multiflagellate, gently spiral organism found on the human gastric mucosa, but in culture and under unfavorable conditions, coccoidal forms emerge, which may be indicative of a dormant state. The biology and metabolism of H. ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Goodwin CS,Worsley BW

    更新日期:1993-03-01 00:00:00

  • Diagnosis of irritable bowel syndrome.

    abstract::Because there are no reliable biological or laboratory markers associated with the condition, the diagnosis of irritable bowel syndrome(IBS) is based on patient descriptions of common symptoms such as abdominal pain accompanied by changes in stool form or frequency and associated symptoms such as bloating and distensi...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2005.03.001

    authors: Cash BD,Chey WD

    更新日期:2005-06-01 00:00:00

  • Imaging in Autoimmune Pancreatitis and Immunoglobulin G4-Related Disease of the Abdomen.

    abstract::Autoimmune pancreatitis (AIP) is steroid-responsive fibroinflammatory disorder of the pancreas. There are 2 distinct subtypes of AIP, types 1 and 2. Type 1 is associated with systemic immunoglobulin (Ig)G4 disease and may affect multiple organs in the body. Type 2 is confined to the pancreas and shows an association w...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2018.04.007

    authors: Sandrasegaran K,Menias CO

    更新日期:2018-09-01 00:00:00

  • Bleeding peptic ulcer: pathogenesis and endoscopic therapy.

    abstract::The presence of stigmata of hemorrhage in a peptic ulcer indicate an increased risk of rebleeding and the need for endoscopic intervention. Clinical trials indicate that laser photocoagulation, multipolar and heater probe coagulation, and injection therapy are all effective in decreasing bleeding from peptic ulcer dis...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Zuccaro G Jr

    更新日期:1993-12-01 00:00:00

  • Epidemiology of cholera in the Americas.

    abstract::A persisting reservoir of the Gulf Coast strain of toxigenic V. cholerae O1 in Louisiana and Texas marshes and the shipment of seafood from these areas throughout the United States means that sporadic cases and outbreaks of cholera may occur anywhere in the country for the foreseeable future. Such cases are most likel...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Blake PA

    更新日期:1993-09-01 00:00:00

  • Relationship of hormones and growth factors to colon cancer.

    abstract::The role of hormones and growth factors in the pathogenesis and therapy of colon cancer is biologically intricate and medically important. The effects of the previously described hormones and growth factors on normal and neoplastic colonic growth and development suggest the mechanisms by which hormonal alteration migh...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Conteas CN,Desai TK,Arlow FA

    更新日期:1988-12-01 00:00:00

  • Biopsy Diagnosis of Celiac Disease: The Pathologist's Perspective in Light of Recent Advances.

    abstract::Celiac disease is a common immune-mediated disorder that occurs in individuals with permissive genetics (HLA-DQ2/DQ8 genotype) following exposure to certain wheat proteins. The histopathologic manifestations of small intestinal mucosal injury (villus atrophy, crypt hyperplasia, and intraepithelial lymphocytosis) are w...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2018.09.003

    authors: Lagana SM,Bhagat G

    更新日期:2019-03-01 00:00:00

  • Assessment of quality of life outcomes in the treatment of advanced colorectal malignancies.

    abstract::QOL assessment in oncology has made great strides in recent years. There was a difficult time initially, during which QOL tools were "thrown in" to many clinical trials as an afterthought, without a pre-specified scientific question. As expected from such a scattershot approach, the results were underwhelming and disa...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2005.12.010

    authors: Hassan I,Cima RC,Sloan JA

    更新日期:2006-03-01 00:00:00

  • Acute acalculous cholecystitis.

    abstract::Acute acalculous cholecystitis (ACC) can develop with or without gallstones after surgery and in critically ill or injured patients. Diabetes mellitus, malignant disease, abdominal vasculitis, congestive heart failure, cholesterol embolization, shock, and cardiac arrest also have been associated with AAC. The pathogen...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.02.012

    authors: Barie PS,Eachempati SR

    更新日期:2010-06-01 00:00:00

  • New observations on the gastroesophageal antireflux barrier.

    abstract::The use of high-frequency ultrasound transducers combined with manometry in the gastrointestinal (GI) tract has yielded important findings concerning the anatomy, physiology, and pathophysiology of the high-pressure zone of the gastroesophageal junction and the sphincteric muscles within. These transducers have made p...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2007.07.008

    authors: Miller L,Vegesna A,Kalra A,Besetty R,Dai Q,Korimilli A,Brasseur JG

    更新日期:2007-09-01 00:00:00

  • The role of FDG-PET and staging laparoscopy in the management of patients with cancer of the esophagus or gastroesophageal junction.

    abstract::The effort to improve outcomes in esophageal cancer has included attempts at improving staging and patient selection. 2-Deoxy-2-[(18)F]fluoro-Dglucose positron emission tomography (FDG-PET) has been extensively studied in this context and has been widely accepted as a staging tool. Its role in restaging or assessing t...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2009.01.007

    authors: Yoon HH,Lowe VJ,Cassivi SD,Romero Y

    更新日期:2009-03-01 00:00:00

  • Diarrhea in chronic inflammatory bowel diseases.

    abstract::Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence. The pathophysiology of diarrhea in these diseases is complex, but defective absorption of salt and water by the inflamed bowel is the most important mechanism involved. In add...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2012.06.006

    authors: Wenzl HH

    更新日期:2012-09-01 00:00:00

  • Ischemic bowel disease in the elderly.

    abstract::The ischemic bowel diseases are a heterogeneous group of disorders usually seen in elderly individuals. They represent ischemic damage to different portions [figure: see text] of the bowel and produce a variety of clinical syndromes and outcomes. Colonic ischemia is the commonest of these disorders and has a favorable...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70190-4

    authors: Greenwald DA,Brandt LJ,Reinus JF

    更新日期:2001-06-01 00:00:00

  • Balancing risks and benefits of cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs.

    abstract::Choosing NSAID therapy remains confusing and controversial-the challenge for the clinician is to sum all the risks as well as analgesic and anti-inflammatory efficacy. COX-2 inhibitors are an important scientific advance in pain therapy, and using them in a safe and cost-effective manner is possible when all the compe...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2009.03.006

    authors: Scheiman JM

    更新日期:2009-06-01 00:00:00

  • Constipation and diarrhea in pregnancy.

    abstract::Constipation and diarrhea are common during pregnancy, occurring in up to one-third of women. Constipation is often the result of physiologic changes that occur during pregnancy, usually from hormonal effects on gastrointestinal motility. Diarrhea, on the other hand, is often caused by the same disorders responsible f...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70353-8

    authors: Bonapace ES Jr,Fisher RS

    更新日期:1998-03-01 00:00:00

  • Update on Therapeutic Drug Monitoring in Crohn's Disease.

    abstract::In patients with Crohn's disease on biologic medications, the use of therapeutic drug monitoring leads to a personalized approach to optimize treatment. Using an algorithmic approach, measurement of drug concentrations and anti-drug antibodies can be used to improve treatment outcomes. Therapeutic drug concentrations ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2017.05.014

    authors: Heron V,Afif W

    更新日期:2017-09-01 00:00:00