The pharmacological therapy of non-variceal upper gastrointestinal bleeding.

abstract：:Diverticulitis represents a spectrum of clinical entities ranging from minimal pericolitis in the adjacent mesentery to uncontrolled intra-abdominal sepsis and septic shock. The presentation most often described is left lower quadrant abdominal pain, fever, chills, and left lower quadrant tenderness associated with a ...

journal_title：Gastroenterology clinics of North America

authors： Pohlman T

更新日期：1988-06-01 00:00:00

abstract：:Autoimmune pancreatitis (AIP) is steroid-responsive fibroinflammatory disorder of the pancreas. There are 2 distinct subtypes of AIP, types 1 and 2. Type 1 is associated with systemic immunoglobulin (Ig)G4 disease and may affect multiple organs in the body. Type 2 is confined to the pancreas and shows an association w...

journal_title：Gastroenterology clinics of North America

authors： Sandrasegaran K,Menias CO

更新日期：2018-09-01 00:00:00

abstract：:Precursor lesions in the GIT include flat dysplasias, adenomas, dysplasia superimposed on nonneoplastic polyps, endocrine cell dysplasia, ACF, and condyloma accuminatum. Interobserver variability can be a problem in reporting dysplasia, and ancillary techniques including flow cytometry, image analysis, proliferation m...

journal_title：Gastroenterology clinics of North America

authors： Haber MM

更新日期：2002-06-01 00:00:00

abstract：:Arguments proposed in this article may explain why a subgroup of patients, having so-called "functional heartburn," does not respond to acid inhibition therapy [19,20]. It is highly likely that acid is not the cause of heartburn in this group of subjects. These conclusions are supported further by observations of Wien...

journal_title：Gastroenterology clinics of North America

authors： Steinbach J,Fass R,Mittal RK

更新日期：2002-12-01 00:00:00

abstract：:This article has reviewed the morphologic features of BE and its complications of dysplasia and adenocarcinoma in routinely processed endoscopic biopsy and resection specimens. In addition, the problems related to the diagnosis of dysplasia in tissue samples have been analyzed, and the role of esophageal brush cytolog...

journal_title：Gastroenterology clinics of North America

authors： Antonioli DA,Wang HH

更新日期：1997-09-01 00:00:00

abstract：:Managed care organizations and their products will continue to change in response to consumer demands, competitive pressures, and regulatory requirements. Providers who gain an understanding of the world managed care organizations live in can also expect to influence these organizations for mutual benefit. Just as man...

journal_title：Gastroenterology clinics of North America

authors： Behnke LM

更新日期：1997-12-01 00:00:00

abstract：:Numerous extraintestinal diseases have been associated with IBD. The role of the gastrointestinal tract in host response to the foreign antigens present in the gut makes the enteric immune system highly susceptible to any external perturbation to the system. Dysregulation of the enteric immune response results in path...

journal_title：Gastroenterology clinics of North America

authors： Su CG,Judge TA,Lichtenstein GR

更新日期：2002-03-01 00:00:00

abstract：:The use of high-frequency ultrasound transducers combined with manometry in the gastrointestinal (GI) tract has yielded important findings concerning the anatomy, physiology, and pathophysiology of the high-pressure zone of the gastroesophageal junction and the sphincteric muscles within. These transducers have made p...

journal_title：Gastroenterology clinics of North America

authors： Miller L,Vegesna A,Kalra A,Besetty R,Dai Q,Korimilli A,Brasseur JG

更新日期：2007-09-01 00:00:00

abstract：:Current practice guidelines recommend annual fecal occult blood test screening for colorectal cancer in the average-risk population over the age of 50. Efficacy of fecal occult blood test screening is supported by several controlled prospective trials and case-control studies. Implementation of this recommendation, in...

journal_title：Gastroenterology clinics of North America

authors： Bond JH

更新日期：1997-03-01 00:00:00

abstract：:This article defines obesity, ideal body weight, morbid obesity, and indexes of overweight, pointing out some of the difficulties in studies of the epidemiology of morbid obesity. ...

journal_title：Gastroenterology clinics of North America

authors： Kral JG,Heymsfield S

更新日期：1987-06-01 00:00:00

abstract：:The management of recurrent, symptomatic malignant ascites can be problematic for physicians and patients. The most common, low-risk method is large-volume paracentesis. Patient disease progression often leads to rapid reaccumulation of ascites, which requires frequent return visits to the hospital for symptom managem...

journal_title：Gastroenterology clinics of North America

authors： Rosenberg SM

更新日期：2006-03-01 00:00:00

abstract：:A wide spectrum of gastrointestinal illnesses impairs bone health and can result in bone pain, demineralization, and fracture. This article summarizes current knowledge of the skeletal pathology exhibited in patients with diseases of the liver, biliary tree, pancreas, and bowel. Mechanisms responsible for these syndro...

journal_title：Gastroenterology clinics of North America

authors： Lipkin EW

更新日期：1998-06-01 00:00:00

abstract：:Crohn's disease is not medically (and is rarely surgically) curable. Patients do, however, live a normal life span. The goal of therapy is to optimize the quality of life, minimize disease activity and disease-related complications, and avoid therapeutic toxicity. ...

journal_title：Gastroenterology clinics of North America

authors： Harrison J,Hanauer SB

更新日期：2002-03-01 00:00:00

abstract：:Celiac disease is a common immune-mediated disorder that occurs in individuals with permissive genetics (HLA-DQ2/DQ8 genotype) following exposure to certain wheat proteins. The histopathologic manifestations of small intestinal mucosal injury (villus atrophy, crypt hyperplasia, and intraepithelial lymphocytosis) are w...

journal_title：Gastroenterology clinics of North America

authors： Lagana SM,Bhagat G

更新日期：2019-03-01 00:00:00

abstract：:The success of gastric bypass probably depends on factors other than merely the restrictive size of the gastric pouch and outlet. Postoperative dumping and a mild degree of malabsorption derived from the redirection of intestinal contents contribute to long-term success. Thus, gastric bypass combines some elements of ...

journal_title：Gastroenterology clinics of North America

authors： Flickinger EG,Sinar DR,Swanson M

更新日期：1987-06-01 00:00:00

abstract：:CD and UC represent a spectrum of chronic IBD that present in protean ways and are accompanied by a variety of systemic sequelae. Sulfasalazine and the newer 5-aminosalicylates are important in the management of mild-to-moderate disease, whereas corticosteroids remain the primary therapy for most patients with moderat...

journal_title：Gastroenterology clinics of North America

authors： Stein RB,Hanauer SB

更新日期：1999-06-01 00:00:00

abstract：:Tobacco and alcohol use are strong risk factors for cancer of the upper gastrointestinal tract. Saturated fat and red meat intake also appear to increase the risk of colorectal cancer. The strongest and most consistent dietary protective factors for gastrointestinal cancer are vegetables and fruits. Some micronutrient...

journal_title：Gastroenterology clinics of North America

authors： Hensrud DD,Heimburger DC

更新日期：1998-06-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is defined by either subjective complaints indicative of problematic gastroesophageal reflux or objective complications directly attributable to reflux. Studies focused on GERD-related symptoms suggest a worldwide increase in prevalence of approximately 4% per year. Epidemiologic...

journal_title：Gastroenterology clinics of North America

authors： Pandolfino JE,Kwiatek MA,Kahrilas PJ

更新日期：2008-12-01 00:00:00

abstract：:High-resolution manometry (HRM) allows nuanced evaluation of esophageal motor function, and more accurate evaluation of lower esophageal sphincter (LES) function, in comparison with conventional manometry. Pathophysiologic correlates of gastroesophageal reflux disease (GERD) and esophageal peristaltic performance are ...

journal_title：Gastroenterology clinics of North America

authors： Mello M,Gyawali CP

更新日期：2014-03-01 00:00:00

abstract：:Cholesterol gallstone disease is reversible and can be treated medically with either CDCA or UDCA. Both bile acids correct the hepatic metabolic defect that is responsible for hypersecretion of cholesterol into the bile, and both desaturate the bile. UDCA is preferred because it is more effective, desaturate the bile ...

journal_title：Gastroenterology clinics of North America

authors： Salen G,Tint GS,Shefer S

更新日期：1991-03-01 00:00:00

abstract：:Preeclampsia has traditionally been viewed as one of several forms of hypertension complicating pregnancy. More recently, the multisystem nature of this unique gestational disorder has been emphasized. Pathophysiologic events, including abnormal placentation and heightened vascular reactivity, may occur weeks or month...

journal_title：Gastroenterology clinics of North America

authors： Barron WM

更新日期：1992-12-01 00:00:00

abstract：:Constipation, diarrhea, and symptomatic hemorrhoids are disorders common in the general population, particularly in women. These conditions, if mild, often are self-treated with various home remedies or nonprescription preparations. Few of these patients, moreover, are referred to gastroenterologists, as primary care ...

journal_title：Gastroenterology clinics of North America

authors： Wald A

更新日期：2003-03-01 00:00:00

abstract：:Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence. The pathophysiology of diarrhea in these diseases is complex, but defective absorption of salt and water by the inflamed bowel is the most important mechanism involved. In add...

journal_title：Gastroenterology clinics of North America

authors： Wenzl HH

更新日期：2012-09-01 00:00:00

abstract：:In the treatment of arthritis, NSAIDs are some of the most commonly used drugs, although the prescription of such drugs has been questioned due to their inherent risks for gastrointestinal compromise, platelet effects, and the potential for renal toxicity with long-term use. With the availability of celecoxib and rofe...

journal_title：Gastroenterology clinics of North America

authors： Simon LS

更新日期：2001-12-01 00:00:00

abstract：:The evaluation and treatment of patients after operations on the foregut is a challenge for physicians and surgeons. The early postoperative period is an especially important interval because the very survival of the patient as well as the success of the surgical intervention depends on the correct interpretation of t...

journal_title：Gastroenterology clinics of North America

authors： Donahue PE

更新日期：1994-06-01 00:00:00

abstract：:Three (author's standard) or five biopsy specimens (two antral, two corpus, one incisura) as suggested by the Sydney system (original and revised version) [figure: see text] correctly separate infected mucosa from uninfected mucosa. No combination identified correctly the presence of intestinal metaplasia to be consid...

journal_title：Gastroenterology clinics of North America

authors： el-Zimaity HM

更新日期：2000-12-01 00:00:00

abstract：:This brief review summarizes the physiology and pharmacology of eicosanoids and describes how they have been tested for possible application in liver disease and transplantation. The objective is to trace the stepwise application from the laboratory to the bedside. Although many questions remain to be answered, the ob...

journal_title：Gastroenterology clinics of North America

authors： Ruwart MJ,Henley KS

更新日期：1996-06-01 00:00:00

abstract：:The presence of stigmata of hemorrhage in a peptic ulcer indicate an increased risk of rebleeding and the need for endoscopic intervention. Clinical trials indicate that laser photocoagulation, multipolar and heater probe coagulation, and injection therapy are all effective in decreasing bleeding from peptic ulcer dis...

journal_title：Gastroenterology clinics of North America

authors： Zuccaro G Jr

更新日期：1993-12-01 00:00:00

abstract：:As the AIDS epidemic continues to grow, it becomes increasingly important that physicians are aware of the gastrointestinal and abdominal diseases specific to this group of patients. Most AIDS patients exhibit gastrointestinal symptoms at some time during the course of their disease. Clinical AIDS is often determined ...

journal_title：Gastroenterology clinics of North America

authors： Yee J,Wall SD

更新日期：1995-06-01 00:00:00

abstract：:Pediatric patients with inflammatory bowel disease (IBD) stand to benefit from quality improvement (QI) due to the chronic nature of the disease, frequent interaction with the health care system, and exposure to high-risk treatments. The use of QI in health care has led to significant improvements in quality and relia...

journal_title：Gastroenterology clinics of North America

authors： Egberg MD,Kappelman MD,Gulati AS

更新日期：2018-12-01 00:00:00