Renal function in rats with angiotensin II-salt-induced hypertension: effect of thromboxane synthesis inhibition and receptor blockade.

abstract：OBJECTIVE:The objective of the study was to investigate interarm differences of blood pressure (BP) and its determinants, and to clarify whether both arms are equally good in assessing BP and target organ damage in the general population. METHODS:We studied a representative sample of Finnish adult population with 484 ...

journal_title：Journal of hypertension

authors： Johansson JK,Puukka PJ,Jula AM

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:The thiazide-sensitive Na-Cl cotransporter (TSC) is involved in the fine regulation of sodium excretion by the kidney, and an increase in its activity causes salt-sensitive hypertension and hypercalciuria. METHODS:To explore the possibility that activating mutations in the TSC gene may be involved in the pa...

journal_title：Journal of hypertension

authors： Keszei AP,Tislér A,Backx PH,Andrulis IL,Bull SB,Logan AG

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVES:Urotensin II is the most potent vasoconstrictor known. Its role in hypertension has not been investigated. Here, we studied the plasma levels in hypertensive and normotensive human subjects. DESIGN:A cross-sectional case-control study. SETTING:Hypertension clinic and research clinic of a university teachin...

journal_title：Journal of hypertension

authors： Cheung BM,Leung R,Man YB,Wong LY

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:The effects of aspirin in subjects without cardiovascular disease are controversial. In the intensively treated patients of the Hypertension Optimal Treatment (HOT) Study, randomization to low-dose aspirin (75 mg daily) versus placebo significantly reduced cardiovascular events (-15%) and myocardial infarcti...

journal_title：Journal of hypertension

authors： Zanchetti A,Hansson L,Dahlöf B,Julius S,Ménard J,Warnold I,Wedel H,HOT Study Group.

更新日期：2002-11-01 00:00:00

abstract：:Diabetic nephropathy has developed into a worldwide epidemic and is responsible for the majority of end-stage renal disease in most countries. Antihypertensive treatment slows the progression of the disease. In addition, blockade of the renin-angiotensin system reduces the degree of albuminuria and angiotensin II rece...

journal_title：Journal of hypertension

authors： Haller H,Viberti GC,Mimran A,Remuzzi G,Rabelink AJ,Ritz E,Rump LC,Ruilope LM,Katayama S,Ito S,Izzo JL Jr,Januszewicz A

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Secondary prevention of stroke with antihypertensive drugs is now standard practice, but it is unclear how soon after a cerebrovascular event antihypertensive therapy should be initiated or re-started. Due to impaired cerebral autoregulation, changes in systemic blood pressure may be reflected in cerebral pe...

journal_title：Journal of hypertension

authors： Nazir FS,Overell JR,Bolster A,Hilditch TE,Reid JL,Lees KR

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Sleep-disordered breathing, predominantly obstructive sleep apnea (OSA), is highly prevalent in patients with hypertension. OSA may underlie the progression to resistant hypertension, partly due to increased activation of the sympathetic nervous system. This analysis of patients with and without OSA evaluate...

journal_title：Journal of hypertension

authors： Linz D,Mancia G,Mahfoud F,Narkiewicz K,Ruilope L,Schlaich M,Kindermann I,Schmieder RE,Ewen S,Williams B,Böhm M,Global SYMPLICITY Registry Investigators.

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Hypertension is a complex trait with an ill-defined genetic predisposition, in which adrenergic mechanisms seem to be involved even at the early stages. Chromogranin A is a pro-hormone stored and released with catecholamines by exocytosis; its fragment catestatin, formed in vivo, inhibits further catecholami...

journal_title：Journal of hypertension

authors： O'Connor DT,Kailasam MT,Kennedy BP,Ziegler MG,Yanaihara N,Parmer RJ

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence and associated risks of white-coat hypertension (WCH) are still a matter of debate. We aimed to assess differences in prevalence and associated conditions of WCH defined on the basis of the normality of all daytime, night-time, and 24-h blood pressure (BP), only daytime, or only 24-h B...

journal_title：Journal of hypertension

authors： de la Sierra A,Vinyoles E,Banegas JR,Segura J,Gorostidi M,de la Cruz JJ,Ruilope LM

更新日期：2017-12-01 00:00:00

abstract：:: High blood pressure (BP) is a highly prevalent modifiable cause of cardiovascular disease, stroke, and death. Accurate BP measurement is critical, given that a 5-mmHg measurement error may lead to incorrect hypertension status classification in 84 million individuals worldwide. This position statement summarizes pro...

journal_title：Journal of hypertension

authors： Padwal R,Campbell NRC,Schutte AE,Olsen MH,Delles C,Etyang A,Cruickshank JK,Stergiou G,Rakotz MK,Wozniak G,Jaffe MG,Benjamin I,Parati G,Sharman JE

更新日期：2019-09-01 00:00:00

abstract：:This paper describes the kinetics of the Na(+)-K+ pump and the Na(+)-K(+)-Cl- cotransport in sodium-loaded erythrocytes and of the Na(+)-K(+)-Cl- cotransport in erythrocyte inside-out vesicles (IOV) from Milan hypertensive (MHS) and normotensive (MNS) rats in order to evaluate the possible role of intracellular factor...

journal_title：Journal of hypertension

authors： Ferrari P,Torielli L,Cirillo M,Salardi S,Bianchi G

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:To describe several emerging concepts regarding the biosynthesis, metabolism and biological roles of adenosine and to illustrate the possible significance of these ideas to vascular biology by proposing a hypothesis pertaining to the role of erythrocyte-derived adenosine deaminase in vaso-occlusive diseases a...

journal_title：Journal of hypertension

authors： Jackson EK,Koehler M,Mi Z,Dubey RK,Tofovic SP,Carcillo JA,Jones GS

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:Nailfold capillary density was measured at rest and after 4 min circulatory arrest in order to investigate the relationship between sodium-sensitive hypertension and microvessel density. DESIGN:Seventeen sodium-sensitive and 28 sodium-resistant young borderline hypertensive males and 10 normotensive controls...

journal_title：Journal of hypertension

authors： Draaijer P,de Leeuw PW,van Hooff JP,Leunissen KM

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the role of transforming growth factor (TGF)-beta1 in the development of diabetes-associated mesenteric vascular hypertrophy and in the antitrophic effect of angiotensin converting enzyme inhibitors. DESIGN AND METHODS:Streptozotocin-induced diabetic and control Spragu...

journal_title：Journal of hypertension

authors： Rumble JR,Gilbert RE,Cox A,Wu L,Cooper ME

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:Ethnic minority populations (EMPs) are disproportionally affected by hypertension-mediated complications compared with European host populations (EHPs), which might be due to disparities in hypertension awareness, treatment and control. We conducted a systematic review and meta-analysis to compare awareness, ...

journal_title：Journal of hypertension

authors： van der Linden EL,Couwenhoven BN,Beune EJAJ,Daams JG,van den Born BH,Agyemang C

更新日期：2021-02-01 00:00:00

abstract：:The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 confirms ischemic heart disease and stroke as the leading cause of death and that hypertension is the main associated risk factor worldwide. How best to respond to the rising prevalence of hypertension in resource-deprived settings is a topic of ongo...

journal_title：Journal of hypertension

authors： Modesti PA,Agostoni P,Agyemang C,Basu S,Benetos A,Cappuccio FP,Ceriello A,Del Prato S,Kalyesubula R,O'Brien E,Kilama MO,Perlini S,Picano E,Reboldi G,Remuzzi G,Stuckler D,Twagirumukiza M,Van Bortel LM,Watfa G,Zhao D

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To determine the relationship between arterial function (stiffness and wave reflection) and glomerular hemodynamics. METHODS:In 49 healthy normotensive individuals, glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured by urinary clearances of 99mTC-DTPA and 131I-hippuran, res...

journal_title：Journal of hypertension

authors： Fesler P,du Cailar G,Ribstein J,Mimran A

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:The use of thiazide diuretics in the treatment of hypertension is widely considered as a first-line treatment, given the efficacy and low cost of this class of drugs. This indication is not unanimous, because thiazides can cause metabolic alterations, and other side effects that reduce compliance and persist...

journal_title：Journal of hypertension

authors： Trimarco V,de Simone G,Izzo R,De Luca N,Giudice R,Marino M,Damiano S,Rozza F,Trimarco B,Di Renzo G

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:The objective of the present studies is to investigate if the enhanced expression of Gs alpha protein and their mRNA observed in various models of hypertensive rats is due to the expressed hypertrophy or hypertension. METHODS:Hypertension, in Sprague-Dawley rats was induced by the oral administration of the ...

journal_title：Journal of hypertension

authors： Di Fusco F,Anand-Srivastava MB

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVES:Current evidence demonstrates that both genetic and environmental factors influence blood pressure. The sympathetic nervous system is a key player in blood pressure control and functional genetic variants of the beta-2 adrenergic receptor (B2AR) have been identified and implicated in the pathogenesis of hype...

journal_title：Journal of hypertension

authors： Binder A,Garcia E,Wallace C,Gbenga K,Ben-Shlomo Y,Yarnell J,Brown P,Caulfield M,Skrabal F,Kotanko P,Munroe P

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:To determine whether blood pressure levels in adult life are related to the mother's fetal growth and size at birth. DESIGN:A follow-up study of men and women whose mothers' or fathers' size at birth was recorded in Preston, Lancashire, UK. SUBJECTS:Two hundred and twenty-eight men and women born in Preston...

journal_title：Journal of hypertension

authors： Barker DJ,Shiell AW,Barker ME,Law CM

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:Hypertensive rats are more sensitive to the pressor effects of acute ouabain than normotensive rats. We analyzed the effect of chronic ouabain (approximately 8.0 microg/day, 5 weeks) treatment on the blood pressure of spontaneously hypertensive rats (SHRs) and Wistar-Kyoto rats and the contribution of vascula...

journal_title：Journal of hypertension

authors： Xavier FE,Davel AP,Fukuda LE,Rossoni LV

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVE:In essential hypertension, the mechanical properties of the radial artery have been shown to be largely unaltered, whereas more controversial and less reliable data have been obtained for the common carotid artery. We therefore examined the distensibility/pressure relationships of the predominantly elastic co...

journal_title：Journal of hypertension

authors： Stella ML,Mircoli L,Mangoni AA,Giannattasio C,Ferrari AU,Mancia G

更新日期：1997-12-01 00:00:00

abstract：:: The hypertension paradigm has contributed to a dramatic reduction in CVD mortality. This has been achieved by applying average results of population studies to identify a target population and design a common intervention to achieve a BP goal. Progressive lowering of the BP threshold has expanded the fraction of per...

journal_title：Journal of hypertension

authors： Alderman MH,Blumenfeld JD

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:Increased wall-to-lumen ratio of small arteries is a predictor of adverse cardiovascular prognosis. We aimed to analyze retinal arteriolar structure in never-treated patients with essential hypertension and to test whether elevated blood pressure is associated with an increased wall-to-lumen ratio of retinal ...

journal_title：Journal of hypertension

authors： Ritt M,Harazny JM,Ott C,Schlaich MP,Schneider MP,Michelson G,Schmieder RE

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To compare the elastic properties of the ascending aorta and ventricular-arterial coupling (VAC) in women with a previous pregnancy complicated by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome, women who experienced preeclampsia, and healthy controls. METHODS:Women with a history of p...

journal_title：Journal of hypertension

authors： Sciatti E,Orabona R,Prefumo F,Vizzardi E,Bonadei I,Valcamonico A,Metra M,Frusca T

更新日期：2019-02-01 00:00:00

abstract：:Although the blood vessels are exposed to high pressures in hypertension, the main complications of hypertension (stroke and myocardial infarction) are paradoxically thrombotic rather than haemorrhagic. In keeping with Virchow's triad, patients with hypertension do demonstrate abnormalities of vessel wall (endothelial...

journal_title：Journal of hypertension

authors： Lip GY,Li-Saw-Hee FL

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To study 24-h ambulatory blood pressure (BP) and development of hypertension over four decades in women with childhood urinary tract infection (UTI) associated with renal damage. METHODS:A population-based group of 111 women was followed from their first UTI in childhood. The cohort was investigated at a med...

journal_title：Journal of hypertension

authors： Gebäck C,Hansson S,Himmelmann A,Sandberg T,Sixt R,Jodal U

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:Aortic (central) blood pressure (BP) differs from brachial BP and may be a superior predictor of cardiovascular events. However, its measurement is currently restricted to research settings, owing to a moderate level of operator dependency. We tested a new noninvasive device in a large UK cohort. The device ...

journal_title：Journal of hypertension

authors： Park CM,Korolkova O,Davies JE,Parker KH,Siggers JH,March K,Tillin T,Chaturvedi N,Hughes AD

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Although an exaggerated systolic blood pressure (SBP) response to exercise is a predictor of future hypertension and cardiovascular mortality, the underlying mechanisms are not fully understood. We tested the hypothesis that an exaggerated SBP response is associated with carotid atherosclerosis in a cross-sec...

journal_title：Journal of hypertension

authors： Jae SY,Fernhall B,Heffernan KS,Kang M,Lee MK,Choi YH,Hong KP,Ahn ES,Park WH

更新日期：2006-05-01 00:00:00