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Synthesis of rare sugars with L-fuculose-1-phosphate aldolase (FucA) from Thermus thermophilus HB8.

Abstract：

:We report herein a one-pot four-enzyme approach for the synthesis of the rare sugars d-psicose, d-sorbose, l-tagatose, and l-fructose with aldolase FucA from a thermophilic source (Thermus thermophilus HB8). Importantly, the cheap starting material DL-GP (DL-glycerol 3-phosphate), was used to significantly reduce the synthetic cost.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Li Z,Cai L,Qi Q,Styslinger TJ,Zhao G,Wang PG

doi

10.1016/j.bmcl.2011.03.072

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

5084-7

issue

17

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(11)00391-X

journal_volume

21

pub_type

杂志文章

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