A systems biology approach to the evolution of plant-virus interactions.

Abstract:

:Omic approaches to the analysis of plant-virus interactions are becoming increasingly popular. These types of data, in combination with models of interaction networks, will aid in revealing not only host components that are important for the virus life cycle, but also general patterns about the way in which different viruses manipulate host regulation of gene expression for their own benefit and possible mechanisms by which viruses evade host defenses. Here, we review studies identifying host genes regulated by viruses and discuss how these genes integrate in host regulatory and interaction networks, with a particular focus on the physical properties of these networks.

journal_name

Curr Opin Plant Biol

authors

Elena SF,Carrera J,Rodrigo G

doi

10.1016/j.pbi.2011.03.013

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

372-7

issue

4

eissn

1369-5266

issn

1879-0356

pii

S1369-5266(11)00025-2

journal_volume

14

pub_type

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