Novel biological insights revealed from cell type-specific expression profiling.

Abstract:

:Transcriptional regulation plays a major role in defining cell identity. Analysis of cell type-resolution expression profiling datasets is moving beyond cataloging gene expression patterns to reveal novel biological insights. Recently developed expression maps of the shoot apical meristem and gametophytes can be used as tools to help define novel cell types and pathways. Already these maps have revealed cell type-specific epigenetic regulatory mechanisms that play important roles in development. Further examples are provided that demonstrate how cell type-specific expression profiling can also be used to uncover genes and pathways in development and response to stress that would be nearly impossible to identify using traditional genetics.

journal_name

Curr Opin Plant Biol

authors

Taylor-Teeples M,Ron M,Brady SM

doi

10.1016/j.pbi.2011.05.007

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

601-7

issue

5

eissn

1369-5266

issn

1879-0356

pii

S1369-5266(11)00085-9

journal_volume

14

pub_type

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