Conversion from sirolimus to everolimus in kidney transplant recipients receiving a calcineurin-free regimen.

abstract：BACKGROUND:It is unclear whether sirolimus, a newer immunosuppressive agent, widely used in renal transplantation, affects male sex hormone levels or sexual function. METHODS:Sex hormone profiles in male renal transplant recipients were obtained and compared between a sirolimus-treated group and a group not on sirolim...

journal_title：Clinical transplantation

authors： Lee S,Coco M,Greenstein SM,Schechner RS,Tellis VA,Glicklich DG

更新日期：2005-04-01 00:00:00

abstract：:This paper describes 108 consecutively treated patients receiving 109 cadaveric (CD) and living donor (LD) renal allografts using a protocol of quadruple sequential immunosuppression with a rabbit anti-human thymocyte IgG (Thymoglobuline), azathioprine, tapering corticosteroids, and delayed introduction of cyclosporin...

journal_title：Clinical transplantation

authors： Guttmann RD,Flemming C

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Numerous studies of steroid withdrawal have been carried out in kidney and liver transplant recipients, but only a few in pancreas transplant recipients. Yet, pancreas transplant recipients could have significant long-term benefits from steroid withdrawal. METHODS:We performed a retrospective analysis to de...

journal_title：Clinical transplantation

authors： Humar A,Parr E,Drangstveit MB,Kandaswamy R,Gruessner AC,Sutherland DE

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). In fact, death from cardiovascular disease is the number one cause of graft loss in kidney transplant (KTx) patients. Compared to patients on dialysis, CKD patients with KTx have increased qu...

journal_title：Clinical transplantation

authors： Tooley JE,Bohl DD,Kulkarni S,Rodriguez-Davalos MI,Mangi A,Mulligan DC,Yoo PS

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:Urinary tract infections (UTIs) account for significant morbidity after kidney transplantation (KT). Screening for asymptomatic bacteruria (AB) has proven to be beneficial in certain population including pregnant women; however, it is not well-studied in KT population. We reviewed the incidence, clinical feat...

journal_title：Clinical transplantation

authors： Goh YSB,Deng Z,Cheong PSC,Raman L,Goh THA,Vathsala A,Tiong HY

更新日期：2017-05-01 00:00:00

abstract：:The aim of this study was to determine whether patients with end-stage kidney disease (ESKD) on hemodialysis (HD) undergoing kidney transplant evaluation are at higher risk for colonic neoplasia than the general population. This is a retrospective cohort study of patients with ESKD who underwent a first screening colo...

journal_title：Clinical transplantation

authors： Saumoy M,Jesudian AB,Aden B,Serur D,Sundararajan S,Sivananthan G,Gambarin-Gelwan M

更新日期：2016-03-01 00:00:00

abstract：:In France, liver grafts which have been refused by at least five centers are proposed as rescue allocation (RA). The aim of this study is to clarify the feasibility and safety of RA grafts in liver transplantation (LT). Short- and long-term outcomes of patients who received RA grafts (RA group) were compared with thos...

journal_title：Clinical transplantation

authors： Kitano Y,Allard MA,Nakada S,Beghdadi N,Karam V,Vibert E,Sa Cunha A,Castaing D,Cherqui D,Baba H,Adam R

更新日期：2020-07-19 00:00:00

abstract：:Mycophenolate mofetil (MMF) combined with conventional cyclosporine and steroids doses efficiently prevents acute rejection in kidney transplants. However, this regimen has been associated with an increased incidence of cytomegalovirus (CMV) disease and leukopenia, specially in patients receiving MMF at 3 g/d, suggest...

journal_title：Clinical transplantation

authors： Moreso F,Serón D,Morales JM,Cruzado JM,Gil-Vernet S,Pérez JL,Fulladosa X,Andrés A,Grinyó JM

更新日期：1998-06-01 00:00:00

abstract：:Acute renal failure (ARF) is a common and severe complication after liver transplantation (LT). The aim of this study was to ascertain the impact of ARF requiring dialysis in the outcome of LT and to analyze the risk factors leading to this event in the early post-operative period. From October 1988 to December 1994, ...

journal_title：Clinical transplantation

authors： Bilbao I,Charco R,Balsells J,Lazaro JL,Hidalgo E,Llopart L,Murio E,Margarit C

更新日期：1998-04-01 00:00:00

abstract：:Anti-Xa monitoring for low molecular weight heparin (LMWH) is currently recommended in obese, renally impaired, and pregnant patients. Substantial evidence indicates that solid organ transplant (SOT) patients are at an increased risk of renal impairment, thus representing a population at risk of LMWH accumulation. The...

journal_title：Clinical transplantation

authors： Moten MA,Gaber AO,Putney D,Patel SJ

更新日期：2013-11-01 00:00:00

abstract：:Haploidentical stem cell transplantation (SCT) is increasingly used to treat pediatric patients with malignant or nonmalignant hematological disorders. The CD34+ dose of bone marrow or peripheral blood stem cells (PBSCs) has been shown to be an important determinant of the transplant outcome in adults under various pr...

journal_title：Clinical transplantation

authors： Chen Y,Xu LP,Liu KY,Chen H,Chen YH,Zhang XH,Wang Y,Wang FR,Han W,Wang JZ,Yan CH,Huang XJ

更新日期：2017-02-01 00:00:00

abstract：:Use of C(2) monitoring for cyclosporine A (CsA) microemulsion results in improved clinical outcomes vs. trough (C(0)) monitoring. Logistical issues include accurate timing of the C(2) sample; requirement for sample dilution with most standard assay techniques; and inconvenience for patients. Recently, it has been show...

journal_title：Clinical transplantation

authors： Yonan N,Martyszczuk R,Machaal A,Baynes A,Keevil BG

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Although liver transplantation may potentially cure hepatocellular carcinoma (HCC), the risk of HCC recurrence is 8%-20% at five years post-transplant. Pre-transplant alpha-fetoprotein (AFP) is a predictor of HCC recurrence, but it is unknown if pre-transplant AFP also predicts survival in patients with recu...

journal_title：Clinical transplantation

authors： Mahmud N,John B,Taddei TH,Goldberg DS

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The benefits of pancreas transplantation are often difficult to measure. Here, we sought to determine the difference in quality of life for diabetic patients with and without a functional pancreas transplant alone (PTA). METHODS:Pancreas transplant alone cases from 1993 to 2015 were considered. An IRB-appro...

journal_title：Clinical transplantation

authors： Scalea JR,Pettinato L,Fiscella B,Bartosic A,Piedmonte A,Paran J,Todi N,Siskind EJ,Bartlett ST

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Thrombosis of the pancreas after transplantation is the most common cause of relaparotomy and resultant graft loss. There is currently no standard protocol consistently proven to prevent thrombosis following transplantation. Our objective was to determine whether our protocol of post-operative low-dose int...

journal_title：Clinical transplantation

authors： Aboalsamh G,Anderson P,Al-Abbassi A,McAlister V,Luke PP,Sener A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The burden of mast cell (MC) infiltration and their phenotypes, MC-tryptase (MCT ) and MC-tryptase/chymase (MCTC ), after lung transplantation (LT) has not been evaluated in human studies. METHODS:We reviewed 20 transbronchial lung biopsy (TBLB) specimen from patients with early normal allograft (<6 months ...

journal_title：Clinical transplantation

authors： Banga A,Han Y,Wang X,Hsieh FH

更新日期：2016-07-01 00:00:00

abstract：:We have developed a practical conditioning regimen without anti-thymocyte globulin (ATG), irradiation, or other myeloablative alkylating agent for low-income countries in which patients with severe aplastic anemia (SAA), who usually have heavily transfused and a prolonged disease history. The application of ATG, Busul...

journal_title：Clinical transplantation

authors： Wang SB,Li L,Pan XH,Hu DM,Peng LH,Liu L,Xie ZJ,Yin B,Sun XJ,Yu J,Liang Y

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:Frail patients who undergo renal transplantation (RT) have more complications; however, little is known if these patients can sustain the wait to RT. We used the Timed Up and Go Test (TUGT) and Montreal Cognitive Assessment (MoCA) to determine outcomes of RT candidates. METHODS:In this retrospective study, 526...

journal_title：Clinical transplantation

authors： Bozhilov K,Vo KB,Wong LL

更新日期：2020-11-20 00:00:00

abstract：INTRODUCTION:A "new" fast track kidney allocation scheme (FTKAS) was implemented in the UK in 2012 for offering of previously declined kidneys. We evaluated the impact of the FTKAS in utilization of declined kidneys and outcome. METHODS:Adult renal transplant centers were surveyed. Overall utilization was evaluated us...

journal_title：Clinical transplantation

authors： White AD,Roberts H,Ecuyer C,Brady K,Pathak S,Clark B,Hostert LH,Attia MS,Wellberry-Smith M,Hudson A,Ahmad N

更新日期：2015-10-01 00:00:00

abstract：:From December 1999 to January 2002, 50 right lobe living donor liver transplantations were performed. The donor operations included an intraoperative cholangiography to elicit variations in bile duct anatomy. The biliary reconstruction was done whenever possible as an end-to-end microanastomosis of the donor right hep...

journal_title：Clinical transplantation

authors： Settmacher U,Steinmüller TH,Schmidt SC,Heise M,Pascher A,Theruvath T,Hintze R,Neuhaus P

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:In an effort to increase organ donation, the Department of Health and Human Services issued the Final Rule in 1998. The Health Care Financing Administration (HCFA) later required hospitals to notify organ procurement organizations (OPO) of all deaths and imminent deaths in order to remain eligible for Medica...

journal_title：Clinical transplantation

authors： Higashigawa KH,Carroll C,Wong LL,Wong LM

更新日期：2002-06-01 00:00:00

abstract：:We aimed to determine the epidemiology, risk factors, and impact of bacterial infection on pancreatic function after pancreas transplantation. Data for pancreas transplant recipients were retrospectively reviewed between 2000 and 2014 for at least 1 year. We collected and analyzed post-transplant data for bacterial in...

journal_title：Clinical transplantation

authors： Bodro M,Ferrer J,Ricart MJ,Sanclemente G,Linares L,Cervera C,Cofan F,Ventura-Aguiar P,Lopez-Boado MÁ,Marco F,Fuster J,García-Valdecasas JC,Moreno A

更新日期：2018-08-01 00:00:00

abstract：:Solid organ transplant recipients are at increased risk of developing several human papillomavirus (HPV)-related malignancies, including cervical and anal cancers. The purpose of this prospective study was to assess the initial prevalence and risk factors for high-risk HPV (HR-HPV) cervical infections in liver transpl...

journal_title：Clinical transplantation

authors： Grąt K,Grąt M,Wronka KM,Pietrzak B,Suchońska B,Walter de Walthoffen S,Młynarczyk G,Krawczyk M,Wielgoś M

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Abnormalities of renal function with long-term implications can persist after acute tubular necrosis (ATN), probably because of permanent loss of nephrons. Residual areas of fibrosis are also observed in the renal cortex post-ATN. In this study, we investigate the interstitial alterations post-ATN using hist...

journal_title：Clinical transplantation

authors： Moyses Neto M,Costa RS,Volpini RA,Garcia TM,Rodrigues FF,Coimbra TM

更新日期：2004-04-01 00:00:00

abstract：:Kidney outcomes in early post-liver transplantation (LT) are crucial for long-term prognosis, but difficult to predict. Among 203 adult LT patients, we studied the value of plasma neutrophil gelatinase-associated lipocalin (NGAL) measured pre-LT for predicting acute kidney injury (AKI), kidney-replacement therapy with...

journal_title：Clinical transplantation

authors： Aberg F,Lempinen M,Hollmén M,Nordin A,Mäkisalo H,Isoniemi H

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Arterial stiffness and left ventricular hypertrophy (LVH) are major independent risk factors for cardiovascular disease in healthy and renal population. In this study, we aimed to investigate comparative long-term effects of renal transplantation (RTx) and of hemodialysis (HD) on both arterial stiffness and ...

journal_title：Clinical transplantation

authors： Keven K,Calayoglu R,Sengul S,Dincer I,Kutlay S,Erturk S,Erbay B,Nergizoglu G

更新日期：2008-05-01 00:00:00

abstract：:Although risk factors for failure of renal retransplants have been well studied, the impact of allograft nephrectomy on subsequent renal transplantation in the cyclosporin era is not well defined. The purpose of this study is to define the effect of nephrectomy of the primary allograft on subsequent allograft survival...

journal_title：Clinical transplantation

authors： Douzdjian V,Rice JC,Carson RW,Gugliuzza KK,Fish JC

更新日期：1996-04-01 00:00:00

abstract：:Although steroid avoidance and withdrawal in renal transplant recipients (RTR) are actively being evaluated by physicians, the attitudes of recipients toward steroid use have not been systematically studied in the modern era. We conducted a confidential written survey of single-organ adult RTR pertaining to prednisone...

journal_title：Clinical transplantation

authors： Prasad GV,Nash MM,McFarlane PA,Zaltzman JS

更新日期：2003-04-01 00:00:00

abstract：:Management of transplant patients receiving cyclosporine therapy is complicated by interpatient and intrapatient variability in pharmacokinetic parameters caused by the drug's unpredictable bioavailability. Cyclosporine, a highly lipophilic cyclic polypeptide, has recently been reformulated using a microemulsion deliv...

journal_title：Clinical transplantation

authors： Ritschel WA

更新日期：1996-08-01 00:00:00

abstract：:Whole pancreas and islet cell transplantation are both reliant upon the procurement and preservation of a high quality donor pancreas for a successful outcome. In the climate of a reducing donor pool it is imperative that donor optimization, meticulous surgical retrieval and evidence based methods of preservation are ...

journal_title：Clinical transplantation

authors： Ridgway D,Manas D,Shaw J,White S

更新日期：2010-01-01 00:00:00