Microemulsion technology in the reformulation of cyclosporine: the reason behind the pharmacokinetic properties of Neoral.

abstract：:Flow cytometry crossmatch (FCXM) is a more sensitive technique than classical complement-dependent cytotoxicity (CDC) for the detection of donor-directed antibody before renal transplantation. Nevertheless, the role of FCXM in predicting long-term survival of kidney grafts is still unclear. The purpose of our study wa...

journal_title：Clinical transplantation

authors： Rebibou JM,Bittencourt MC,Saint-Hillier Y,Chabod J,Dupont I,Bittard H,Chalopin JM,Hervé P,Tiberghien P

更新日期：2004-10-01 00:00:00

abstract：:Transplantation tolerance is the ultimate goal of organ transplantation. Natural regulatory T cells (Treg) have been expected to reach clinical applications for tolerance induction because their initial description. More than ten yr later, Treg have started moving from experimental animal models into clinical applicat...

journal_title：Clinical transplantation

authors： Fritzsching E,Kunz P,Maurer B,Pöschl J,Fritzsching B

更新日期：2009-12-01 00:00:00

abstract：:Retrograde arterial flush (RGAF) of liver grafts, which prevents arterial intima injuries in living donor liver transplantation (LDLT), seemed to reduce post-transplantational cholestasis by our preliminary study. The aim of this study was to further confirm this effect of RGAF of grafts in LDLT by a prospective rando...

journal_title：Clinical transplantation

authors： Liu C,Loong CC,Hsia CY,Wang SC,Yeh YC,Lin NC,Tsai HL,Tsou MY

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Intraoperative fluid management during laparoscopic donor nephrectomy (LDN) may have a significant effect on donor and recipient outcomes. We sought to quantify variability in fluid management and investigate its impact on donor and recipient outcomes. METHODS:A retrospective review of patients who underwen...

journal_title：Clinical transplantation

authors： Williams AM,Kumar SS,Bhatti UF,Biesterveld BE,Kathawate RG,Sung RS,Woodside KJ,Englesbe MJ,Alameddine MB,Waits SA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:We aimed to develop an adapted information-motivation-behavioral skills (IMB) model to describe barriers and facilitators for adherence and self-management among kidney transplant recipients. METHODS:We conducted a review of literature about kidney transplant recipients' knowledge, perceptions, and experien...

journal_title：Clinical transplantation

authors： Ranahan M,Von Visger J,Kayler LK

更新日期：2020-06-01 00:00:00

abstract：:Although FK 506 has been shown to effectively reverse refractory renal allograft rejection, its ability to reverse accelerated renal allograft rejection as a primary agent has not been specifically addressed. Herein evidence of the ability of FK 506 to reverse accelerated renal allograft rejection is presented. A 16-y...

journal_title：Clinical transplantation

authors： Woodle ES,Newell KA,Haas M,Bartosh S,Josephson MA,Millis JM,Bruce DS,Piper JB,Aronson AJ,Thistlethwaite JR

更新日期：1997-08-01 00:00:00

abstract：:The shortage of kidney donors has led to broadening of the acceptance criteria for deceased donor organs beyond the traditional use of young donors. We determined long-term post-transplant outcomes in recipients of dual expanded criteria donor kidneys (dECD, n = 44) and compared them to recipients of standard criteria...

journal_title：Clinical transplantation

authors： Salifu MO,Norin AJ,O'Mahony C,Sumrani N,Apel A,Ikram M,Alam A,Hayat A,Jindal RM,Friedman EA,Distant DA

更新日期：2009-06-01 00:00:00

abstract：:The exact mechanism of acute and chronic allograft rejection still remains unclear. The chemokine SDF-1 as mediator of allograft rejection has been under intensive investigation in liver, cardiac and bone marrow transplantation, whereas in renal transplantation, there are no reports about SDF-1 to date. This study was...

journal_title：Clinical transplantation

authors： Hoffmann U,Banas B,Krüger B,Banas M,Bergler T,Böger C,Kammerl M,Obed A,Rümmele P,Segerer S,Riegger GA,Krämer BK

更新日期：2006-11-01 00:00:00

abstract：:There is currently an imbalance between the need for cadaveric kidneys for transplantation and the supply. The medical criteria for accepting cadaveric donors are changing and organs that were originally thought to be unacceptable have functioned well. Previous reports have discussed the problems with transplanting ...

journal_title：Clinical transplantation

authors： Jacoby K,Lippman HR,Hura CE,McFarlin L,Jones CF,Banowsky LH

更新日期：1992-12-01 00:00:00

abstract：:This paper describes 108 consecutively treated patients receiving 109 cadaveric (CD) and living donor (LD) renal allografts using a protocol of quadruple sequential immunosuppression with a rabbit anti-human thymocyte IgG (Thymoglobuline), azathioprine, tapering corticosteroids, and delayed introduction of cyclosporin...

journal_title：Clinical transplantation

authors： Guttmann RD,Flemming C

更新日期：1997-06-01 00:00:00

abstract：:Simultaneous pancreas-kidney transplantation is an established procedure for patients with type I diabetes and end-stage renal disease. Continuous advances in the operation techniques with consequent reduction of perioperative morbidity and mortality and the introduction of modern immunosuppressive agents improved not...

journal_title：Clinical transplantation

authors： Schmied BM,Müller SA,Mehrabi A,Welsch T,Büchler MW,Zeier M,Schmidt J

更新日期：2006-01-01 00:00:00

abstract：:These updated guidelines from the Infectious Diseases Community of Practice of the American Society of Transplantation review the diagnosis, prevention, and management of tuberculosis in the pre- and post-transplant period. The challenges of screening for both latent and active TB in the setting of transplantation are...

journal_title：Clinical transplantation

authors： Subramanian AK,Theodoropoulos NM,Infectious Diseases Community of Practice of the American Society of Transplantation.

更新日期：2019-09-01 00:00:00

abstract：:Acute allograft glomerulopathy (AAG) characterized by hypercellularity, enlargement of endothelial cells, infiltration of glomeruli by mononuclear cells and webs of PAS-positive material has been reported as an unusual but distinct form of acute rejection in kidney transplant recipients. We present a case of persisten...

journal_title：Clinical transplantation

authors： Katafuchi R,Masutani K,Mizumasa T,Fujita E,Tanaka H,Ikeda K,Yanase T,Ando T,Fujimi S

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Stem cell-based therapy has received attention as a possible alternative to organ transplantation. The aim of this study was to assess the safety and efficacy of autologous transplantation of bone marrow (BM)-derived stromal cells in post-HCV liver cirrhosis patients. METHODOLOGY:10 × 10(6) of isolated huma...

journal_title：Clinical transplantation

authors： Amin MA,Sabry D,Rashed LA,Aref WM,el-Ghobary MA,Farhan MS,Fouad HA,Youssef YA

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Progressive familial intrahepatic cholestasis (PFIC) results in liver cirrhosis. Therefore, some PFIC patients require liver transplantation (LT). Although three types of PFIC have been identified, their etiologies include unknown mechanisms. PATIENTS:A total of 717 recipients who underwent living-donor LT ...

journal_title：Clinical transplantation

authors： Hori T,Egawa H,Takada Y,Ueda M,Oike F,Ogura Y,Sakamoto S,Kasahara M,Ogawa K,Miyagawa-Hayashino A,Yonekawa Y,Yorifuji T,Watanabe K,Doi H,Nguyen JH,Chen F,Baine AM,Gardner LB,Uemoto S

更新日期：2011-09-01 00:00:00

abstract：:Recent changes in Center for Medicare & Medicaid Services (CMS) condition for participation, using benchmark volume/outcomes requirements for certification, have been implemented. Consequently, the ability of a transplant center to assess its risk tolerance is important in successful management. An analysis of SRTR da...

journal_title：Clinical transplantation

authors： Johnson SR,Karp SJ,Curry MP,Barugel M,Rodrigue JR,Mandelbrot DA,Rogers CP,Hanto DW

更新日期：2012-05-01 00:00:00

abstract：INTRODUCTION:Thrombosis of the pancreas after transplantation is the most common cause of relaparotomy and resultant graft loss. There is currently no standard protocol consistently proven to prevent thrombosis following transplantation. Our objective was to determine whether our protocol of post-operative low-dose int...

journal_title：Clinical transplantation

authors： Aboalsamh G,Anderson P,Al-Abbassi A,McAlister V,Luke PP,Sener A

更新日期：2016-09-01 00:00:00

abstract：:With increasing shortage of donor organs and changes in organ allocation systems, there is a considerable need for alternative or supportive techniques in the field of liver transplantation. Liver cell transplantation (LCT) is such an innovative technique that is especially promising for use in children, because it is...

journal_title：Clinical transplantation

authors： Meyburg J,Schmidt J,Hoffmann GF

更新日期：2009-12-01 00:00:00

abstract：:Living-related liver transplantation (LRLT) in pediatric recipients has been successful with 90% 1-year survival (1, 2). LRLT in adults is yet to succeed. We hypothesize a management strategy based on the donor graft weight-to-recipient body weight ratio (GRBWR) and the Redox Tolerance Index (RTI) (3). Favorable recip...

journal_title：Clinical transplantation

authors： Habib N,Tanaka K

更新日期：1995-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) is currently the leading indication worldwide for orthotopic liver transplantation. However, the majority of patients receiving transplant for HCV eventually develop histopathologic evidence of recurrent allograft HCV and approximately 10% die or require retransplantation within the first 5 pos...

journal_title：Clinical transplantation

authors： Leung JY,Abraczinskas DR,Bhan AK,Terella AM,Pascual M,Cosimi AB,Chung RT

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Tracheostomy is an important adjunct for lung transplant patients requiring prolonged ventilation. We explored the effects of post-transplant tracheostomy on survival and bronchiolitis obliterans syndrome after lung transplant. METHODS:A retrospective, single center analysis was performed on all lung transp...

journal_title：Clinical transplantation

authors： Huddleston SJ,Brown R,Rudser K,Goswami U,Tomic R,Lemke NT,Shaffer AW,Soule M,Hertz M,Shumway S,Kelly R,Loor G

更新日期：2020-01-01 00:00:00

abstract：:Obese transplant recipients (BMI ≥ 30 kg/m2 ) have decreased posttransplant patient and graft survival compared with their nonobese counterparts. At the same time, many prednisone-related side effects (eg, new-onset diabetes) are similar to those associated with obesity. Using SRTR data, we studied outcomes associated...

journal_title：Clinical transplantation

authors： Matas AJ,Vock DM

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Liver transplantation with livers grafts from elderly donors has been associated with a higher risk of biliary complications. The aim of this study was to examine whether our national protocol could contribute to a lower incidence of biliary complications. METHODS:All adult recipients in the Netherlands tra...

journal_title：Clinical transplantation

authors： Westerkamp AC,Korkmaz KS,Bottema JT,Ringers J,Polak WG,van den Berg A,van Hoek B,Metselaar HJ,Porte RJ

更新日期：2015-07-01 00:00:00

abstract：:The current pandemic SARS-CoV-2 has required an unusual allocation of resources that can negatively impact chronically ill patients and high-complexity procedures. Across the European Reference Network on Pediatric Transplantation (ERN TransplantChild), we conducted a survey to investigate the impact of the COVID-19 o...

journal_title：Clinical transplantation

authors： Doná D,Torres Canizales J,Benetti E,Cananzi M,De Corti F,Calore E,Hierro L,Ramos Boluda E,Melgosa Hijosa M,Garcia Guereta L,Pérez Martínez A,Barrios M,Costa Reis P,Teixeira A,Lopes MF,Kaliciński P,Branchereau S,Boyer O

更新日期：2020-10-01 00:00:00

abstract：:This study evaluated the efficacy of primary endovascular stenting in cases of transplant renal artery stenosis (TRAS) from cadaver and non-heart-beating donor kidneys. Patients with TRAS (n = 13) from a single-centre transplant population (n = 476) were treated by primary percutaneous angioplasty and endovascular ste...

journal_title：Clinical transplantation

authors： Ridgway D,White SA,Nixon M,Carr S,Blanchard K,Nicholson ML

更新日期：2006-05-01 00:00:00

abstract：:The organ shortage is one of the major challenges in the field of organ transplantation, yet the percentage of kidneys procured and discarded prior to transplantation has continued to rise to twenty percent. The causes of organ discard are complex, yet an urgent need exists for collaborative efforts to maximize the ut...

journal_title：Clinical transplantation

authors： Cooper M,Formica R,Friedewald J,Hirose R,O'Connor K,Mohan S,Schold J,Axelrod D,Pastan S

更新日期：2019-01-01 00:00:00

abstract：:Acute renal failure (ARF) is a common and severe complication after liver transplantation (LT). The aim of this study was to ascertain the impact of ARF requiring dialysis in the outcome of LT and to analyze the risk factors leading to this event in the early post-operative period. From October 1988 to December 1994, ...

journal_title：Clinical transplantation

authors： Bilbao I,Charco R,Balsells J,Lazaro JL,Hidalgo E,Llopart L,Murio E,Margarit C

更新日期：1998-04-01 00:00:00

abstract：:Experimental models suggest that endothelin-1 (ET-1) has a significant role in the pathogenesis of cyclosporin A (CyA)-induced hypertension. However, its serum levels evaluated in different studies, including patients who received solid organ transplants, exhibited controversial results. Our study population consisted...

journal_title：Clinical transplantation

authors： Cauduro RL,Costa C,Lhulier F,Garcia RG,Cabral RD,Gonçalves LF,Manfro RC

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:It has been shown that glomerulonephritis (GN) recurrence affects graft survival more than acute rejection. Thus, we assessed allograft survival after biopsy-confirmed diagnosis of acute rejection or recurrent GN in current era of immunosuppression. METHODS:Allograft survival following a biopsy diagnosis of...

journal_title：Clinical transplantation

authors： Singh T,Astor BC,Zhong W,Mandelbrot DA,Maursetter L,Panzer SE

更新日期：2019-12-01 00:00:00

abstract：:The purpose of this study was to compare CsA dose monitoring with trough levels (T0) vs. levels obtained 6 h after the morning dose of CsA (T6), with respect to the incidence of acute rejection and renal dysfunction, and the cumulative dose, as well as the cost of CsA after heart transplantation. Twenty consecutive ad...

journal_title：Clinical transplantation

authors： Cantarovich M,Besner JG,Fitchett DH,Latter DA

更新日期：1997-10-01 00:00:00