Immunosuppressive standards in simultaneous kidney-pancreas transplantation.

Abstract:

:Simultaneous pancreas-kidney transplantation is an established procedure for patients with type I diabetes and end-stage renal disease. Continuous advances in the operation techniques with consequent reduction of perioperative morbidity and mortality and the introduction of modern immunosuppressive agents improved not only patients but also graft survival and significantly decreased rejection episodes of both kidney and pancreas grafts. Availability of a variety of new immunosuppressants in the clinical routine and increasing experience of the transplant specialists allowed further developments of therapeutic schemes with application of induction and maintenance immunosuppressive protocols. In this article, we summarize the current status of immunosuppressive regimens in simultaneous pancreas and kidney transplantation.

journal_name

Clin Transplant

journal_title

Clinical transplantation

authors

Schmied BM,Müller SA,Mehrabi A,Welsch T,Büchler MW,Zeier M,Schmidt J

doi

10.1111/j.1399-0012.2006.00599.x

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

44-50

eissn

0902-0063

issn

1399-0012

pii

CTR599

journal_volume

20 Suppl 17

pub_type

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