当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Isolation and identification of human brain natriuretic peptides in cardiac atrium.

Isolation and identification of human brain natriuretic peptides in cardiac atrium.

Abstract：

:By using a radioimmunoassay (RIA) system newly established for human brain natriuretic peptide (BNP), a high concentration of immunoreactive (ir-) human BNP (hBNP) has been found in cardiac atrium (1). Two molecular forms of ir-hBNP of 4K and 13-15K were isolated from atrial extracts by using anti-hBNP IgG immunoaffinity chromatography and reverse phase high performance liquid chromatography (HPLC). By microsequencing, the peptides were determined to be a pro-hBNP (gamma-hBNP) and its C-terminal 32-amino acid peptide (hBNP-32). Based on these results, in cardiac atrium, hBNP is found to be processed in a pathway similar to that of porcine BNP (pBNP) but distinct from that of rat BNP, although low MW hBNP-32 is a major form in contrast to pBNP which exists as a high MW gamma-pBNP.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Hino J,Tateyama H,Minamino N,Kangawa K,Matsuo H

doi

10.1016/0006-291x(90)92081-a

subject

Has Abstract

pub_date

1990-03-16 00:00:00

pages

693-700

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(90)92081-A

journal_volume

167

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Fluorescence polarization study of lipids and membranes prepared from brain hemispheres of a hibernating mammal.

    abstract：:The physical behavior of total lipids, microsomes and microsomal lipids prepared from brain hemispheres of European Hamsters (Cricetus cricetus) was approached by the measure of the fluorescence polarization of the probe 1,6-diphenyl 1,3,5-hexatriene. We compare in this study the results obtained for two critical peri...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(84)91665-6

    authors： Montaudon D,Robert J,Canguilhem B

    更新日期：1984-02-29 00:00:00

  • The effect of epinephrine on the intracellular free calcium of parent and Ki-ras-transfected NIH3T3 cells.

    abstract：:Here we describe differences in the formation of the epinephrine-induced Ca2+ transients between parent and Ki-ras-transformed NIH3T3 fibroblasts. These transients proved to be the results of an efflux from both the thapsigargin-sensitive and -insensitive intracellular pools. While the epinephrine-induced detachment o...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1055

    authors： Tóth S,Fu T,Nozawa Y,Csaba G

    更新日期：1993-01-29 00:00:00

  • Metformin inhibition of mTORC1 activation, DNA synthesis and proliferation in pancreatic cancer cells: dependence on glucose concentration and role of AMPK.

    abstract：:Metformin, a widely used anti-diabetic drug, is emerging as a potential anticancer agent but the mechanisms involved remain incompletely understood. Here, we demonstrate that the potency of metformin induced AMPK activation, as shown by the phosphorylation of its substrates acetyl-CoA carboxylase (ACC) at Ser(79) and ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.11.010

    authors： Sinnett-Smith J,Kisfalvi K,Kui R,Rozengurt E

    更新日期：2013-01-04 00:00:00

  • Similar physical and kinetic properties of rat brain synaptic membrane and cytosol phosphoinositide phospholipases C.

    abstract：:Phosphoinositide phospholipase C (PLC) was extracted from the synaptic membrane fraction of rat brain by 1% sodium deoxycholate. The molecular weight and sedimentation coefficient of the membrane PLC were about 160,000 and 6.7 as estimated by gel filtration and sucrose density gradient centrifugation, respectively. Th...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91309-x

    authors： Kozawa O,Hoshijima M,Tanimoto T,Ohmori T,Takai Y

    更新日期：1987-05-29 00:00:00

  • Inhibitors of protein phosphatases 1 and 2A differentially prevent intrinsic and extrinsic apoptosis pathways.

    abstract：:Inhibitors of serine/threonine protein phosphatases can inhibit apoptosis. We investigated which protein phosphatases are critical for this protection using calyculin A, okadaic acid, and tautomycin. All three phosphatase inhibitors prevented anisomycin-induced apoptosis in leukemia cell models. In vitro, calyculin A ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.09.003

    authors： Chatfield K,Eastman A

    更新日期：2004-10-29 00:00:00

  • Virosomes reconstituted from human immunodeficiency virus proteins and lipids.

    abstract：:Purified Human Immunodeficiency Virus (HIV) was solubilized in octylglucopyranoside. After centrifugation, the supernatant was added to lipid-detergent mixed micelles. Formation of virosomes occurred during overnight dialysis. Centrifugation on a continuous glycerol gradient showed that envelope glycoproteins (gp120 a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)91754-g

    authors： Cornet B,Vandenbranden M,Cogniaux J,Giurgea L,Dekegel D,Ruysschaert JM

    更新日期：1990-02-28 00:00:00

  • Ntg2 of Saccharomyces cerevisiae repairs the oxidation products of 8-hydroxyguanine.

    abstract：:In Escherichia coli, endonuclease III (endo III) repairs the oxidation products of 8-OHGua. However, the corresponding repair enzymes in eukaryotes have not been identified. Here we report that 8-hydroxyguanine (8-OHGua) is highly sensitive to further oxidation. We also show that Ntg2, a functional homolog of endo III...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.5305

    authors： Kim JE,You HJ,Choi JY,Doetsch PW,Kim JS,Chung MH

    更新日期：2001-08-03 00:00:00

  • Cleavage of DNA by N-phosphoryl histidine.

    abstract：:DNA cleavage by N-(O,O-diisopropyl)phosphoryl histidine(DIPP-His) is investigated by a submarine agarose electrophoresis technique. It was found that DIPP-His could cleave supercoiled DNAs and lambda DNA without the participation of divalent metal ions, while the histidine itself and N-(O,O-diisopropyl)phosphoryl alan...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.2210

    authors： Li Y,Sha YW,Ma Y,Zhao Y

    更新日期：1995-08-24 00:00:00

  • Purification and polymerization properties of two lethal yeast actin mutants.

    abstract：:The budding yeast Saccharomyces cerevisiae contains a single actin gene and the gene product, actin, is essential for growth. Two mutants of yeast actin that do not support yeast growth were prepared from yeast by coexpressing the mutant and a 6-histidine-tagged wild-type actin followed by separation of the wild-type ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.2650

    authors： Frieden C,Du J,Schriefer L,Buzan J

    更新日期：2000-05-10 00:00:00

  • Androgen receptor regulates cardiac fibrosis in mice with experimental autoimmune myocarditis by increasing microRNA-125b expression.

    abstract：:Cardiac fibrosis is an important cardiac remodeling event in the development of inflammation dilated cardiomyopathy （iDCM）. We have previously observed that degradation enhancer of androgen receptor (ASC-J9®) could improve cardiac inflammation and fibrosis. Using Primary CFs, we demonstrated that ASC-J9® attenuates th...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.09.092

    authors： Wang Y,Ma W,Lu S,Yan L,Hu F,Wang Z,Cheng B

    更新日期：2018-11-17 00:00:00

  • Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.

    abstract：:Curcumin, a component of turmeric (Curcuma longa), has been reported to suppress beta-catenin response transcription (CRT), which is aberrantly activated in colorectal cancer. However, the effects of its natural analogs (demethoxycurcumin [DMC] and bisdemethoxycurcumin [BDMC]) and metabolite (tetrahydrocurcumin [THC])...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.10.171

    authors： Ryu MJ,Cho M,Song JY,Yun YS,Choi IW,Kim DE,Park BS,Oh S

    更新日期：2008-12-26 00:00:00

  • Minimal translation of the tmRNA tag-coding region is required for ribosome release.

    abstract：:The trans-translation system in bacteria promotes recycling of stalled ribosomes and targets incomplete peptides for proteolysis. In Escherichia coli, loss of trans-translation function has little effect on growth under normal laboratory conditions. Among the subtle phenotypes of tmRNA-deficient mutants is the inabili...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.03.142

    authors： O'Connor M

    更新日期：2007-05-25 00:00:00

  • Down-regulation of TRAF4 targeting RSK4 inhibits proliferation, invasion and metastasis in breast cancer xenografts.

    abstract：:Ribosomal S6 protein kinase 4 (RSK4) was known as a novel tumor suppressor gene, and the tumor necrosis factor receptor-associated factor 4 (TRAF4) was linked to carcinogenesis. The purpose of this study is to further investigate the effect of the TRAF4 gene on cell proliferation, invasion and metastasis in vivo and e...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.04.164

    authors： Zhu L,Zhang S,Huan X,Mei Y,Yang H

    更新日期：2018-06-07 00:00:00

  • IFN-gamma acts as anti-angiogenic cytokine in the human cornea by regulating the expression of VEGF-A and sVEGF-R1.

    abstract：:Inflammatory processes within the cornea are known to be associated with corneal neovascularization (CN). We examined the effects of inflammatory mediators on the expression of angiogenic factors by corneal cells. TNF-alpha and IL-1 induced VEGF-A secretion by corneal fibroblasts (HCRF) and this was inhibited signific...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.07.042

    authors： Kommineni VK,Nagineni CN,William A,Detrick B,Hooks JJ

    更新日期：2008-09-26 00:00:00

  • Inactivation of tyrosinase photoinduced by pterin.

    abstract：:Tyrosinase catalyzes in mammals the first and rate-limiting step in the biosynthesis of the melanin, the main pigment of the skin. Pterins, heterocyclic compounds able to photoinduce oxidation of DNA and its components, accumulate in the skin of patients suffering from vitiligo, a chronic depigmentation disorder in wh...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.06.155

    authors： Laura Dántola M,Gojanovich AD,Thomas AH

    更新日期：2012-08-03 00:00:00

  • Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse.

    abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease, whose primary mechanisms or causes are still not defined and for which no effective treatment is available. We have recently reported that before disease onset the level of tyrosine nitrated proteins is increased in the G93A SOD1 transgenic mouse mod...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.12.075

    authors： Massignan T,Casoni F,Basso M,Stefanazzi P,Biasini E,Tortarolo M,Salmona M,Gianazza E,Bendotti C,Bonetto V

    更新日期：2007-02-16 00:00:00

  • Identification of a major bovine heart Ca2+ binding protein.

    abstract：:The 100,000 x g supernatant of bovine heart has been chromatographed on DEAE-cellulose and the resultant fractions have been analyzed for both calcium binding activity and calmodulin activity. Of the four peaks of calcium binding activity detected by this procedure only a single peak (peak IV) was identified as calmod...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(86)80032-8

    authors： Waisman DM,Khanna NC,Tokuda M

    更新日期：1986-09-14 00:00:00

  • Nucleoside triphosphate binding and hydrolysis by histone H1.

    abstract：:We present here further evidence supporting that histone H1 contains a nucleotide binding site interacting e.g. with ADP, ATP, GDP and GTP. The finding is in accordance with the previous observation that nucleotides modulate recognition of DNA by H1. Most interestingly, H1 appears to be capable of hydrolyzing NTPs and...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80146-9

    authors： Mannermaa RM,Oikarinen J

    更新日期：1992-01-15 00:00:00

  • Crystallization and some properties of acetylpolyamine amidohydrolase from Mycoplana bullata.

    abstract：:During the course of investigations on the catabolism of acetylpolyamines by microorganisms, we found that acetylpolyamine amidohydrolase was produced by Mycoplana bullata FERM BP-1845 and isolated the enzyme from the cell-free extract in crystalline form. The enzyme had an apparent molecular weight of 67 kDa and was ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80997-5

    authors： Fujishiro K,Ando M,Uwajima T

    更新日期：1988-12-30 00:00:00

  • Analysis of tamoxifen-DNA adducts by high-performance liquid chromatography using postcolumn online photochemical activation.

    abstract：:Tamoxifen, a widely used nonsteroidal antiestrogen in the treatment of breast cancer, forms several metabolites. 4-Hydroxytamoxifen (4-OHTam), a metabolite found in the bloodstream, has much higher affinity for the estrogen receptor than tamoxifen itself. Oxidative activation of 4-OHTam induces DNA damage. DNA isolate...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.2896

    authors： Sharma M

    更新日期：2000-06-24 00:00:00

  • Structural modeling of SoxF protein from Chlorobium tepidum: an approach to understand the molecular basis of thiosulfate oxidation.

    abstract：:Microbial redox reactions of inorganic sulfur compounds play a vital role in balancing the turnover of this element in the environment. These vital reactions are carried out by the enzyme system encoded by the sox operon. The central player of the sulfur oxidation biochemistry is the SoxY-Z protein complex. Another pr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.09.101

    authors： Bagchi A

    更新日期：2011-10-22 00:00:00

  • In-house made nucleofection buffer for efficient and cost effective transfection of RAW 264.7 macrophages.

    abstract：:Electroporation is the most widely employed method of gene transfer into macrophages which are hard to transfect. RAW 264.7 is a widely used cell line for studying macrophage responses. Electroporation of RAW 264.7 cells with commercial reagents although very efficient is expensive necessitating the development of cos...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.04.043

    authors： Alamuru-Yellapragada NP,Kapadia B,Parsa KVL

    更新日期：2017-05-27 00:00:00

  • A role for DIS3L2 over natural nonsense-mediated mRNA decay targets in human cells.

    abstract：:The nonsense-mediated decay (NMD) pathway selectively degrades mRNAs carrying a premature translation-termination codon but also regulates the abundance of a large number of physiological mRNAs that encode full-length proteins. In human cells, NMD-targeted mRNAs are degraded by endonucleolytic cleavage and exonucleoly...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.08.105

    authors： da Costa PJ,Menezes J,Saramago M,García-Moreno JF,Santos HA,Gama-Carvalho M,Arraiano CM,Viegas SC,Romão L

    更新日期：2019-10-22 00:00:00

  • Purification and properties of 4-hydroxyphenylacetic acid 3-hydroxylase from Pseudomonas putida.

    abstract：:4-Hydroxyphenylacetic acid 3-hydroxylase is a key enzyme in the pathway for the microbial degradation of phenylalanine, tyrosine and many aromatic amines. This enzyme was purified to homogeneity from Pseudomonas putida by affinity chromatography. The protein had a molecular weight of 91,000 and was a dimer of identica...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(88)90173-8

    authors： Raju SG,Kamath AV,Vaidyanathan CS

    更新日期：1988-07-29 00:00:00

  • Mice lacking DUSP6/8 have enhanced ERK1/2 activity and resistance to diet-induced obesity.

    abstract：:Extracellular signal-regulated kinase 1 and 2 (ERK1/2) have been implicated as important regulators of metabolic homeostasis. Here we generated a new mouse model with genetic deletion of two ERK1/2 phosphatases, dual specificity phosphatase (DUSP) 6 and 8, to further define the role of ERK1/2 in obesity development. D...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.08.106

    authors： Liu R,Peters M,Urban N,Knowlton J,Napierala T,Gabrysiak J

    更新日期：2020-11-26 00:00:00

  • Activated nuclear transcription factor kappaB in patients with myocarditis and dilated cardiomyopathy--relation to inflammation and cardiac function.

    abstract：OBJECTIVES AND BACKGROUND:Myocarditis is caused by various agents and autoimmune processes. It is unknown whether viral genome persistence represents inactive remnants of previous infections or whether it is attributed to ongoing adverse processes. The latter also applies to the course of autoimmune myocarditis. One pr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.10.195

    authors： Alter P,Rupp H,Maisch B

    更新日期：2006-01-06 00:00:00

  • Identification of novel single-stranded DNA binding proteins recognizing octamer motif.

    abstract：:We have previously identified the region containing transcriptional enhancer in mouse immunoglobulin heavy chain (IgH) gene as an initiation region of DNA replication. The octamer sequence therein has been found to be essential for initiation of DNA replication as well as for transcription. Octamer-binding protein fam...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.1593

    authors： Ogawa N,Ariga H,Iguchi-Ariga SM

    更新日期：1994-05-16 00:00:00

  • Circadian expression of clock genes in human peripheral leukocytes.

    abstract：:In mammals, behavioral and physiological processes display 24-h rhythms that are regulated by a circadian system. In the present study, we investigated the possibility that the expression of clock genes in peripheral leukocytes can be used to assess the circadian clock system. We found that Per1 and Per2 exhibit circa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.01.063

    authors： Fukuya H,Emoto N,Nonaka H,Yagita K,Okamura H,Yokoyama M

    更新日期：2007-03-23 00:00:00

  • Oligonucleotide-capped gold nanoparticles for improved atomic force microscopic imaging and enhanced selectivity in polynucleotide detection.

    abstract：:A novel assay for selective determination of polynucleotides using atomic force microscopy in conjunction with the formation of the probe/target/DNA-gold nanoparticle sandwich structure at a gold surface is described. A 17-mer probe was attached to the surface for subsequent hybridization with a polynucleotide target....

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3943

    authors： Han S,Lin J,Zhou F,Vellanoweth RL

    更新日期：2000-12-09 00:00:00

  • Sequence homology between prokaryotic and eukaryotic forms of serine hydroxymethyltransferase.

    abstract：:The sequence of tryptic and chymotryptic peptides from cytosolic and mitochondrial rabbit liver serine hydroxymethyltransferase are compared to the proposed sequence of a protein coded for by the glyA gene of Escherichia coli. The E. coli glyA gene is believed to code for serine hydroxymethyltransferase. Extensive seq...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(83)80242-3

    authors： Barra D,Martini F,Angelaccio S,Bossa F,Gavilanes F,Peterson D,Bullis B,Schirch L

    更新日期：1983-11-15 00:00:00