Abstract:
:The purpose of this randomized controlled trial was to determine the effects of an 8-week (aerobic+strength) exercise training program (3 sessions/week) on the circulating cytokine levels of breast cancer survivors. We randomly allocated 16 female survivors of breast cancer (mean±SD age: 50±5 years) to an intervention or usual care (control) group (N=8 in each group). The intervention group followed an 8-week exercise program consisting of 3 sessions/week (session duration: 90 min). We measured the levels of the following cytokines before and after the intervention: beta-NGF, CTACK, eotaxin, FGF basic, G-CSF, gmCSFα, HGF, ICAM1, IFNα2, IFNγ, IL1α, IL1ß, IL1ra, IL2, IL2ra, IL3, IL4, IL6, IL7, IL8, IL9, IL10, IL12, IL13, IL15, IL16, IL17, IL18, IP10, LIF, MCS-F, MIP1α, MIP1β, MIF, MCP1, MCP3, MIG, PDGF bb, SCF, SCGFβ, SDF1α, TRAIL, TNFα, TNFβ, VCAM1, and VEGF. We only observed a significant interaction (group*time) effect for CTACK ( P=0.016), with mean values remaining stable in the intervention group but increasing over time in controls. The intervention program did not induce a significant decrease in the main breast cancer-related cytokines such as IL6 and IL8. A combined (aerobic+strength) 8-week exercise training intervention did not induce major changes in the basal cytokine levels of breast cancer survivors.
journal_name
Int J Sports Medjournal_title
International journal of sports medicineauthors
Gómez AM,Martínez C,Fiuza-Luces C,Herrero F,Pérez M,Madero L,Ruiz JR,Lucia A,Ramírez Mdoi
10.1055/s-0031-1271697subject
Has Abstractpub_date
2011-06-01 00:00:00pages
461-7issue
6eissn
0172-4622issn
1439-3964journal_volume
32pub_type
杂志文章,随机对照试验abstract::Highly repetitive submaximal intermittent contractions of the forearm muscles during periods of 30-50 min partially explain why motorcycle races are so demanding for the neuromuscular system. This study investigated the contribution of central and peripheral mechanisms of fatigue on the exerted and contralateral exten...
journal_title:International journal of sports medicine
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doi:10.1055/s-0035-1549959
更新日期:2015-11-01 00:00:00
abstract::The present series of experiments were conducted to access the surface EMG frequency parameters during repeated fingertip isometric contractions to determine if they can be used as a fatigue index under specific grip used in rock climbing. Electromyograms of the finger flexors and extensors were characterised in ten e...
journal_title:International journal of sports medicine
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doi:10.1055/s-2003-41174
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abstract::Mechanical efficiency of positive work (eta+) and elastic behavior of human skeletal muscles were investigated on a special sledge apparatus which allowed the use of the normal stretch-shortening cycle exercises. Twenty-five young men were investigated in a total of 92 exercise situations, in which the intensity of th...
journal_title:International journal of sports medicine
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abstract::A review of trekking deaths from 1984 to mid-1987 showed a death rate of 15/100,000 trekkers. Altitude sickness deaths accounted for 3/23 (13%) of these deaths. Recently, we followed up on our original study by compiling the number and causes of trekking deaths in Nepal from mid-1987 through 1991. The overall number o...
journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
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更新日期:2004-08-01 00:00:00
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journal_title:International journal of sports medicine
pub_type: 杂志文章
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journal_title:International journal of sports medicine
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更新日期:2011-10-01 00:00:00
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journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
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journal_title:International journal of sports medicine
pub_type: 杂志文章,随机对照试验
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journal_title:International journal of sports medicine
pub_type: 临床试验,杂志文章
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journal_title:International journal of sports medicine
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更新日期:2010-04-01 00:00:00
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journal_title:International journal of sports medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1995-04-01 00:00:00
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journal_title:International journal of sports medicine
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