Abstract:
:Mast cells in rat hearts were studied quantitatively during normal postnatal growth and in two types of cardiac hypertrophy. Normally, cardiac mast cell density in 11-12-day-old animals is very low, but increases markedly in the following 2-3 weeks to its highest values, with a subsequent decline toward adult values. At the peak of mast cell density, the percentage of mast cells in close proximity to capillaries is also highest. In adult animals, mast cell counts are significantly higher in the right ventricle than in the left. This relation is preserved even when the right ventricle is hypertrophic, as in rats born at simulated high altitude. Chronic hypertension and swimming have little effect on the mast cell density in rat hearts. Conspicuous changes in the mast cell density at the time of capillary proliferation seem to indicate a special role played by these cells in the formation of new vessels.
journal_name
Circ Resjournal_title
Circulation researchauthors
Rakusan K,Sarkar K,Turek Z,Wicker Pdoi
10.1161/01.res.66.2.511subject
Has Abstractpub_date
1990-02-01 00:00:00pages
511-6issue
2eissn
0009-7330issn
1524-4571journal_volume
66pub_type
杂志文章abstract::The structure of the mouse natriuretic peptide type-B (BNP) gene was determined by isolating and sequencing genomic clones. The mouse BNP gene was structurally similar to other natriuretic peptide genes and comprised three exons and two introns. Expression of the mouse BNP gene was found only in cardiac tissue as dete...
journal_title:Circulation research
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更新日期:1981-03-01 00:00:00
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更新日期:1986-07-01 00:00:00
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更新日期:2001-03-02 00:00:00
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pub_type: 杂志文章
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更新日期:1997-09-01 00:00:00
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更新日期:2008-05-23 00:00:00
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更新日期:2006-08-18 00:00:00
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更新日期:2014-01-03 00:00:00
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更新日期:2003-01-10 00:00:00
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更新日期:2004-03-19 00:00:00
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更新日期:2018-12-07 00:00:00
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更新日期:1976-08-01 00:00:00
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journal_title:Circulation research
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更新日期:2008-02-15 00:00:00
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journal_title:Circulation research
pub_type: 杂志文章,评审
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更新日期:2006-05-26 00:00:00
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更新日期:2004-11-26 00:00:00
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pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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pub_type: 杂志文章,收录出版
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更新日期:1995-07-01 00:00:00
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journal_title:Circulation research
pub_type: 杂志文章
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更新日期:1990-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1161/CIRCRESAHA.111.240655
更新日期:2011-04-01 00:00:00
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更新日期:2019-05-10 00:00:00