Pediatric living donor liver transplantation for biliary atresia with hepatopulmonary syndrome: the gift of a second wind.


PURPOSE:Hepatopulmonary syndrome (HPS) is a progressive, deteriorating complication of end-stage liver disease (ESLD) that occurs in 13-47% of liver transplant candidates. Although LT is the only therapeutic option for HPS, it has a high morbidity and mortality, especially in patients with severe hypoxemia before transplantation, but the course of HPS after living donor liver transplantation (LDLT), especially for biliary atresia (BA) patients is not well established. PATIENTS AND METHODS:The present study evaluated 122 patients who received an LDLT for BA and of these, 3 patients had HPS at the time of LDLT in a single-center series. RESULTS:Two patients of the HPS patients them had biliary and/or vascular complications, but they recovered uneventfully with interventional treatment. None of the patients required supplemental oxygen and had no residual cardiopulmonary abnormalities at a follow-up of more than 24 months. CONCLUSION:Although a series of three patients is too small for definitive conclusion and further investigations must be conducted, pediatric LDLT can be a favorable therapeutic option for HPS.


Pediatr Surg Int


Urahashi T,Mizuta K,Sanada Y,Umehara M,Wakiya T,Hishikawa S,Hyodo M,Sakuma Y,Fujiwara T,Yasuda Y,Kawarasaki H




Has Abstract


2011-08-01 00:00:00












  • Blunt liver trauma in children.

    abstract::Diagnostic evaluation and treatment of blunt liver trauma in children have changed essentially over the last decades. In the period between January 1975 and December 2002, a total of 45 children, 18 girls and 27 boys, between the ages of 1 and 16 years (mean 8.19) were treated for liver rupture following blunt abdomin...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Schmidt B,Schimpl G,Höllwarth ME

    更新日期:2004-12-01 00:00:00

  • Morphogenesis of the human external male genitalia.

    abstract::The morphogenesis of the external genitalia of human fetuses (16-250 mm crown-rump [CR] length, 6-26 weeks of gestation) obtained after medical termination of pregnancy were studied. Differential development (male/female) started after 50 mm CR length (9 weeks). At that time the external genitalia consisted of a cylin...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Ammini AC,Sabherwal U,Mukhopadhyay C,Vijayaraghavan M,Pandey J

    更新日期:1997-07-01 00:00:00

  • Inflammatory myofibroblastic tumor of the liver due to Mycobacterium tuberculosis in an immunocompetent girl.

    abstract::The case of a 9-year-old girl with a Mycobacterium tuberculosis inflammatory myofibroblastic tumor (IMT) of the left lobe of the liver is reported. The tumor was surgically excised and had histological features diagnostic of IMT, a positive Ziehl-Nielsen staining for acid-fast bacilli and a positive polymerase chain r...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Manolaki N,Vaos G,Zavras N,Sbokou D,Michael C,Syriopoulou V

    更新日期:2009-05-01 00:00:00

  • Embryogenesis of a sac containing a Meckel's diverticulum.

    abstract::The embryogenesis of a previously unreported mesothelial pouch containing a Meckel's diverticulum is presented. ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Khatri HL,Singh RB,Sharma R,Aggarwal N,Singh K

    更新日期:1997-07-01 00:00:00

  • Bronchogenic cyst of the right hemidiaphragm mimicking a hydatid cyst of the liver: report of the first pediatric case.

    abstract::Bronchogenic cyst (BC), which develops from abnormal budding of the tracheal diverticulum or ventral foregut, is a congenital bronchopulmonary malformation. Localization of the BC varies depending on the level of the abnormal budding. Thoracic or abdominal-sited diaphragmatic lesions are the rarest presentations of th...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Elemen L,Tugay M,Tugay S,Gürcan NI,Erkus B,Gurbuz Y

    更新日期:2008-08-01 00:00:00

  • Long-term outcomes and complications after laparoscopic-assisted anorectoplasty vs. posterior sagittal anorectoplasty for high- and intermediate-type anorectal malformation.

    abstract:PURPOSE:Laparoscopic-assisted anorectoplasty (LAARP) is a minimally invasive procedure in which the levator ani muscle is left to potentially improve postoperative fecal continence. This study aimed to retrospectively evaluate postoperative complications and long-term outcomes of fecal continence after LAARP and compar...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Tainaka T,Uchida H,Tanaka Y,Hinoki A,Shirota C,Sumida W,Yokota K,Makita S,Oshima K,Chiba K,Ishimaru T,Kawashima H

    更新日期:2018-10-01 00:00:00

  • Abdominal radiography is not necessary in children with intussusception.

    abstract:BACKGROUND:Children with intussusception require rapid and accurate diagnosis to enable timely intervention for satisfactory outcome. Ultrasonography is the recommended standard diagnostic modality; however, abdominal radiography (AR) is still used as an initial investigation. The aim of this study was to investigate t...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Tareen F,Mc Laughlin D,Cianci F,Hoare SM,Sweeney B,Mortell A,Puri P

    更新日期:2016-01-01 00:00:00

  • Critical analysis of fecal incontinence scores.

    abstract:INTRODUCTION:Objectively evaluating the lack of bowel control (fecal incontinence) continues to be a challenge. Many have attempted to measure the severity of fecal incontinence and to evaluate its impact on the quality of life by developing standardized scoring systems. Some of these systems have been validated but no...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审


    authors: Bischoff A,Bealer J,Peña A

    更新日期:2016-08-01 00:00:00

  • Roundworm obstruction of the hepatic limb of a Roux-en-Y anastomosis.

    abstract::A 7-year-old female with a type I choledochal cyst underwent an exploratory laparotomy. A Roux-en-Y choledochojejunostomy was done following cyst excision. The patient was re-explored 8 days later for an anastomotic bile leak and high fever. A round-worm was found obstructing the jejunal lumen at the porta hepatis, re...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Kasat LS,Naregal A,Jain M,Bajaj R,Borwankar SS

    更新日期:1998-09-01 00:00:00

  • Utility of PAS and β-catenin staining in histological categorisation and prediction of prognosis of hepatoblastomas.

    abstract:AIMS:The aim of this study was to assess the usefulness of PAS, β-catenin and Ki-67 in categorising hepatoblastomas (HBs) and their significance in predicting prognosis. In addition, we have also documented the various chemotherapy induced histologic changes in HBs. METHOD:In this retrospective observational study of ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Bera G,Das RN,Roy P,Ghosh R,Islam N,Mishra PK,Chatterjee U

    更新日期:2017-09-01 00:00:00

  • Extended hepatic resection with transplantation back-up for an "unresectable" tumour.

    abstract::Liver transplantation (LT) for malignancy has had disappointing long-term results due to tumour recurrence. Ex-vivo dissection and auto-transplantation have had poor results when the tumor was obstructing bile ducts. Advances in liver surgery have made extensive liver resection safer, but cases of "unresectable" tumou...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Millar AJ,Hartley P,Khan D,Spearman W,Andronikou S,Rode H

    更新日期:2001-07-01 00:00:00

  • Congenital pyloric atresia and associated anomalies.

    abstract::Congenital pyloric atresia (CPA) is a very rare condition that was first described by Calder in 1749. Commonly, CPA occurs as an isolated lesion, which has an excellent prognosis, but it can also be seen in association with other malformations, which can have a negative impact on the final outcome. The medical records...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Al-Salem AH

    更新日期:2007-06-01 00:00:00

  • The use of robotics in pediatric surgery: my initial experience.

    abstract::Robotic assisted minimal invasive surgery (RMIS) is a new resource popular in some surgical specialties but not yet in pediatric surgery. There are numerous advantages of robotic surgical technology in adult patients well documented in the literature. The purpose of this study is to define the feasibility, safety, and...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Camps JI

    更新日期:2011-09-01 00:00:00

  • The spectrum of anorectal malformations in Africa.

    abstract::Anorectal malformations (ARM) remain a significant birth defect with geographic variation in incidence, individual phenotypes and regional geographic subtypes. Although early studies indicated a low incidence in Black patients, there is a great paucity of knowledge as to the types, frequency and incidence of ARMs enco...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,多中心研究


    authors: Moore SW,Alexander A,Sidler D,Alves J,Hadley GP,Numanoglu A,Banieghbal B,Chitnis M,Birabwa-Male D,Mbuwayesango B,Hesse A,Lakhoo K

    更新日期:2008-06-01 00:00:00

  • Surgical intervention and perioperative risk factors of retroperitoneal teratomas in children: a single institution experience.

    abstract:PURPOSE:Retroperitoneal teratomas (RTs) are rare among germ cell tumors and predominantly occur in infants. RTs are often difficult to manage by perioperative management. In this study, we retrospectively reviewed our series of RTs. METHODS:Seventy patients with germ cell tumors were treated from 1989 to 2015 in our i...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Fumino S,Maniwa J,Takeuchi Y,Sakai K,Higashi M,Aoi S,Furukawa T,Kimura O,Tajiri T

    更新日期:2016-09-01 00:00:00

  • The management of an ectopic ovary in the inguinal canal: literature review and discussion.

    abstract::We report the case of a female adolescent who had an ectopic ovary in the inguinal canal without an associated hernia, a unicornuate uterus, and ipsilateral renal agenesis. The incidental discovery of the ectopic ovary and other Mullerian anomalies, as well as the surgical correction that followed, highlights importan...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审


    authors: Webb JB,Fallon SC,Lopez ME,Boswell HB,Dietrich JE,Brandt ML

    更新日期:2014-10-01 00:00:00

  • The challenges of closing an ileostomy in patients with total intestinal aganglionosis after small bowel transplant.

    abstract::We present the case of a 14-year-old male with a history of small bowel transplantation for long segment Hirschsprung's disease who underwent Duhamel ileorectal pull-through procedure. In post-transplant, the patient had no restrictions and was not TPN-dependent. To improve his quality of life, he and his family were ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Jazi FS,Sinclair TJ,Thorson CM,Castillo R,Bonham AC,Esquivel CO,Bruzoni M

    更新日期:2018-01-01 00:00:00

  • A new method for removal of metallic-ferromagnetic foreign bodies from the tracheobronchial tree.

    abstract::Foreign-body (FB) aspirations account for a reasonable percentage of respiratory emergencies in young children. Whereas 67% of aspirated FBs are of organic origin, metallic-ferromagnetic FBs are observed less frequently. We report the use of a wire with a magnetic tip fitting into the working channel of a rigid bronch...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Mayr J,Dittrich S,Triebl K

    更新日期:1997-07-01 00:00:00

  • Immunohistology of aquaporin-1 and stem cell factor-receptor in human undescended testes.

    abstract:OBJECTIVES:Both aquaporin (AQP) 1 and the stem-cell factor/C-kit system seem to have a definite role in testis function, but very few studies have been reported in humans, especially in the paediatric age group. With the present study we wanted to investigate the expression of these proteins to better delineate their r...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Nicòtina PA,Romeo C,Arena S,Impellizzeri P,Antonuccio P,Arena F,Zuccarello B,Romeo G

    更新日期:2004-04-01 00:00:00

  • Gender assignment and hormonal treatment for disorders of sexual differentiation.

    abstract:PURPOSE:To study the gender assignment and hormonal treatment advocated for disorders of sexual differentiation (DSD). METHODS:A study was done on patients who were reviewed in the Pediatric Intersex Clinic to evaluate the pattern of gender assignment and hormonal treatment advocated. RESULTS AND CONCLUSION:The patie...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Sharma S,Gupta DK

    更新日期:2008-10-01 00:00:00

  • Sibling vesicoureteral reflux in twins.

    abstract:AIM OF STUDY:Few studies have evaluated the incidence of familial vesicoureteral reflux (VUR) among multiple gestation births. The purpose of this study was to determine the incidence and characteristics of VUR in twins in a large cohort of families with VUR. METHODS:Between 1998 and 2010, data were collected on 251 f...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Giannotti G,Menezes M,Hunziker M,Puri P

    更新日期:2011-05-01 00:00:00

  • Burns (Part 2). Tops and flops using cultured epithelial autografts in children.

    abstract::The goal of this article is to review the status of cultured epithelial autografts in clinical practice with particular focus on the pediatric subset of patients. The current indications include massive deep burns (>60 - 70% total body surface area), resurfacing-type postburn scar revisions, and skin defect coverage f...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审


    authors: Meuli M,Raghunath M

    更新日期:1997-09-01 00:00:00

  • Histological assessment of bile lake formation after hepatic portoenterostomy for biliary atresia.

    abstract::Bile lakes develop after hepatic portoenterostomy in some patients with biliary atresia, and have been regarded as an indication of poor prognosis. We reported that bile lakes have no epithelium of the bile duct on their wall, and are surrounded by bile ducts; however, the mechanism of bile lake formation is little kn...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Tainaka T,Kaneko K,Nakamura S,Ono Y,Sumida W,Ando H

    更新日期:2008-03-01 00:00:00

  • Differential expression of granulocyte, macrophage, and hypoxia markers during early and late wound healing stages following transplantation of tissue-engineered skin substitutes of human origin.

    abstract:PURPOSE:Human pigmented tissue-engineered skin substitutes represent an advanced therapeutic option to treat skin defects. The inflammatory response is one of the major factors determining integration and long-term survival of such a graft in vivo. The aim of the present study was to investigate the spatiotemporal dist...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Klar AS,Böttcher-Haberzeth S,Biedermann T,Michalak K,Kisiel M,Reichmann E,Meuli M

    更新日期:2014-12-01 00:00:00

  • Rare cause of a neck mass: successful balloon embolisation of a congenital external carotid artery-internal jugular vein fistula.

    abstract::Congenital arteriovenous fistulas are a rare cause of neck mass in children, but should be considered in the differential diagnosis of paediatric patients presenting with pulsatile neck masses even when there is no history of trauma. Balloon embolisation is the treatment of choice because of the high risk of surgical ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Ahmad S,Suleman FE

    更新日期:2011-12-01 00:00:00

  • Post-chemotherapy microscopic residual prostate rhabdomyosarcoma: long-term conservative follow-up.

    abstract::In spite of advances in the treatment of childhood bladder and prostate rhabdomyosarcoma (RMS), the ability to detect minimal residual disease correlates imperfectly with the ultimate outcome. We report the long-term follow-up of a child with microscopic residual RMS after chemotherapy. The correct interpretation of t...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Chertin B,Reinus C,Koulikov D,Rosenmann E,Farkas A,Chertin B

    更新日期:2002-01-01 00:00:00

  • A review of congenital lung malformations with a simplified classification system for clinical and research use.

    abstract:PURPOSE:Congenital lung abnormalities are rare malformations increasingly detected early by prenatal ultrasound. Whether management of these frequently asymptomatic lesions should be surgical or conservative is an unresolved issue. The necessary prospective studies are limited by the absence of a widely accepted practi...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章,评审


    authors: Seear M,Townsend J,Hoepker A,Jamieson D,McFadden D,Daigneault P,Glomb W

    更新日期:2017-06-01 00:00:00

  • HsMAD2 mRNA expression may be a predictor of sensitivity to paclitaxel and survival in neuroblastoma.

    abstract:PURPOSE:We investigated the associations between hsMAD2 mRNA expression in tumor cells and sensitivity to paclitaxel or patient prognosis in neuroblastoma. METHODS:Fifty-one formalin-fixed paraffin-embedded tumor samples were manually microdissected to collect tumor cells, and RNA was purified. Nineteen clinical sampl...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Otake K,Uchida K,Tanaka K,Koike Y,Inoue M,Matsushita K,Ueeda M,Hashimoto K,Kitajima T,Komada Y,Kusunoki M

    更新日期:2011-02-01 00:00:00

  • The use of mesenchymal stem cells in bladder augmentation.

    abstract:PURPOSE:To compare integration of bladder acellular matrix (BAM) with the bladder when seeded with mesenchymal stem cells (MSC) and when MSC are injected intravenously (IV). METHODS:MSCs were isolated from bone marrow of EPM-1 Wistar male rats. Female rats were distributed into: Group A-BAM augmentation; Group B-BAM a...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Leite MT,Freitas-Filho LG,Oliveira AS,Semedo-Kuriki P,Laks M,Arias VE,Peixoto PS

    更新日期:2014-04-01 00:00:00

  • Congenital anterior urethrocutaneous fistula associated with urethral duplication.

    abstract::Congenital anterior penile urethral fistula is a rare anomaly; only seven cases have been reported to date. This report outlines the clinical presentation and the embryologic mechanism of a case associated with urethral duplication. ...

    journal_title:Pediatric surgery international

    pub_type: 杂志文章


    authors: Merrot T,Pankevych T,Chaumoitre K,Alessandrini P

    更新日期:2003-12-01 00:00:00