Abstract：
:A review of 100 consecutive cases of congenital diaphragmatic hernia (CDH) treated at our institute focusing on the efficacy of protocolized management (PM) was conducted. Of the 100 cases, 14 who became symptomatic more than 24 h after birth, and seven with fatal anomalies (four cardiac and three chromosomal) were excluded, leaving 79 subjects for this study. Of these, 41 were diagnosed prenatally (PD). Subjects were divided into four groups. Group I: No PD, no PM (n = 34), Group II: No PD, PM (n = 4), Group III: PD, no PM (n = 21), and Group IV: PD, PM (n = 20). PM includes criteria for planned delivery, use of high frequency oxygenation, nitric oxide, echocardiography (EC), and a medication schedule. Overall survival rates for Groups I, II, III, and IV were 73.5% (25/34), 75% (3/4), 38.1% (8/21), and 70.0% (14/20), respectively. Survival rates were higher when PM was used: 70.8% (Groups II, IV) versus 60.0% (Groups I, III). Survival rates were significantly lower if diagnosed prenatally (PD+): 53.7% (Groups III, IV) versus 73.7% (Groups I, II) (P < 0.01). However, in PD+ groups, survival was significantly higher if PM was used (P < 0.05). PM significantly reduced length of hospital stay (35.5 vs. 52.0 days: P < 0.05). EC was found to be a predictor for survival while post-ductal AaDO(2) was not. In 17 cases with cardiac anomalies, PM did not affect survival. Our study suggests that use of PM for prenatally diagnosed CDH cases is associated with improved outcome, although the components of PM need to be tested in prospective trials to determine their true value.
journal_name
Pediatr Surg Intjournal_title
Pediatric surgery internationalauthors
Okawada M,Okazaki T,Yamataka A,Yanai T,Kato Y,Kobayashi H,Lane GJ,Miyano Tdoi
10.1007/s00383-006-1759-8subject
Has Abstractpub_date
2006-11-01 00:00:00pages
925-30issue
11eissn
0179-0358issn
1437-9813journal_volume
22pub_type
杂志文章abstract：PURPOSE:The Mac-2-binding protein glycosylation-modified isomer (M2BPGi) is a new marker for progression of hepatic fibrosis. We examined the relationship between serum M2BPGi levels and liver histological findings in patients with biliary atresia (BA) who were not transplant candidates. METHODS:Patients with BA who w...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4317-2
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:To compare the safety and efficacy between laparoscopic and open cyst excision with hepaticojejunostomy for children with choledochal cysts using meta-analysis. METHODS:Studies comparing the laparoscopic and the open choledochal cyst excision that met the inclusion criteria for data extraction were identifie...
journal_title：Pediatric surgery international
pub_type： 杂志文章,meta分析
doi：10.1007/s00383-015-3705-0
更新日期：2015-06-01 00:00:00
abstract：:A neonate with a constellation of unusual congenital deformities associated with pulmonary agenesis is reported. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050603
更新日期：1999-07-01 00:00:00
abstract：:An isolated bowel segment (IBS) is a viable loop of bowel that is completely free of its mesenteric attachments. In this study, omentoenteropexy (OEP) was performed in 5-cm-long IBS of rats in order to provide neovascularization. Thirty-two rats were divided into four groups. After OEP, mesenteric division of the IBSs...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF01076940
更新日期：1997-07-01 00:00:00
abstract：UNLABELLED:Anorectal malformation (ARM) is a group of significant birth defects with geographic variation in incidence, individual phenotypes and regional geographic subtypes occurring in approximately 1:5,000 live births. Anorectal atresia with gross terminal colonic distension in the presence of an absent anal canal ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00383-013-3346-0
更新日期：2013-12-01 00:00:00
abstract：:This report describes three children, age range 7 weeks to 5 months, who presented with obstructive jaundice secondary to gallstones. Previous Escherichia coli septicaemia and frusemide therapy were predisposing risk factors in two of the patients. All three were successfully treated with cholecystectomy and explorati...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：:A simple, quick, painless, and versatile dressing that fulfills most of the criteria of an ideal hypospadias dressing is described. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1206-7
更新日期：2004-05-01 00:00:00
abstract：:To determine the incidence of cystic fibrosis (CF) in neonates with intestinal obstruction (NIO) secondary to meconium ileus (MI), jejunoileal atresia (JA), meconium plug syndrome (MPS), volvulus (V), and meconium peritonitis (MP) and analyze the correlation of ultrasonographic (US) signs with CF in NIO with a prenata...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-002-0781-8
更新日期：2003-04-01 00:00:00
abstract：:Recent reports indicate that extracellular matrix and cytoskeleton plasmalemmal elements are altered in infantile hypertrophic pyloric stenosis (IHPS). Desmin is a cytoskeletal protein that is important for the organization and function of muscular fibers. It has been found to be increased in the smooth muscle in chro...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050745
更新日期：2000-01-01 00:00:00
abstract：:Accessory hepatic tissue, unlike accessory splenic and pancreatic tissue, is rare and has a limited and almost exclusively sub diaphragmatic distribution. Fewer than ten cases of intrathoracic ectopic liver have been reported so far in the literature. This paper reports a case that caused a diagnostic dilemma. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s003830000520
更新日期：2001-07-01 00:00:00
abstract：:Postoperative abdominal evisceration may lead to high morbidity and mortality. The purpose of the present study was to determine possible risk factors, morbidity and mortality associated with abdominal evisceration in children. A total of 3,591 children underwent abdominal exploration in our clinic between 1983 and 20...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-006-1722-8
更新日期：2006-08-01 00:00:00
abstract：:Non-operative management of gastroschisis also known as plastic closure (PC) has been described as an alternative to conventional primary operative closure (POC) or staged silo closure (SSC). The aim of this study was to compare these techniques in neonates with gastroschisis. A retrospective review of neonates with g...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2153-5
更新日期：2008-07-01 00:00:00
abstract：:Glicentin, the main component of enteroglucagon, has trophic effects on intestinal mucosa. It may also have an inhibitory effect on extraintestinal invasion of enteric bacteria. We have established an in vitro bioassay system for determining the effects of recombinant human glicentin on bacterial internalization by co...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1895-9
更新日期：2007-06-01 00:00:00
abstract：:Infected intra-abdominal cystic lymphangiomas are very rare. We report a case of a purulent mesenteric cyst, histologically a cystic lymphangioma, w which developed in a 1-year-old girl who presented with marked abdominal distension and high fever. Magnetic resonance imaging revealed that the huge cystic lesion occupi...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00174584
更新日期：1996-12-01 00:00:00
abstract：:Gastroschisis closure is performed either primarily or after staged reduction of the prolapsed bowel. A technique for surgical closure of the abdominal wall defect is described which allows for an almost scarless appearance of the abdominal surface with preservation of a midline umbilicus. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-008-2215-8
更新日期：2008-09-01 00:00:00
abstract：:We present three cases of abdominal and abdomino-thoracic extra-lobar pulmonary sequestrations detected by antenatal ultrasound (US) over a 12-month period. In addition, we briefly refer to a case previously described. A cystic mass was demonstrated in the left upper abdomen of the fetus in all four cases, with two ex...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/BF00183739
更新日期：1996-03-01 00:00:00
abstract：:Africa faces a triple burden of disease; HIV, tuberculosis and malaria. Despite this, its population is expected to double over the next 45 years. There is a dire shortage of medical specialists and many countries lack suitably qualified doctors to train medical specialists. Videoconferencing offers the opportunity to...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-2085-5
更新日期：2008-02-01 00:00:00
abstract：:Mucosa-associated lymphoid tissue (MALT) lymphomas comprise a group of indolent B-cell non-Hodgkin lymphomas (NHL), which are rare in pediatric age. The clinical presentation of MALT lymphomas varies according to the location of the lymphoma. We report on a case of MALT lymphoma involving the appendix in a 6-year-old ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-007-1957-z
更新日期：2008-04-01 00:00:00
abstract：:Anorectal injuries (ARI) are uncommon in children in civil practice. In developed countries the injuries are mainly due to sexual abuse and firearms. This report reviews the experience in tropical Africa. A retrospective study of children aged 12 years or less managed for ARI over 10 years was undertaken. There were s...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000347
更新日期：2000-01-01 00:00:00
abstract：:We present the results of a 6-year review of appendicitis. In the event of diagnostic doubt, a policy of active observation was instituted. This review endorses the validity of such a policy, indicating that it does not expose patients to increased morbidity. Data were collected prospectively over a 6-year period on 1...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830000483
更新日期：2001-03-01 00:00:00
abstract：:Our case report details the clinical course and management of a neonate with acute life-threatening respiratory distress presenting soon after birth. She needed intubation and ventilation. A pericardial cyst was diagnosed after a CT scan and 2D echo investigation. As a temporizing procedure the fluid was tapped and th...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-003-0970-0
更新日期：2003-11-01 00:00:00
abstract：:Magnetic resonance cholangiopancreaticography (MRCP) was used to visualize the biliary tract in two children, aged 7 weeks and 10 years, with a choledochal cyst. MRCP was successful in both cases and the findings were confirmed by intraoperative cholangiography. ...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s003830050667
更新日期：1999-01-01 00:00:00
abstract：:Rhizomelic chondrodysplasia punctata (RCP), a rare autosomal recessive disease characterized by a disorder of peroxisome metabolism, has been shown to affect multiple organ systems. A neonate presenting with a colonic perforation in the first few hours of life was subsequently diagnosed with RCP. A literature search r...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-005-1426-5
更新日期：2005-08-01 00:00:00
abstract：INTRODUCTION:We assessed the impact of intestinal transplantation on Japanese pediatric patients with intestinal failure with data from the Japanese intestinal transplant registry. METHODS:Standardized forms were sent to all known intestinal transplantation programs, requesting information on transplants performed bet...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-013-3392-7
更新日期：2013-10-01 00:00:00
abstract：:Children with chronic idiopathic constipation (CIC) often end up at the surgeon when medical treatments have failed. This opinion piece discusses a recently described pattern of CIC called 'Rapid transit constipation (RTC)' first identified in 2011 as part of surgical workup. RTC was identified using a nuclear medicin...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-019-04587-x
更新日期：2020-01-01 00:00:00
abstract：:Hypospadias surgery is one of the most difficult areas in pediatric urology and has been characterized by constant evolution. Some of the surgical techniques proposed in the past are now considered inadequate because of an unacceptable complication rate or poor functional and aesthetic results. The key for assessing a...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-004-1147-1
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:Currently, there are two well-established methods of bowel lengthening in patients with short bowel syndrome (SBS)-longitudinal intestinal lengthening and tailoring (LILT) and serial transverse enteroplasty (STEP) [1-4]. Both procedures may carry a high reported morbidity and mortality of 30.2% and 14.4%, re...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-020-04767-0
更新日期：2021-01-01 00:00:00
abstract：:Polyps in gastrointestinal tract are mostly benign and result from hamartomas or lymphoid hyperplasia of submucosa. They usually occur as isolated lesions in children and are referred to as juvenile polyps. Multiple polyps with inherited origin are called polyposis and can be seen as a part of the syndrome. The polyps...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-020-04621-3
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Preoperative factors have been correlated with pre-incision hypotension (PIH) in children undergoing surgery, suggesting that PIH can be predicted through preoperative screening. We studied blood pressure (BP) changes in the 12 min following the induction of anesthesia to study the incidence of post-inductio...
journal_title：Pediatric surgery international
pub_type： 杂志文章
doi：10.1007/s00383-018-4359-5
更新日期：2018-12-01 00:00:00
abstract：:Recent advances in culturing of intestinal stem cells and pluripotent stem cells have led to the development of intestinal organoids. These are self-organizing 3D structures, which recapitulate the characteristics and physiological features of in vivo intestinal epithelium. Intestinal organoids have allowed the develo...
journal_title：Pediatric surgery international
pub_type： 杂志文章,评审
doi：10.1007/s00383-019-04581-3
更新日期：2020-01-01 00:00:00
