Abstract:
OBJECTIVES:The aim of the study was to evaluate new bone formation under etched titanium (SLA) and modified-etched hydrophilic titanium (modSLA) domes placed on the calvarium of healthy, osteoporotic and osteoporotic treated with bisphosphonates rabbits. METHODS:Experimental osteoporosis was induced by ovariectomy (OV) and calcium-deficient diet in 24 New Zealand female rabbits. Twelve OV rabbits were treated with weekly dozes of alendronate (Fosamax(®)) (B) while 12 OV rabbits received no treatment (O). Another 12 rabbits were sham operated and used as healthy controls (C). At 6 weeks following OV, one modSLA and one SLA titanium dome were placed in the parietal bones of each rabbit. The animals were sacrificed at 30 and 120 days following the dome placement. Various histomorphometric measurements were performed in the most central of the undecalcified sections produced. RESULTS:After 30 days of healing, in the C group, the total bone (TB) area was 37.6% and 37.0% under the modSLA and SLA domes, respectively. In the O group, the TB was 35.7% and 24.8%. In the B group, TB was 37.0% and 32.1%, respectively. After 120 days of healing, in the C group TB was 40.1% and 36.4%, respectively. In the O group, TB was 29.6% and 27.9%, respectively. In the B group, TB was 49.7% and 42.5%, respectively. Hierarchical analysis of variance showed that the type of titanium dome significantly influenced new bone and the amount of new bone being in contact with inner surface of the dome (BIC) independently of the observation period and group (P<0.05). The administration of bisphosphonates influenced the BIC (P<0.05). CONCLUSION:The use of modSLA surface may promote bone healing and osseointegration in osteoporotic rabbits, whereas administration of bisphosphonates may compromise the osseointegration of the newly formed bone at the early healing period.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Mardas N,Schwarz F,Petrie A,Hakimi AR,Donos Ndoi
10.1111/j.1600-0501.2010.02094.xsubject
Has Abstractpub_date
2011-04-01 00:00:00pages
406-15issue
4eissn
0905-7161issn
1600-0501journal_volume
22pub_type
杂志文章abstract:OBJECTIVES:The objective of this study was to evaluate peri-implant soft tissue attachment and alveolar bone height on nanoporous TiO(2) thin film on commercial titanium dental implants compared with unmodified standard implants. MATERIAL AND METHODS:In six adult beagle dogs, the mandibular premolars P2-P4 were extrac...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01478.x
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVES:Published information regarding the use of rat jawbones for dental implant osseointegration research is limited and often inconsistent. This study assessed the suitability and feasibility of placing dental implants into the rat maxilla and to establish parameters to be used for dental implant research using ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12571
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:To compare clinical and radiographic outcomes between transcrestal sinus floor elevation (TSFE) and lateral sinus floor elevation (LSFE) approaches of simultaneous implant placement in atrophic maxilla. MATERIALS AND METHODS:Patients with a residual bone height (RBH) ≤6 mm were enrolled and randomly assigne...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13688
更新日期:2020-11-21 00:00:00
abstract:OBJECTIVES:The aim of this study was to histologically compare the dynamics of bone healing response between calcium sulphate (CaS) and deproteinized bovine bone mineral (DBBM) particles in guided bone regeneration utilizing an extracellular matrix membrane (ECM) as barrier. MATERIALS AND METHODS:Eighteen rabbits were...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12425
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:This in vitro study describes and characterizes a developed novel method to produce coatings on Ti. Hydrophobic coatings on substrates are needed in prosthetic dentistry to promote durable adhesion between luting resin cements and coated Ti surfaces. In implant dentistry the hydrophobic coatings on a Ti impl...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02504.x
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVES:This study aimed at evaluating the biological response of titanium implants coated with UV-irradiated 7-dehydrocholesterol (7-DHC) and vitamin E (VitE) in vivo and analyzing the effects of aging on their stability and bioactivity in vitro. MATERIAL AND METHODS:Titanium surfaces were coated with 7-DHC and Vi...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12815
更新日期:2017-04-01 00:00:00
abstract::This paper reports a 5-year life-table analysis on wide neck (WN) ITI implants placed in a private practice. In 212 patients, 263 implants were placed in the posterior region; 97% rehabilitated the molar area. Implants in the mandible and in the maxilla were 61.2% and 38.8%, respectively; the mean implant length was 9...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01271.x
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:To investigate the role of different levels of pH of artificial saliva under simulated oral environment on the corrosion behavior of commercially pure titanium (cp-Ti) and Ti-6Al-4V alloy. Special attention is given to understand the changes in corrosion kinetics and surface characterization of Ti by using e...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02265.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the influence of the configuration of the marginal aspect of implants placed immediately into extraction sockets on peri-implant hard tissue adaptation. MATERIAL AND METHODS:In 6 Labrador dogs, endodontic treatments of the mesial roots of 1 M1 were performed and the distal roots were removed. 2 P...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12262
更新日期:2014-10-01 00:00:00
abstract:AIM:This study sought to investigate dimensional changes to the alveolar bone following extraction and application of novel devices used for obturation of socket orifice (socket cap) and space maintenance in sockets with facial dehiscence (socket cage). MATERIAL AND METHODS:Six Macaca fascicularis had six teeth each r...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12521
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:The aim of the present systematic review was to analyze the survival and complication rates of zirconia-based and metal-ceramic implant-supported single crowns (SCs). MATERIALS AND METHODS:An electronic MEDLINE search complemented by manual searching was conducted to identify randomized controlled clinical ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13306
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:The aim of this investigation was to evaluate histologically, histometrically, and histomorphometrically the influence of plaque accumulation on the peri-implant hard tissues. MATERIAL AND METHODS:Twelve fully edentulous subjects were selected for this investigation. Four to five standard titanium screw imp...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0501.2003.00849.x
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVES:To investigate the effect of treated periodontitis on implant outcomes in partially edentulous individuals compared with periodontally healthy patients. MATERIAL AND METHODS:Longitudinal studies reporting on implant survival, success, incidence of peri-implantitis, bone loss and periodontal status, and on p...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/clr.12684
更新日期:2016-07-01 00:00:00
abstract::Ultra-sonic bone surgery (USBS) has been recently introduced as a novel osteotomic technique. This clinical study reports on the application of this new technique to perform ridge-split procedures. Over a period of 3.5 years, 57 patients underwent a split-crest procedure with the aim to place 230 implants, 78 in the m...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01206.x
更新日期:2006-12-01 00:00:00
abstract::The present study was designed to test perforated and non-perforated barriers for their ability to promote augmentation of bone tissue. More specifically, 1 totally occlusive barrier and 6 barriers with perforation sizes of about 10, 25, 50, 75, 100, and 300 microns and 1 group with no barriers placed (open test chamb...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090406.x
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVES:Primary implant stability is related to local bone density. After insertion of an implant, implant stability is subject to changes due to bone remodeling. In patients who have undergone radiotherapy in the head and neck region, implant stability is impaired because irradiation reduces bone vitality. The curr...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01457.x
更新日期:2008-02-01 00:00:00
abstract::Dental implant surfaces are important in determining the tissue/surface interaction. One of the first cells to adhere to the implant surface is the monocyte. This study examines the effect of surface roughness on monocyte adhesion and cytokine secretion. Monocyte adherence to titanium discs of 4 different degrees of s...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130111.x
更新日期:2002-02-01 00:00:00
abstract::The information concerning the molecular events taking place in onlay bone grafts are still incipient. The objective of the present study is to correlate the effects of perforation of resident bone bed on (1) the timing of onlay autogenous graft revascularization; (2) the maintenance of volume/density of the graft (as...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01485.x
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to radiologically and histologically evaluate the graft healing and volumetric changes after lateral augmentation with two different compositions of deproteinized bovine bone (DPBB) and autogenous bone (AB). MATERIAL AND METHODS:Thirteen patients with a mean age of 59.6 ± 12.1 years ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12143
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:To describe the early biofilm formation over whole dental implants with its micro- and macrostructure, using an in vitro multispecies biofilm model. MATERIAL AND METHODS:Six bacterial strains (Streptococcus oralis, Actinomyces naeslundii, Veillonella parvula, Fusobacterium nucleatum, Porphyromonas gingivali...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13409
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate hard and soft tissues around implants placed in posterior mandible 1 year after vertical ridge augmentation (VRA). MATERIALS AND METHODS:40 patients with vertical defects were enrolled and treated according to the study protocol. Patients were randomly divided into two ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13673
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Information of implant periapical lesion(IPL) is insufficient by now. The aim of this review is to analyze the possible causes of IPL and to find out the proper treatment protocol. MATERIAL AND METHODS:A systematic literature search was carried out (up to June 2012) using relevant search terms in PUBMED. And...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/clr.12232
更新日期:2014-09-01 00:00:00
abstract:AIM:The aim of this prospective study was to evaluate the outcome of computer-guided flapless placement and immediate loading of four conical screw-type implants in the interforaminal region. PATIENTS AND METHODS:From May to August 2003, 25 consecutive patients (m : f=16 : 9) with edentulous mandibles were included in...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01370.x
更新日期:2007-08-01 00:00:00
abstract:AIM:To investigate bone-to-implant bonding for some novel surface modifications with a hierarchic structure and to correlate the in vivo results with surface roughness parameters. MATERIALS AND METHODS:Newly developed implants surfaces were tested in rabbits and compared with the commercially available OsseoSpeed™ (OS...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02233.x
更新日期:2012-08-01 00:00:00
abstract::Parkinson's disease (PD) often affects the oro-pharyngeal musculature, leading to problems with speaking, chewing and swallowing. The inevitable reduction in food and fluid intake contributes to the further deterioration of neurological symptoms. Parkinson's disease patients have great difficulties in adjusting to the...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2000.011006566.x
更新日期:2000-12-01 00:00:00
abstract::The aim of this study was to evaluate the soft tissue conditions at osseo-integrated oral implants in relation to the width of masticatory mucosa. Thirty-nine patients who had received a full-arch fixed bridge reconstruction > or = 10 years ago or a partial reconstruction > or = 5 years ago on a total of 171 implants ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1994.050101.x
更新日期:1994-03-01 00:00:00
abstract:OBJECTIVES:The aim of this investigation was to evaluate the potential effects of the systemically delivered combination of calcium supplementation and cholecalciferol and of the locally applied biphasic calcium alloplast on the surgically produced alveolar sockets at the early healing stage in a dog model. MATERIALS ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02284.x
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:Although implants with a roughened surface are widely used today, little is known about the long-term effect of a roughened surface compared with the conventional machined surface on clinical and radiographic parameters. The purpose of this study is to investigate the long-term differences between moderately...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2009.01768.x
更新日期:2009-11-01 00:00:00
abstract::The prosthodontic section of the 1997 ITI Consensus Conference in Vitznau, Switzerland, examined a broad spectrum of issues related to the prosthodontic phase of dental implant therapy. Topics included diagnosis and treatment planning, considerations for the use of ITI prosthodontic components, management of the parti...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章,评审
doi:10.1034/j.1600-0501.2000.011s1101.x
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Cement-retained fixed implant-supported restorations involve the risk of excess cement, which can associate peri-implantitis. In connection with routine therapy using a methacrylate cement (Premier Implant Cement, Premier(®) Dental Products Company, Plymouth Meeting, PA, USA) to retain fixed implant-supporte...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12173
更新日期:2014-07-01 00:00:00