当前位置： SCI文献检索 > CLINICAL ORAL IMPLANTS RESEARCH期刊下所有文献 > Evaluation of the first maxillary molar post-extraction socket as a model for dental implant osseointegration research.

Evaluation of the first maxillary molar post-extraction socket as a model for dental implant osseointegration research.

Abstract：

OBJECTIVES:Published information regarding the use of rat jawbones for dental implant osseointegration research is limited and often inconsistent. This study assessed the suitability and feasibility of placing dental implants into the rat maxilla and to establish parameters to be used for dental implant research using this model. MATERIALS AND METHODS:Forty-two customized titanium implants (2 × 3 mm) were placed bilaterally in the maxillary first molar area of 21 Sprague-Dawley rats. Every animal received two implants. The animals were subsequently sacrificed at days 3, 7, 14, 28 and 56 post-surgery. Resin-embedded sections of the implant and surrounding maxilla were prepared for histological and histomorphometric analyses. RESULTS:The mesial root of the first molar in the rat maxilla was the optimal site to place the implant. Although the most apical 2-3 threads of the implant penetrated into the sinus cavity, 2 mm of the remaining implant was embedded in the bone. New bone formation at day 7 around the implant increased further at day 14, as measured by the percentage of bone-to-implant contact (%BIC) and new bone area (%BA) in the implant thread chambers (55.1 ± 8.9% and 63.7 ± 7.7%, respectively). There was a further significant increase between day 14 and 28 (P < 0.05), however, no significant differences were found between day 28 and 56 in either %BIC or %BA. CONCLUSIONS:The mesial root socket of the first molar in the rat maxilla is a useful model for dental implant research. Osseointegration following implant placement as measured by BIC plateaued after 28 days. The recommended implant dimensions are 1.5 mm in diameter and 2 mm in length.

journal_name

Clin Oral Implants Res

journal_title

Clinical oral implants research

authors

Du Z,Lee RS,Hamlet S,Doan N,Ivanovski S,Xiao Y

doi

10.1111/clr.12571

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

1469-1478

issue

12

eissn

0905-7161

issn

1600-0501

journal_volume

27

pub_type

杂志文章

相关文献

CLINICAL ORAL IMPLANTS RESEARCH文献大全
  • Guided bone regeneration with particulate vs. block xenogenic bone substitutes: a pilot cone beam computed tomographic investigation.

    abstract：AIM:To test whether an equine bone substitute block used for guided bone regeneration (GBR) of peri-implant defects differs from bovine block or particulate bone substitutes regarding the hard and soft tissue contours of the augmented ridge. MATERIAL & METHODS:Two semi-saddle bone defects were prepared in each side of...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.13011

    authors： Benic GI,Thoma DS,Jung RE,Sanz-Martin I,Unger S,Cantalapiedra A,Hämmerle CHF

    更新日期：2017-11-01 00:00:00

  • Mandibular single-implant overdentures: a review with surgical and prosthodontic perspectives of a novel approach.

    abstract：OBJECTIVES:To review the literature on mandibular single-implant overdentures (opposing complete maxillary dentures), and present surgical and prosthodontic perspectives of a novel approach for this treatment option. MATERIAL AND METHODS:An electronic search through the databases of Pubmed, Embase and Medline using th...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章,评审

    doi：10.1111/j.1600-0501.2008.01666.x

    authors： Alsabeeha N,Payne AG,De Silva RK,Swain MV

    更新日期：2009-04-01 00:00:00

  • On the relationship between gingival biotypes and gingival thickness in young Caucasians.

    abstract：OBJECTIVES:To evaluate a possible relationship between gingival biotypes and gingival thickness, papilla height and gingival width. MATERIAL AND METHODS:Thirty-six adult subjects were stratified by their gingival biotype (GB), as defined by transparency of a periodontal probe through the buccal gingival margin, into "...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.12356

    authors： Fischer KR,Richter T,Kebschull M,Petersen N,Fickl S

    更新日期：2015-08-01 00:00:00

  • Soft tissue around three different implant types after 1.5 years of functional loading without oral hygiene: a preliminary study in baboons.

    abstract：:The purpose of this study was to determine the peri-implant soft tissue dimension (PSD) and peri-implant bone level (BL) of dental implants with different designs and surface modifications after functional loading without oral hygiene. Three types of dental implants were placed in the posterior jaws of adult baboons, ...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0501.2005.01217.x

    authors： Watzak G,Zechner W,Tangl S,Vasak C,Donath K,Watzek G

    更新日期：2006-04-01 00:00:00

  • Two-year clinical outcomes following non-surgical mechanical therapy of peri-implantitis with adjunctive diode laser application.

    abstract：BACKGROUND:Non-surgical mechanical therapy of peri-implantitis (PI) with/without adjunctive measures yields limited clinical improvements. AIM:To evaluate the clinical outcomes following non-surgical mechanical therapy of PI with adjunctive application of a diode laser after an observation period ≥2 years. MATERIAL A...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.12689

    authors： Mettraux GR,Sculean A,Bürgin WB,Salvi GE

    更新日期：2016-07-01 00:00:00

  • A histomorphometric evaluation of screw-shaped implants each prepared with two surface roughnesses.

    abstract：:Four different surface modifications were designed. Forty screw-shaped implants were divided into 4 groups, 10 screws in each. Every screw was prepared with 2 different surface topographies. The surface topography was measured with a confocal laser scanning profilometer and the surface roughness was characterized usin...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0501.1998.090102.x

    authors： Wennerberg A,Hallgren C,Johansson C,Danelli S

    更新日期：1998-02-01 00:00:00

  • Posterior alveolar ridge resorption in bar-retained mandibular overdentures: 10-year results of a prospective clinical trial.

    abstract：OBJECTIVES:Data on posterior alveolar ridge resorption (PARR) in patients with two implant supported mandibular overdentures is very heterogeneous. The aim of this prospective study was to observe the PARR after ten years for a study population treated with a titanium bar retained overdenture on two IMZ-implants. MATE...

    journal_title：Clinical oral implants research

    pub_type： 临床试验,杂志文章

    doi：10.1111/clr.12393

    authors： Raedel M,Lazarek-Scholz K,Marré B,Boening KW,Walter MH

    更新日期：2015-12-01 00:00:00

  • Sinus floor elevation or referral for further diagnosis and therapy: A comparison of maxillary sinus assessment by ENT specialists and dentists using cone beam computed tomography.

    abstract：OBJECTIVES:To compare ear, nose, and throat (ENT) specialists and dentists assessing health or pathology of maxillary sinuses using cone beam computed tomography (CBCT). MATERIAL AND METHODS:Two ENT specialists and two oral surgeons assessed 100 CBCT datasets of healthy patients referred for dental implant placement i...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.13582

    authors： Janner SFM,Dubach P,Suter VGA,Caversaccio MD,Buser D,Bornstein MM

    更新日期：2020-05-01 00:00:00

  • Rotating titanium brush for plaque removal from rough titanium surfaces--an in vitro study.

    abstract：OBJECTIVES:The purpose of this study was the evaluation of the effectiveness of plaque removing of a new rotating brush made of titanium in comparison with the cleaning procedure with steel curettes. MATERIALS AND METHODS:Plaque was collected by six volunteers for 48 h. A total of 60 samples were randomly designated t...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.12147

    authors： John G,Becker J,Schwarz F

    更新日期：2014-07-01 00:00:00

  • Characterization of novel silane coatings on titanium implant surfaces.

    abstract：OBJECTIVES:This in vitro study describes and characterizes a developed novel method to produce coatings on Ti. Hydrophobic coatings on substrates are needed in prosthetic dentistry to promote durable adhesion between luting resin cements and coated Ti surfaces. In implant dentistry the hydrophobic coatings on a Ti impl...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0501.2012.02504.x

    authors： Matinlinna JP,Tsoi JK,de Vries J,Busscher HJ

    更新日期：2013-06-01 00:00:00

  • Computer-guided flapless placement and immediate loading of four conical screw-type implants in the edentulous mandible.

    abstract：AIM:The aim of this prospective study was to evaluate the outcome of computer-guided flapless placement and immediate loading of four conical screw-type implants in the interforaminal region. PATIENTS AND METHODS:From May to August 2003, 25 consecutive patients (m : f=16 : 9) with edentulous mandibles were included in...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0501.2007.01370.x

    authors： Wittwer G,Adeyemo WL,Wagner A,Enislidis G

    更新日期：2007-08-01 00:00:00

  • A new index for rating aesthetics of implant-supported single crowns and adjacent soft tissues--the Implant Crown Aesthetic Index.

    abstract：OBJECTIVES:The important item of aesthetics is rarely included in evaluation studies. The aim of this study was to develop and validate an index for rating aesthetics of implant-supported single crowns and adjacent soft tissues. MATERIAL AND METHODS:Nine items were selected, which have an influence on the aesthetic re...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0501.2005.01128.x

    authors： Meijer HJ,Stellingsma K,Meijndert L,Raghoebar GM

    更新日期：2005-12-01 00:00:00

  • Implant-tissue interfaces following treatment of peri-implantitis using guided tissue regeneration: a light and electron microscopic study.

    abstract：:This study details the structural and ultrastructural features of the interfaces between titanium implants and their surrounding tissues. The material stemmed from an experiment in dogs in which guided tissue regeneration with Gore-Tex membranes was used to treat peri-implant, ligature-induced tissue breakdown around ...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0501.1994.050201.x

    authors： Schüpbach P,Hürzeler M,Grunder U

    更新日期：1994-06-01 00:00:00

  • Immediate transmucosal implants using the principle of guided tissue regeneration. I. Rationale, clinical procedures and 30-month results.

    abstract：:The installation of implants directly into extraction sockets offers considerable advantages over other treatment modalities for both practitioners and patients. Usually, immediate implants are placed and subsequently covered by mucosa allowing a submerged healing mode. This report presents the rationale, clinical pro...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0501.1994.050306.x

    authors： Lang NP,Brägger U,Hämmerle CH,Sutter F

    更新日期：1994-09-01 00:00:00

  • Cement-associated peri-implantitis: a retrospective clinical observational study of fixed implant-supported restorations using a methacrylate cement.

    abstract：BACKGROUND:Cement-retained fixed implant-supported restorations involve the risk of excess cement, which can associate peri-implantitis. In connection with routine therapy using a methacrylate cement (Premier Implant Cement, Premier(®) Dental Products Company, Plymouth Meeting, PA, USA) to retain fixed implant-supporte...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.12173

    authors： Korsch M,Obst U,Walther W

    更新日期：2014-07-01 00:00:00

  • Comparative evaluation of casting retention using the ITI solid abutment with six cements.

    abstract：OBJECTIVE:The purpose of this study was to test the retention of metal copings fabricated to fit on the one-groove, one flat-sided solid titanium abutment using six different cements. MATERIALS AND METHODS:Ten hollow screw 3.8 mm ITI implants were mounted in acrylic resin blocks. A solid titanium abutment was placed o...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0501.2002.130401.x

    authors： Mansour A,Ercoli C,Graser G,Tallents R,Moss M

    更新日期：2002-08-01 00:00:00

  • Evaluation of peri-implant tissues condition after 10-15 years of loading in treated chronic periodontitis patients attending a private practice setting: A retrospective study.

    abstract：OBJECTIVES:To retrospectively evaluate the conditions of the peri-implant tissues in treated patients with chronic periodontitis (CP) and in patients without chronic periodontitis (noCP). MATERIALS AND METHODS:A chart review was used to evaluate 267 implants, 134 placed in 42 CP treated patients and 133 placed in 46 n...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.13712

    authors： Guarnieri R,Di Nardo D,Di Giorgio G,Miccoli G,Testarelli L

    更新日期：2021-01-16 00:00:00

  • Prospective randomized controlled clinical study comparing two types of two-piece dental implants supporting fixed reconstructions-Results at 5 years of loading.

    abstract：OBJECTIVES:Compare clinical outcomes of two types of dental implants with non-matching implant-abutment junctions loaded with fixed implant-borne reconstructions at 5 years of loading. MATERIALS AND METHODS:In 64 patients, one of two implant systems (S1, S2) was randomly used to support fixed dental prostheses (FDP). ...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/clr.13526

    authors： Ioannidis A,Heierle L,Hämmerle CHF,Hüsler J,Jung RE,Thoma DS

    更新日期：2019-11-01 00:00:00

  • Tissue integration of non-submerged implants. 1-year results of a prospective study with 100 ITI hollow-cylinder and hollow-screw implants.

    abstract：:It has been postulated that the wound healing in a closed submerged location is one of the prerequisites for osseointegration of dental implants. The purpose of the present study was to evaluate the tissue integration of intentionally non-submerged titanium implants inserted by a one-stage surgical procedure. 100 ITI ...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0501.1990.010105.x

    authors： Buser D,Weber HP,Lang NP

    更新日期：1990-12-01 00:00:00

  • The current use of patient-centered/reported outcomes in implant dentistry: a systematic review.

    abstract：AIM:To provide an update on the use of Patient-Reported Outcome Measures (PROMs) in the field of implant dentistry (1); to compare PROMs for prostheses supported by one or more implants to alternative treatment options or a healthy dentition (2). MATERIALS AND METHODS:The dental literature was searched on PubMed until...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章,评审

    doi：10.1111/clr.12634

    authors： De Bruyn H,Raes S,Matthys C,Cosyn J

    更新日期：2015-09-01 00:00:00

  • The comparative evaluation of transcrestal and lateral sinus floor elevation in sites with residual bone height ≤6 mm: A two-year prospective randomized study.

    abstract：OBJECTIVES:To compare clinical and radiographic outcomes between transcrestal sinus floor elevation (TSFE) and lateral sinus floor elevation (LSFE) approaches of simultaneous implant placement in atrophic maxilla. MATERIALS AND METHODS:Patients with a residual bone height (RBH) ≤6 mm were enrolled and randomly assigne...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/clr.13688

    authors： Zhou Y,Shi Y,Si M,Wu M,Xie Z

    更新日期：2020-11-21 00:00:00

  • Esthetic, clinical and patient-centered outcomes of immediately placed implants (Type 1) and early placed implants (Type 2): preliminary 3-month results of an ongoing randomized controlled clinical trial.

    abstract：AIM:The objective of the study was to compare (i) esthetic, (ii) clinical and (iii) patient-centered outcomes following immediate (Type 1) and early implant placement (Type 2). MATERIAL AND METHODS:Thirty-eight subjects needing a single extraction (premolar to premolar) were randomly allocated to Type 1 or Type 2 impl...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/clr.12577

    authors： Huynh-Ba G,Meister DJ,Hoders AB,Mealey BL,Mills MP,Oates TW,Cochran DL,Prihoda TJ,McMahan CA

    更新日期：2016-02-01 00:00:00

  • Performance and outcome of zirconia dental implants in clinical studies: A meta-analysis.

    abstract：OBJECTIVES:To evaluate implant survival, peri-implant marginal bone loss, technical, and biological complications as well as aesthetic outcomes of zirconia implants in clinical studies. MATERIAL AND METHODS:Electronic (Medline, Embase) and hand searches were performed to identify clinical studies published between Jan...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章,meta分析

    doi：10.1111/clr.13352

    authors： Roehling S,Schlegel KA,Woelfler H,Gahlert M

    更新日期：2018-10-01 00:00:00

  • Influence of initial implant mobility on the integration of titanium implants. An experimental study in rabbits.

    abstract：:In the present study, the influence of initial instability on the healing of titanium implants was studied in 9 lop-eared rabbits. Titanium implants (Brånemark System) were inserted in the tibiae, a location with cortical bone only, in such a way that they were either stable (control), rotation-mobile, or totally mobi...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：

    authors： Ivanoff CJ,Sennerby L,Lekholm U

    更新日期：1996-06-01 00:00:00

  • Enhanced osteoblast response to hydrophilic strontium and/or phosphate ions-incorporated titanium oxide surfaces.

    abstract：OBJECTIVE:This study investigated the surface characteristics and in vitro biocompatibility of titanium (Ti) surfaces incorporated with strontium ions (Sr) and/or phosphate ions (P) produced by hydrothermal treatment for future applications as endosseous implant surfaces. MATERIAL AND METHODS:Sr and/or P-incorporated ...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0501.2009.01863.x

    authors： Park JW,Kim YJ,Jang JH

    更新日期：2010-04-01 00:00:00

  • Immediately restored one-piece single-tooth implants with reduced diameter: one-year results of a multi-center study.

    abstract：OBJECTIVES:The aim of the present multi-center study was to evaluate the treatment outcome of immediately restored one-piece single-tooth implants with a diameter of 3 mm after 1 year. MATERIAL AND METHODS:A total of 57 one-piece implants (NobelDirect 3.0) were inserted in 47 patients (26 females, 21 males) with a mea...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章,多中心研究

    doi：10.1111/j.1600-0501.2011.02174.x

    authors： Zembić A,Johannesen LH,Schou S,Malo P,Reichert T,Farella M,Hämmerle CH

    更新日期：2012-01-01 00:00:00

  • Temperature increases during surface decontamination of titanium implants using CO2 laser.

    abstract：:The purpose of the present in vitro investigation was to measure temperature changes at the implant surface when using pulsed CO2 laser in a simulated implant surface decontamination protocol. Six threaded titanium implants were placed in a fresh resected pig mandible. A 4 x 4 mm defect was created buccally to each im...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0501.1999.100107.x

    authors： Mouhyi J,Sennerby L,Nammour S,Guillaume P,Van Reck J

    更新日期：1999-02-01 00:00:00

  • Ridge preservation following tooth extraction using a polylactide and polyglycolide sponge as space filler: a clinical and histological study in humans.

    abstract：BACKGROUND:The placement of different graft materials and/or the use of occlusive membranes to cover the extraction socket entrance are techniques aimed at preserving/reducing alveolar ridge resorption. The use of grafting materials in fresh extraction sockets has, however, been questioned because particles of the graf...

    journal_title：Clinical oral implants research

    pub_type： 临床试验,杂志文章

    doi：10.1034/j.1600-0501.2003.00970.x

    authors： Serino G,Biancu S,Iezzi G,Piattelli A

    更新日期：2003-10-01 00:00:00

  • Split-crest and immediate implant placement with ultra-sonic bone surgery: a 3-year life-table analysis with 230 treated sites.

    abstract：:Ultra-sonic bone surgery (USBS) has been recently introduced as a novel osteotomic technique. This clinical study reports on the application of this new technique to perform ridge-split procedures. Over a period of 3.5 years, 57 patients underwent a split-crest procedure with the aim to place 230 implants, 78 in the m...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1111/j.1600-0501.2006.01206.x

    authors： Blus C,Szmukler-Moncler S

    更新日期：2006-12-01 00:00:00

  • The influence of the masticatory mucosa on the peri-implant soft tissue condition.

    abstract：:The aim of this study was to evaluate the soft tissue conditions at osseo-integrated oral implants in relation to the width of masticatory mucosa. Thirty-nine patients who had received a full-arch fixed bridge reconstruction > or = 10 years ago or a partial reconstruction > or = 5 years ago on a total of 171 implants ...

    journal_title：Clinical oral implants research

    pub_type： 杂志文章

    doi：10.1034/j.1600-0501.1994.050101.x

    authors： Wennström JL,Bengazi F,Lekholm U

    更新日期：1994-03-01 00:00:00