Abstract:
:Dental implant surfaces are important in determining the tissue/surface interaction. One of the first cells to adhere to the implant surface is the monocyte. This study examines the effect of surface roughness on monocyte adhesion and cytokine secretion. Monocyte adherence to titanium discs of 4 different degrees of surface roughness and plastic surfaces was assayed. Blood mononuclear cells were incubated for 1.5 h in 16 mm culture wells into which titanium discs had been placed. Non-adherent cells were washed off and the numbers of remaining adherent monocyte determined by DNA quantification. TNF-alpha and PGE2 secretion in media from overnight cultures of attached monocytes stimulated with lipopolysaccharide (LPS) was quantified using ELISA and RIA, respectively. Monocyte adherence to rough titanium surfaces was greater than to turned titanium surfaces, while the lowest adherence was to the plastic surface. No significant differences in adherence to 250, 75 or 25 microm blasted surfaces could be detected. The number of adherent monocytes increased with time, with maximum adhesion after 2 h of incubation. Incubation of monocytes adherent to titanium surfaces resulted in a decrease of less than 30% in their numbers over 7 days, whereas cells attached to plastic surfaces decreased to non-detectable numbers after 48 h. Porphyromonas gingivalis LPS stimulation upregulated TNF-alpha and PGE2 secretion into the media. The LPS-induced TNF-alpha and PGE2 secretion was independent of the titanium surface roughness, however the lowest amounts of TNF-alpha and PGE2 were secreted from cells attached to plastic surfaces. The results of this study indicate that the number of monocytes attached to blasted titanium surfaces is significantly greater than to machined titanium surfaces. PGE2 and TNF-alpha secretion is less influenced by titanium surface roughness.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Soskolne WA,Cohen S,Sennerby L,Wennerberg A,Shapira Ldoi
10.1034/j.1600-0501.2002.130111.xsubject
Has Abstractpub_date
2002-02-01 00:00:00pages
86-93issue
1eissn
0905-7161issn
1600-0501journal_volume
13pub_type
杂志文章abstract::The aim of the study was to evaluate the early colonization of non-submerged implants over a 6-month period in partially edentulous patients treated for advanced aggressive periodontal disease. In 22 patients treated for advanced aggressive periodontitis and in a supportive maintenance program for a period between 12 ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01175.x
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:The placement of different graft materials and/or the use of occlusive membranes to cover the extraction socket entrance are techniques aimed at preserving/reducing alveolar ridge resorption. The use of grafting materials in fresh extraction sockets has, however, been questioned because particles of the graf...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0501.2003.00970.x
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to radiologically and histologically evaluate the graft healing and volumetric changes after lateral augmentation with two different compositions of deproteinized bovine bone (DPBB) and autogenous bone (AB). MATERIAL AND METHODS:Thirteen patients with a mean age of 59.6 ± 12.1 years ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12143
更新日期:2014-03-01 00:00:00
abstract::The present paper describes the clinical and radiographic healing results of 27 implants followed from 1 to 3 years after functional implant loading. Prior to implant placement, alveolar ridges with insufficient bone volume were augmented using autogenous bone grafts and a micro titanium mesh for graft stabilization. ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090208.x
更新日期:1998-04-01 00:00:00
abstract::Microbial plaque accumulation on titanium dental implant surfaces can result in an inflammatory condition of the surrounding tissues. Cleaning of such a contaminated surface, in vivo, by means of a solution of amino-alcohol, following surgical exposure, has been proposed. However, the tissue healing following treatmen...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1999.100303.x
更新日期:1999-06-01 00:00:00
abstract::The placement of implants immediately after tooth extraction has become a relatively common event. This approach has gained popularity because it reduces the time between tooth extraction and placement of the final prosthetic restoration. One problem that remains unresolved with this procedure, however, is that there ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130611.x
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Low-temperature synthesized calcium phosphates are produced by mixing calcium phosphate powders in an aqueous solution resulting in a precipitated phase. These compounds can be formulated in several forms (e.g. injectable cements and implantable blocks), and are commonly used as bone substitutes and drug del...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01864.x
更新日期:2010-06-01 00:00:00
abstract::Non-submerged ITI Bonefit implants (ITI Dental Implant System) were inserted in edentulous lower jaws of 46 patients. The patients were provided with either a fixed prosthesis or an overdenture, and has been followed during a 2-year-period. At the 1-year examination, the suprastructures were removed permitting test of...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070406.x
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:The aim of this systematic review was to investigate the influence of bone mineral density on the primary stability of dental implants. MATERIAL AND METHODS:A search of health science databases (Cochrane Library, MEDLINE-PubMed, ISI Web of Knowledge, EMBASE, LILACS) and grey literature was performed, includi...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2011.02228.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effect of the topical application of melatonin compared with collagenized porcine bone grafts to accelerate bone formation 2 months after their insertion in tibiae rabbits. MATERIAL AND METHODS:Twenty New Zealand rabbits weighing 3,900-4,500 g were used. Twenty colla...
journal_title:Clinical oral implants research
pub_type: 杂志文章,收录出版
doi:10.1111/clr.12364
更新日期:2015-04-01 00:00:00
abstract::A clinical and radiographical study was performed to evaluate the treatment outcome of single tooth replacements with artificial crowns retained to implants installed according to a 1-stage surgical procedure and immediate loading (Experimental Group = EG) in comparison to the original 2-stage concept (Control Group =...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0501.2000.011001026.x
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVES:To compare clinical and radiographic outcomes between transcrestal sinus floor elevation (TSFE) and lateral sinus floor elevation (LSFE) approaches of simultaneous implant placement in atrophic maxilla. MATERIALS AND METHODS:Patients with a residual bone height (RBH) ≤6 mm were enrolled and randomly assigne...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13688
更新日期:2020-11-21 00:00:00
abstract:OBJECTIVES:To present the characteristics and level of evidence (LOE) of clinical studies published in leading oral implantology journals during 2008-2018 and to explore whether the LOE of a study is associated with its scientific and social impact. MATERIALS AND METHODS:Clinical studies with direct relevance to the e...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13641
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of strontium-oxide layer on new bone formation and osseointegration of sandblasted large-grit double-acid-etched (SLA) implant. MATERIAL AND METHODS:Strontium-oxide layer on the SLA surface was produced by hydrothermal treatment using a Sr-containing solution. The surface topographies...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12897
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To assess the influence of a collagen membrane placed subjacent to a pristine sinus mucosa on the healing outcome of a sinus floor elevation procedure. MATERIALS AND METHODS:Eight Pelibuey sheep (Cubano rojo) underwent sinus floor elevation on both sides of the maxilla. At a randomly selected side (test), a ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12762
更新日期:2016-11-01 00:00:00
abstract::The prosthodontic section of the 1997 ITI Consensus Conference in Vitznau, Switzerland, examined a broad spectrum of issues related to the prosthodontic phase of dental implant therapy. Topics included diagnosis and treatment planning, considerations for the use of ITI prosthodontic components, management of the parti...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章,评审
doi:10.1034/j.1600-0501.2000.011s1101.x
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:There is limited knowledge regarding the strength of zirconia abutments with internal and external implant abutment connections and zirconia abutments supported by a titanium resin base (Variobase, Straumann) for narrow diameter implants. OBJECTIVES:To compare the fracture strength of narrow diameter abutme...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13139
更新日期:2018-04-01 00:00:00
abstract:AIM:The aim of this biomechanical study was to assess the influence of self-tapping blades in terms of primary implant stability between implants with self-tapping blades and implants without self-tapping blades using five different analytic methods, especially in medium-density bone. MATERIALS AND METHODS:Two differe...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02089.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the preference of a patients' population, according to the index of willingness to pay (WTP), against two treatments to restore a single-tooth gap: the implant-supported crown (ISC) and the 3-unit fixed partial denture prosthesis (FPDP) on natural teeth. MATERIALS ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12264
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the outcomes of the installation of two implant-supported overdentures until such treatment is complete. Although this treatment is well established in the literature, there are no studies comparing what happens to muscles and the quality of life (QoL) of patients dur...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12980
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:A prospective double-blind randomised controlled trial was conducted to test the effect of prophylactic antibiotics on post-operative morbidity and osseointegration of dental implants. MATERIALS AND METHODS:Fifty-five subjects scheduled for implant surgery were enrolled. The patients were randomly assigned ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.12124
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:The aim of this prospective study was to evaluate the 5-year performance and success rate of titanium screw-type implants with the titanium plasma spray (TPS) or the sand-blasted, large grit, acid-etched (SLA) surface inserted in a two-stage sinus floor elevation (SFE) procedure in the posterior maxilla. MA...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01573.x
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:This study investigated the surface characteristics and in vitro biocompatibility of titanium (Ti) surfaces incorporated with strontium ions (Sr) and/or phosphate ions (P) produced by hydrothermal treatment for future applications as endosseous implant surfaces. MATERIAL AND METHODS:Sr and/or P-incorporated ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01863.x
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:To review systematically whether supportive implant treatment during a follow-up of at least 10 years after functional loading is effective in prevention of biological complications and fixture loss. METHODS:A MEDLINE search was conducted for the period of 1965 to April 2006 of longitudinal clinical studies ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2007.01447.x
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:The aim of this clinical study was to evaluate long-term outcomes of implant therapy in a cohort of immunosuppressed renal transplant patients compared with a matched control group. MATERIAL AND METHODS:Pharmacologically immunosuppressed renal transplant patients received dental implant treatment between 20...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13437
更新日期:2019-06-01 00:00:00
abstract:AIM:To test whether an equine bone substitute block used for guided bone regeneration (GBR) of peri-implant defects differs from bovine block or particulate bone substitutes regarding the hard and soft tissue contours of the augmented ridge. MATERIAL & METHODS:Two semi-saddle bone defects were prepared in each side of...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13011
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Although implants with a roughened surface are widely used today, little is known about the long-term effect of a roughened surface compared with the conventional machined surface on clinical and radiographic parameters. The purpose of this study is to investigate the long-term differences between moderately...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2009.01768.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to histologically compare the dynamics of bone healing response between calcium sulphate (CaS) and deproteinized bovine bone mineral (DBBM) particles in guided bone regeneration utilizing an extracellular matrix membrane (ECM) as barrier. MATERIALS AND METHODS:Eighteen rabbits were...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12425
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:Interforaminal implant surgery requires anatomical knowledge of the area and adequate information on the location of the various landmarks of significance such as the mental foramen, the anterior loop of the inferior alveolar nerve and the mandibular incisive canal. Cone beam computed tomography (CBCT) is a ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02261.x
更新日期:2012-09-01 00:00:00
abstract::Currently, 3 treatment options are available for patients with denture complaints and an edentulous mandible with a height of at least 15 mm: meticulous construction of a new set of dentures (CD), construction of a new set of dentures following preprosthetic surgery to enlarge the denture-bearing area (PPS), and const...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0501.2000.011003195.x
更新日期:2000-06-01 00:00:00