Abstract:
OBJECTIVES:The aim of this investigation was to evaluate the potential effects of the systemically delivered combination of calcium supplementation and cholecalciferol and of the locally applied biphasic calcium alloplast on the surgically produced alveolar sockets at the early healing stage in a dog model. MATERIALS AND METHODS:The mandibular pre-molars of nine Beagle dogs were extracted first. Three months later, four standardized sockets with a 4 mm in diameter and 6 mm deep cylinder were created bilaterally at healed extraction sites. The sockets on one side were grafted with biphasic calcium phosphate alloplast, whereas the defects on the other side were left un-grafted. The dogs were then randomly divided into two groups; five dogs received oral calcium and cholecalciferol combination (Vit.D/Ca) and were assigned to the test group (Vit.D/Ca Group). The other four dogs without Vit.D/Ca supplement were distributed to the control group (Non-Vit.D/Ca Group). The bone density (Density) and the implant stability quotient (ISQ) at prepared sites were measured 4 weeks later. The drawn bone cores were examined by a histomorphometric analysis for measurement of new bone formation (NBF). The amount of vertical ridge resorption (VRR) was evaluated. RESULTS:The Vit.D/Ca-treated subjects revealed significantly more NBF (P < 0.05), higher bone density (P < 0.05) and significantly less vertical ridge reduction (P < 0.05) in the healing sockets than those without Vit.D/Ca treatment. The non-grafted sockets demonstrated significantly more NBF (P < 0.05), higher bone density (P < 0.05), better ISQ value (P < 0.05) and more vertical ridge reduction (P < 0.05) than those in the grafted sockets. There was no significant difference between the serum data determined before and 4 weeks after experiment in Vit.D/Ca Group or Non-Vit.D/Ca Group. However, the changed value (post-op vs. pre-op) between the two groups was significant in the serum level of phosphate and parathyroid hormone (P = 0.05). CONCLUSION:The results of the present study indicated that the examined calcium phosphate alloplast may perform a function in alveolar ridge preservation while reducing the potential of NBF potential in the healing extraction socket. Also, the combination of calcium supplementation and cholecalciferol may have systemic effects on accelerating bone regeneration.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Hong HH,Chou TA,Yang JC,Chang CJdoi
10.1111/j.1600-0501.2011.02284.xsubject
Has Abstractpub_date
2012-10-01 00:00:00pages
1187-92issue
10eissn
0905-7161issn
1600-0501journal_volume
23pub_type
杂志文章abstract:OBJECTIVES:The aim of the study was to evaluate new bone formation under etched titanium (SLA) and modified-etched hydrophilic titanium (modSLA) domes placed on the calvarium of healthy, osteoporotic and osteoporotic treated with bisphosphonates rabbits. METHODS:Experimental osteoporosis was induced by ovariectomy (OV...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02094.x
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVES:To assess the impact of collagen membrane application on bone formation surrounding implants placed simultaneously with the bone ring technique. MATERIAL AND METHODS:Dental implants were inserted simultaneously with the bone ring technique in standardized, vertical alveolar bony defects in the mandible of d...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13543
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the outcomes of the installation of two implant-supported overdentures until such treatment is complete. Although this treatment is well established in the literature, there are no studies comparing what happens to muscles and the quality of life (QoL) of patients dur...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12980
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:To compare the effectiveness of free-handed (FH), pilot-drill guided (PG) and fully guided (FG) implant surgery by means of the apical global deviation (AGD) in relation to the additional financial cost and time spent. MATERIALS AND METHODS:Thirty-three partially edentulous patients in need of ≥2 implants i...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13399
更新日期:2019-02-01 00:00:00
abstract:AIM:The aim of this clinical trial was to evaluate the safety and efficiency of a one-piece zirconia oral implant after 1 year of function. MATERIALS AND METHODS:Two centers included 60 subjects in need of implant-supported single-tooth restorations or three-unit bridges. A total of 71 zirconia one-piece implants were...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/clr.12670
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To evaluate maximal occlusal bite forces (MOF) and marginal bone level (MBL) changes in patients with implant-tooth-supported fixed partial prostheses (FPP). MATERIAL AND METHODS:Twenty nine partially edentulous patients consecutively who received 34 three-occlusal unit FPP with terminal implant and tooth supp...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01169.x
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVES:To study the peri-implant bone organization pattern of immediately loaded (IL) zirconia implants with microgrooved surfaces. MATERIALS AND METHODS:Forty-eight dental implants of 4 mm diameter and 10 mm length were inserted after two months postextraction healing in the edentulous mandible of six dogs. Three...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12461
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVES:The aim of the present multi-center study was to evaluate the treatment outcome of immediately restored one-piece single-tooth implants with a diameter of 3 mm after 1 year. MATERIAL AND METHODS:A total of 57 one-piece implants (NobelDirect 3.0) were inserted in 47 patients (26 females, 21 males) with a mea...
journal_title:Clinical oral implants research
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1600-0501.2011.02174.x
更新日期:2012-01-01 00:00:00
abstract::Dental implant surfaces are important in determining the tissue/surface interaction. One of the first cells to adhere to the implant surface is the monocyte. This study examines the effect of surface roughness on monocyte adhesion and cytokine secretion. Monocyte adherence to titanium discs of 4 different degrees of s...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130111.x
更新日期:2002-02-01 00:00:00
abstract::The aim of the study was to evaluate two bioresorbable polylactic acid (PLA) filler materials in a guided bone regeneration (GBR) model system. The first was Polyfibre, a fibrous PLA filler material. Polyfoam, the second material tested, consisted of a spongy PLA filler material. In each group there were eight rabbits...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1046/j.0905-7161.2003.00930.x
更新日期:2003-12-01 00:00:00
abstract::The aim of this study was to determine the cell characteristics that regulate implant osseointegration. The heterogeneity of bone marrow stromal cells obtained from 11 donors was assessed by measuring the expression of a large panel of adhesion molecules. Large differences in expression of adhesion molecules were dete...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2003.00949.x
更新日期:2003-10-01 00:00:00
abstract::The purpose of the following study was to evaluate the medium- to long-term prognosis of implant-supported cantilever fixed prostheses, and to establish to what degree this is influenced by factors such as length, type of cantilever (mesial or distal), and opposite dentition versus cantilever prostheses. This study wa...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2003.120905.x
更新日期:2003-06-01 00:00:00
abstract::In a prospective study, 20 patients who underwent harvesting of chin grafts as outpatients, were followed up for 12 months (3 further patients with incomplete follow-up data were excluded from the study). Preoperatively and 7 days, 1, 3, 6 and 12 months postoperatively, follow-up data were assessed. Evaluation of the ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2001.120510.x
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVE:This short communication reports on a novel digital technique designated - the "Fully Digital Technique (FDT)" - to take the impression of the peri-implant soft tissue and emergence profile with an intraoral scanner, digitally capturing both the three dimensional position of the implant platform and the coron...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12599
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To compare the sequential healing at immediately loaded implants installed in a healed alveolar bony ridge or immediately after tooth extraction. MATERIAL AND METHODS:In the mandible of 12 dogs, the second premolars were extracted. After 3 months, the mesial roots of the third premolars were endodontically t...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12389
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the bone regenerative properties of a heat treated cross-linked GBR membrane with zinc hydroxyapatite powders in the rat calvarial defect model over a 6-week period. MATERIAL AND METHODS:In vitro physio-chemical characterization involved X-ray diffraction analysis, s...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12520
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:Peri-implant disease is considered to be an inflammatory disease, but many aspects of its pathogenesis remain unknown. At present, peri-implant disease is considered to be initiated and perpetuated by a small group of predominantly Gram-negative, anaerobic, or micro-aerophilic bacteria that colonize the subg...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2006.01296.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to test the retention of metal copings fabricated to fit on the one-groove, one flat-sided solid titanium abutment using six different cements. MATERIALS AND METHODS:Ten hollow screw 3.8 mm ITI implants were mounted in acrylic resin blocks. A solid titanium abutment was placed o...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130401.x
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the reliability and failure modes of regular and horizontal mismatched platforms for implant-abutment connection varying the implant diameter. MATERIAL AND METHODS:Regular (REG, n = 21, 4.0-mm-diameter implant) and horizontal mismatched (HM, n = 21, 4.6-mm-diameter implant) platform Ti-6Al-4V im...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2011.02257.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:This retrospective cross-sectional study aimed to evaluate the prevalence of biologic complications of implants in patients treated by fixed implant supported prosthesis without regular maintenance program. MATERIALS AND METHODS:One hundred thirty-four patients with 478 implants, installed during a 10-year ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12800
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Minimizing crestal bone loss following immediate implant placement is considered the most challenging aspect in implant therapy. Implant surface topography and chemical modifications have been shown to influence the success of Osseointegration. The Straumann Bone Level implant, featuring SLActive surface, ha...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12388
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:Minor sinus floor elevation is a method with relatively high predictability but is technically demanding. Improvement of the technique and increase in the predictability are desirable. MATERIAL AND METHODS:A clinical protocol for minor sinus floor elevation with SLA-ITI (large grit acid-etched implants with...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01161.x
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVES:The present study aimed at evaluating the marginal bone resorption and the peri-implant tissue conditions around Narrow-Neck ITI implants in the implant-prosthetic treatment of the agenesis of maxillary lateral incisors. MATERIAL AND METHODS:Thirty patients affected by monolateral or bilateral agenesis of t...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0501.2005.01188.x
更新日期:2006-02-01 00:00:00
abstract:UNLABELLED:Osseointegration failure is a complex, multifactorial trait shown to concentrate in some treated populations. There has been shown evidence for genetic contribution to dental implant loss. Genetic polymorphisms have been classically considered as genetic risk factors for several diseases and, more recently, ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2008.01532.x
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:A systematic review and meta-analysis are carried out to assess the scientific evidence that bisphosphonate therapy can decrease the success rate of dental implants. MATERIAL AND METHODS:The PubMed (Medline) database was used to search for articles published up until February 22, 2014. The meta-analysis was ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/clr.12526
更新日期:2016-02-01 00:00:00
abstract::Although a two-stage procedure with symphyseal oral implants can lead to a long-term (15 years) 99% cumulative survival rate, a one-stage approach with immediate loading via prefabricated elements seems to offer a short-term acceptable outcome with significantly lower costs. A series of 50 consecutive patients, not el...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01069.x
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:To evaluate implant survival rate, any complications, and changes in residual alveolar bone height (RABH) using saline or platelet-rich fibrin (PRF) filling after hydraulic transcrestal sinus lifting. METHODS:Dental implants were placed after hydraulic transcrestal sinus lifting and the filling of saline (2...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13655
更新日期:2020-11-01 00:00:00
abstract:AIM:The aim of this biomechanical study was to assess the influence of self-tapping blades in terms of primary implant stability between implants with self-tapping blades and implants without self-tapping blades using five different analytic methods, especially in medium-density bone. MATERIALS AND METHODS:Two differe...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02089.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate a new design of the cervical portion of dental implant with the objective to increase the volume of peri-implant tissues in the crestal area. MATERIALS AND METHODS:Forty-eight tapered dental titanium implants with internal conical connection were implanted in healed alve...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12978
更新日期:2018-07-01 00:00:00
abstract::The aim of the present study was to evaluate the effect of augmenting the maxillary alveolar ridge and the lateral aspect of the mandible with onlay autogeneic cortico-cancellous bone grafts that were covered with e-PTFE membranes. The experiment was carried out in 51 rats. In 15 rats, the edentulous maxillary jaw bet...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.2002.130210.x
更新日期:2002-04-01 00:00:00