Epilepsy, antiepileptic drugs and suicidality.

abstract：PURPOSE OF REVIEW:Campylobacter jejuni is the most frequent agent of antecedent infection in an axonal variant of Guillain-Barré syndrome, acute motor axonal neuropathy, and anti-GM1 or anti-GD1a IgG antibody is also associated with acute motor axonal neuropathy. Molecular mimicry has been found between human GM1 gangl...

journal_title：Current opinion in neurology

authors： Yuki N,Odaka M

更新日期：2005-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Neuroimaging in motor neuron disease (MND) has traditionally been seen as an academic tool with limited direct relevance to individualized patient care. This has changed radically in recent years as computational imaging has emerged as a viable clinical tool with true biomarker potential. This transit...

journal_title：Current opinion in neurology

authors： Bede P,Querin G,Pradat PF

更新日期：2018-08-01 00:00:00

abstract：:Ablative surgery and deep brain stimulation for Parkinson's disease can be performed in the thalamus, the pallidum and the subthalamic nucleus. The efficacy and safety of unilateral pallidotomy is well established. Deep brain stimulation has a lower morbidity and is preferred for bilateral surgery. The subthalamic nuc...

journal_title：Current opinion in neurology

authors： Krack P,Hamel W,Mehdorn HM,Deuschl G

更新日期：1999-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will summarize new neuroimaging techniques, particularly MRI and PET imaging, that can be used to assess brain tumor growth and angiogenesis. RECENT FINDINGS:Glioma tumor vasculature is abnormal, and advances in MRI now permit visualization of the hemodynamic properties of gliomas includi...

journal_title：Current opinion in neurology

authors： Gerstner ER,Sorensen AG,Jain RK,Batchelor TT

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The relative influence of genes and environment on the liability to neurodevelopmental disorders (NDDs) can be investigated using a twin design. This review highlights the results of the most recent twin studies of NDDs. RECENT FINDINGS:Recent twin studies have confirmed that NDDs show moderate-to-hi...

journal_title：Current opinion in neurology

authors： Posthuma D,Polderman TJ

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review some aspects of the relationship between epilepsy and depression that have recently received increasing attention and may become major research topics in the near future. RECENT FINDINGS:Epidemiological studies show that depression and suicide are, in some cases, premorbid symptoms precedin...

journal_title：Current opinion in neurology

authors： Mula M

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses advances in the understanding of the mechanisms of status epilepticus and its current treatment approaches. Many of these have been topics at the 5th London-Innsbruck Colloquium on status epilepticus 2015. RECENT FINDINGS:A new definition and classification of status epilepticus...

journal_title：Current opinion in neurology

authors： Trinka E,Brigo F,Shorvon S

更新日期：2016-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the major advances in inflammatory myopathies. RECENT FINDINGS:Polymyositis is an uncommon disorder that can be misdiagnosed when the old, and never validated, criteria of Bohan and Peter are used. New diagnostic criteria were recently introduced, in which the MHC/CD8 complex ...

journal_title：Current opinion in neurology

authors： Dalakas MC

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The funduscopic examination can be a technically difficult, and often omitted, portion of the neurologic examination, despite its great potential to influence patient care. RECENT FINDINGS:Medical practitioners are often first taught to examine the ocular fundus using a direct ophthalmoscope, however...

journal_title：Current opinion in neurology

authors： Rodenbeck SJ,Mackay DD

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review considers the role of neuroimaging in developmental disorders by highlighting recent studies in two distinct, but overlapping, developmental disorders: autism and fragile X syndrome. RECENT FINDINGS:After a decade of conflicting results in neuroimaging studies of autism, recent studies ha...

journal_title：Current opinion in neurology

authors： Greicius MD

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Valproic acid (VPA) is one of the four first line antiepileptic drugs (AEDs). VPA is also an effective drug in migraine prophylaxis and in treatment of bipolar disorders. The use of VPA is limited by its two rare but potentially life-threatening side effects, teratogenicity and hepatotoxicity, and it ...

journal_title：Current opinion in neurology

authors： Isoherranen N,Yagen B,Bialer M

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Stroke thrombolysis is in the process of moving from academic centers into community-based standard therapy in experienced centers. Recently published data on patient selection, imaging and other technical or organizational advances are reviewed in order to improve the safety and efficacy of stroke th...

journal_title：Current opinion in neurology

authors： Lindsberg PJ,Kaste M

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent terminations of clinical trials of myostatin inhibitors in muscular dystrophy have raised questions about the predictiveness of mouse models for this therapeutic strategy. RECENT FINDINGS:A variety of myostatin inhibitors have been developed for preclinical and clinical studies. These inhibito...

journal_title：Current opinion in neurology

authors： Wagner KR

更新日期：2020-10-01 00:00:00

abstract：:A review of the literature on methods of seizure or epilepsy severity assessments resulted in tabulation of the seizure rating scales known as US Department of Veterans Affairs (VA), Chalfont-National Hospital, Liverpool, Hague, and others. Each of the scales reviewed has some advantages, but none of them appears to b...

journal_title：Current opinion in neurology

authors： Cramer JA

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Herein we discuss the recent literature concerning cervicogenic vertigo including vertigo associated with rotational vertebral artery syndrome, as well as whiplash and degenerative disturbances of the cervical spine. We conclude with a summary of progress regarding diagnostic methods for cervicogenic ...

journal_title：Current opinion in neurology

authors： Hain TC

更新日期：2015-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the extensive research carried out in the past decades, the current pathophysiological notions of neurodegenerative disease as well as effective treatments to reduce their progression are largely unknown. Alterations of the human microbiota, the plethora of different microscopic organisms that...

journal_title：Current opinion in neurology

authors： Marizzoni M,Provasi S,Cattaneo A,Frisoni GB

更新日期：2017-12-01 00:00:00

abstract：:Three genetic loci for Alzheimer's disease have been identified. These are the amyloid precursor gene on chromosome 21, a gene for early-onset autosomal dominant Alzheimer's disease on chromosome 14, and the risk-modifying gene APOE on chromosome 19. Additional Alzheimer's disease genes remain to be found. The genes i...

journal_title：Current opinion in neurology

authors： Schellenberg GD

更新日期：1995-08-01 00:00:00

abstract：:Primary germ-cell tumors of the central nervous system are rare neoplasms that are seen primarily in the pediatric age group. Because of their frequent location in the pituitary and suprasellar regions, they present with typical neuro-ophthalmologic and neuroendocrine symptoms. Sophisticated imaging and surgical biops...

journal_title：Current opinion in neurology

authors： Hooda BS,Finlay JL

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The traditional focus of neurorehabilitaion has been on the patients' attention on their deficit, such that they should become aware of their problems and gain intentional control of compensatory strategies (descending approach). We review prism adaptation as one of the approaches that emphasize ascen...

journal_title：Current opinion in neurology

authors： Pisella L,Rode G,Farnè A,Tilikete C,Rossetti Y

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The cause of multiple sclerosis remains elusive. We review recent epidemiological studies of genetic and environmental factors that influence susceptibility to the disease and its clinical course. RECENT FINDINGS:Genetic advances strengthen the association of multiple sclerosis with the human leukocy...

journal_title：Current opinion in neurology

authors： Kantarci O,Wingerchuk D

更新日期：2006-06-01 00:00:00

abstract：:Stimulated by the impressive effect of interferon beta on magnetic resonance imaging-detected disease activity, the past year or so has seen a particular interest in the use of magnetic resonance imaging to monitor treatment. To be effective in this regard, there needs to be a high sensitivity and accuracy in detectin...

journal_title：Current opinion in neurology

authors： Miller DH

更新日期：1995-06-01 00:00:00

abstract：:Epilepsies, like other common diseases, have complex inheritance, and molecular genetic studies in such conditions are difficult. There has been recent success in identifying the molecular basis of certain epilepsies, particularly in those syndromes with autosomal dominant inheritance. All four genes discovered to dat...

journal_title：Current opinion in neurology

authors： Berkovic SF,Scheffer IE

更新日期：1999-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Drug resistance is an important clinical problem: it is associated with higher rates of somatic and psychiatric comorbidities and cognitive/memory decline, with seizures being just the 'tip of the iceberg'. This review summarizes recent developments in imaging research, focusing specifically on the fu...

journal_title：Current opinion in neurology

authors： Koepp MJ

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the most important issues a clinician must consider whenever selecting and administering antiepileptic drugs (AEDs). There is no available algorithm that identifies how to individualize selection of AEDs. Proper selection and administration can make an enormous difference in both effective...

journal_title：Current opinion in neurology

authors： Cheng JY,French JA

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Cervical artery dissection (CeAD) is a major cause of ischemic stroke in young and middle-aged adults, although relatively uncommon in the community. Recent large collaborative projects have provided new insights into mechanisms and risk factors of CeAD. RECENT FINDINGS:Pathologic changes observed at...

journal_title：Current opinion in neurology

authors： Debette S

更新日期：2014-02-01 00:00:00

abstract：:Autoimmune ataxic neuropathies are a subset of the sensory ataxic neuropathies which are characterized by ataxia as the dominant presenting feature. The major known causes of autoimmune ataxic neuropathies include sensory variants of the Guillain-Barré syndrome, including Miller-Fisher syndrome, subsets of immunoglobu...

journal_title：Current opinion in neurology

authors： O'Leary CP,Willison HJ

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Hyperglycemia is frequent in patients with cerebrovascular disease. This review article aims to summarize the recent evidence from observational studies that examined the adverse cerebrovascular effects of dysglycemic states as well as interventional studies assessing intensive management strategies f...

journal_title：Current opinion in neurology

authors： Haratz S,Tanne D

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Precise localization of the epileptogenic zone is imperative for the success of resective surgery of drug-resistant epileptic patients. To decrease the number of surgical failures, clinical research has been focusing on finding new biomarkers. For the past decades, high-frequency oscillations (HFOs, 8...

journal_title：Current opinion in neurology

authors： Roehri N,Bartolomei F

更新日期：2019-04-01 00:00:00

abstract：:This paper reviews clinical reports of various movement disorders (dystonia, chorea, ballism and parkinsonism) caused by well defined lesions of the putamen, globus pallidus, substantia nigra, thalamus and subthalamus. The role of basal ganglia in motor control is also emphasized. ...

journal_title：Current opinion in neurology

authors： Berardelli A

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the background, principles and implementation of the Stroke Action Plan for Europe 2018--2030 (SAP-E) in the perspective of the current COVID-19 pandemic. RECENT FINDINGS:SAP-E sets targets for the implementation of evidence-based preventive actions and stroke services to 2030. A recent m...

journal_title：Current opinion in neurology

authors： Christensen H,Pezzella FR,Action Plan for Stroke in Europe Implementation Steering Committee.

更新日期：2021-02-01 00:00:00