当前位置： SCI文献检索 > JOURNAL OF CLINICAL EPIDEMIOLOGY期刊下所有文献 > High validity of mother-reported use of antiasthmatics among children: a comparison with a population-based prescription database.

High validity of mother-reported use of antiasthmatics among children: a comparison with a population-based prescription database.

Abstract：

OBJECTIVES:To examine the validity of (1) maternal questionnaire report of children's use of antiasthmatics using a prescription database as the reference standard and (2) dispensed antiasthmatics as a measure of asthma using maternal report of children's asthma as the reference standard. STUDY DESIGN AND SETTING:A total of 3,394 children in the Norwegian Mother and Child Cohort Study aged 7 years were linked to the Norwegian Prescription Database. Maternal report of both children's use of antiasthmatics during the preceding year and the presence of asthma was compared with data on dispensed antiasthmatics. RESULTS:A total of 2,056 mothers responded and reported use of antiasthmatics during the previous year in 125 of 147 children who had been dispensed antiasthmatics (sensitivity 85.0%). Of the 1,909 children with no dispensed antiasthmatics, 1,848 had no maternal report of antiasthmatic use (specificity 96.8%). Mothers reported current asthma in 133 (6.5% of 2,056) children, including in 122 (5.9%) reported as verified by a doctor. Of these 122, 98 had been dispensed antiasthmatics during the preceding year (sensitivity 80.3%). Only 1.2% of the children without reported asthma were dispensed antiasthmatics. CONCLUSION:Mother-reported use of antiasthmatics during the previous year among 7-year-old children is highly valid. Dispensed antiasthmatics would be a useful proxy for the presence of current asthma when disease data are not available.

journal_name

J Clin Epidemiol

journal_title

Journal of clinical epidemiology

authors

Furu K,Karlstad Ø,Skurtveit S,Håberg SE,Nafstad P,London SJ,Nystad W

doi

10.1016/j.jclinepi.2010.10.014

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

878-84

issue

8

eissn

0895-4356

issn

1878-5921

pii

S0895-4356(10)00379-3

journal_volume

64

pub_type

杂志文章

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