The analysis of case-control studies of the efficacy of screening for recurrence of cancer.


:Occasionally, the efficacy of screening for cancer recurrence has been evaluated by means of case-control studies. However, these studies generally have not been designed and analyzed in a manner that will yield an unbiased result. The commentary shows that by adhering to the principles developed for the analysis of studies of the efficacy of screening for the presence of a given cancer in persons with no history of this disease, a case-control study of screening for recurrence will improve its chances of obtaining valid findings.


J Clin Epidemiol


Weiss NS




Has Abstract


2011-01-01 00:00:00














  • Screening with total cholesterol: determining sensitivity and specificity of the National Cholesterol Education Program's guidelines from a population survey.

    abstract::The objective of the study was to determine the sensitivity and specificity of the National Cholesterol Education Program (NCEP) guidelines in identifying at-risk individuals for hypercholesterolemia, using population-based data from the Manitoba Heart Health Survey (MHHS). The MHHS surveyed a representative sample of...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Gelskey DE,Young TK,MacDonald SM

    更新日期:1994-05-01 00:00:00

  • External validation of prognostic models for critically ill patients required substantial sample sizes.

    abstract:OBJECTIVE:To investigate the behavior of predictive performance measures that are commonly used in external validation of prognostic models for outcome at intensive care units (ICUs). STUDY DESIGN AND SETTING:Four prognostic models (Simplified Acute Physiology Score II, the Acute Physiology and Chronic Health Evaluati...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Peek N,Arts DG,Bosman RJ,van der Voort PH,de Keizer NF

    更新日期:2007-05-01 00:00:00

  • The qualification period.

    abstract::For randomized trials that do not require prompt onset of therapy, a pre-admission preparation, called the qualification period, can deal with certain customary difficulties in design, analysis, and ethics. For the patients' baseline state, the qualification period can be used to "wash out" effects of previous treatme...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Knipschild P,Leffers P,Feinstein AR

    更新日期:1991-01-01 00:00:00

  • Present-at-admission diagnoses improved mortality risk adjustment among acute myocardial infarction patients.

    abstract:OBJECTIVE:Hospital mortality outcomes for acute myocardial infarction (AMI) patients are a focus of quality improvement programs conducted by government agencies. AMI mortality risk-adjustment models using administrative data typically adjust for baseline differences in mortality risk with a limited set of common and d...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Stukenborg GJ,Wagner DP,Harrell FE Jr,Oliver MN,Heim SW,Price AL,Han CK,Wolf AM,Connors AF Jr

    更新日期:2007-02-01 00:00:00

  • Incremental cost-effectiveness analysis: the optimal strategy depends on the strategy set.

    abstract::Evaluating the incremental cost-effectiveness of a technology is critical to understanding the impact of its adoption. The purpose of this study was to evaluate, using a particular example, how the specific alternatives selected for a cost-effectiveness analysis may influence the results of the analysis. In this examp...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Cantor SB,Ganiats TG

    更新日期:1999-06-01 00:00:00

  • A reliable and valid index was developed to measure appropriate psychotropic drug use in dementia.

    abstract:OBJECTIVES:The aim of this study was to develop an index derived from the Medication Appropriateness Index (MAI) items that is suited for clinical studies evaluating appropriateness of psychotropic drug use (PDU) for neuropsychiatric symptoms (NPS) in patients with dementia in nursing homes and to test its reliability ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: van der Spek K,Gerritsen DL,Smalbrugge M,Nelissen-Vrancken MH,Wetzels RB,Smeets CH,Zuidema SU,Koopmans RT

    更新日期:2015-08-01 00:00:00

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    abstract::In the Upper Bavarian Field Study a total of 1536 persons (15 years and older) were interviewed by research psychiatrists. 8.1% of all respondents took a psychotropic drug during the 7 days prior to the interview. The consumption rate among women was about three times as high as that for men. The use of psychotropic d...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Weyerer S,Dilling H

    更新日期:1991-01-01 00:00:00

  • Patterns of intra-cluster correlation from primary care research to inform study design and analysis.

    abstract:OBJECTIVE:To provide information concerning the magnitude of the intraclass correlation coefficient (ICC) for cluster-based studies set in primary care. STUDY DESIGN AND SETTING:Reanalysis of data from 31 cluster-based studies in primary care to estimate intraclass correlation coefficients from random effects models u...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,meta分析,评审


    authors: Adams G,Gulliford MC,Ukoumunne OC,Eldridge S,Chinn S,Campbell MJ

    更新日期:2004-08-01 00:00:00

  • The statistical significance of meta-analyses is frequently fragile: definition of a fragility index for meta-analyses.

    abstract:OBJECTIVES:Meta-analyses inform clinical practice by summarizing treatment effect estimates based on results from several trials. However, the statistical significance of a meta-analysis (i.e., whether the pooled treatment effect is statistically significant or not) may rely on the outcome of only a few patients from s...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Atal I,Porcher R,Boutron I,Ravaud P

    更新日期:2019-07-01 00:00:00

  • Changing the behavior of healthcare professionals: the use of theory in promoting the uptake of research findings.

    abstract:OBJECTIVE:The uptake of research findings into routine health care is a haphazard and unpredictable process. The usefulness of the results of implementation studies is limited, due in part to the lack of an underlying framework of the important dimensions of research studies in this area and the healthcare settings wit...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Eccles M,Grimshaw J,Walker A,Johnston M,Pitts N

    更新日期:2005-02-01 00:00:00

  • OAKHQOL: a new instrument to measure quality of life in knee and hip osteoarthritis.

    abstract:OBJECTIVE:To develop a questionnaire with which to measure quality of life (QoL) in patients with knee and hip osteoarthritis (OA). STUDY DESIGN AND SETTING:Thirty-two caregivers and 96 OA patients were interviewed individually (using cognitive and face-to-face techniques) and in focus groups. A group of experts worki...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,多中心研究


    authors: Rat AC,Coste J,Pouchot J,Baumann M,Spitz E,Retel-Rude N,Le Quintrec JS,Dumont-Fischer D,Guillemin F

    更新日期:2005-01-01 00:00:00

  • Parity derived for pregnant women using historical administrative hospital data: accuracy varied among patient groups.

    abstract:OBJECTIVES:Understanding patterns of maternity care requires knowing which women have given birth previously, but this information is typically unavailable in administrative hospital data sets. We assessed how well parity can be derived using linked historical records. STUDY DESIGN AND SETTING:Using Hospital Episode S...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Cromwell DA,Knight HE,Gurol-Urganci I

    更新日期:2014-05-01 00:00:00

  • Using decision thresholds for ranking treatments in network meta-analysis results in more informative rankings.

    abstract:OBJECTIVES:To evaluate how the rank probabilities obtained from network meta-analysis (NMA) change with the use of increasingly stringent criteria for the relative effect comparing two treatments which ranks one treatment better than the other. STUDY DESIGN AND SETTING:Systematic survey and reanalysis of published dat...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Brignardello-Petersen R,Johnston BC,Jadad AR,Tomlinson G

    更新日期:2018-06-01 00:00:00

  • An analysis of administrative data found that proximate clinical event ratios provided a systematic approach to identifying possible iatrogenic risk factors or complications.

    abstract:OBJECTIVE:A method to generate hypotheses about iatrogenic risk factors and complications from administrative data was developed and tested using hospitalization of the elderly for depression as a model. STUDY DESIGN AND SETTING:Hospital claims were selected for 30,998 elderly inpatients admitted for the first time fo...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Baine WB,Kazakova SV

    更新日期:2005-02-01 00:00:00

  • Correlation between serial tests made disease probability estimates erroneous.

    abstract:BACKGROUND:The probability of a disease, given the result of two diagnostic tests, can be calculated by multiplying the odds of disease after the first test by the likelihood ratio of the second test. OBJECTIVE:To illustrate the error that occurs when calculating disease probability by combining the results of tests t...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: van Walraven C,Austin PC,Jennings A,Forster AJ

    更新日期:2009-12-01 00:00:00

  • Relationships of site of infarction and history of previous infarction with short- and long-term prognosis after acute myocardial infarction in Japan.

    abstract::We studied the outcome in 308 patients with acute myocardial infarction (MI) admitted to the coronary care unit of Kobe General Hospital. Short-term outcome (within 28 days after MI) and long-term outcome (more than 28 days) were examined with survival curves to find any relationship with a history of previous MI and ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Nishi N,Nakanishi N,Kuroda K,Koizumi K,Yoshikawa J,Tatara K

    更新日期:1992-01-01 00:00:00

  • Different methods to assess quality of life from multiple follow-ups in a longitudinal asthma study.

    abstract:BACKGROUND AND OBJECTIVE:Serial measurements obtained during observational longitudinal studies offer the opportunity to describe the effects of chronic diseases on patient-centered outcomes such as quality of life. The purpose of this study was to assess serial Asthma Quality of Life Questionnaire (AQLQ) and SF-36 sco...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Mancuso CA,Peterson MG

    更新日期:2004-01-01 00:00:00

  • Stratified randomization for clinical trials.

    abstract::Trialists argue about the usefulness of stratified randomization. For investigators designing trials and readers who use them, the argument has created uncertainty regarding the importance of stratification. In this paper, we review stratified randomization to summarize its purpose, indications, accomplishments, and a...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审


    authors: Kernan WN,Viscoli CM,Makuch RW,Brass LM,Horwitz RI

    更新日期:1999-01-01 00:00:00

  • Gender differences in the reliability of reporting symptoms of angina pectoris.

    abstract::Numerous studies have shown that the symptoms of angina pectoris are more prevalent in women than men, than other manifestations of coronary heart disease, with the greatest discrepancies at younger ages. Variation in symptom reliability between genders could be a potential explanation for these differences. The Lipid...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Harris RB,Weissfeld LA

    更新日期:1991-01-01 00:00:00

  • Pain and pain treatment were associated with traffic accident involvement in a cohort of middle-aged workers.

    abstract:BACKGROUND AND OBJECTIVE:To assess the influence of medical conditions on road traffic accidents among a cohort of middle-aged workers and pensioners. STUDY DESIGN AND SETTING:A longitudinal study of 13,548 participants from a cohort study of French workers. Follow-up data covered the 1989-2000 period. Adjusted hazard...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Lagarde E,Chastang JF,Lafont S,Coeuret-Pellicer M,Chiron M

    更新日期:2005-05-01 00:00:00

  • Using the STROBE statement: survey findings emphasized the role of journals in enforcing reporting guidelines.

    abstract:OBJECTIVES:The objective of the study was to identify factors affecting the use of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement, specifically authors' attitudes toward and experiences with it. STUDY DESIGN AND SETTING:An online survey was distributed to authors of observa...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Sharp MK,Bertizzolo L,Rius R,Wager E,Gómez G,Hren D

    更新日期:2019-12-01 00:00:00

  • Fracture risk following bilateral oophorectomy.

    abstract::To assess fracture risk following bilateral oophorectomy, we conducted a population-based retrospective cohort study among the 463 Rochester, Minnesota women who underwent bilateral oophorectomy for benign ovarian conditions in 1950-1979. During 7220 person-years of observation, there appeared to be a modest increase ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Melton LJ 3rd,Crowson CS,Malkasian GD,O'Fallon WM

    更新日期:1996-10-01 00:00:00

  • Comparative responsiveness of generic and specific quality-of-life instruments.

    abstract::We assessed the relative responsiveness of generic and specific quality of life instruments in 43 randomized controlled trials that compared head-to-head 31 generic and 84 specific instruments. Using weighted effect size as the metric of responsiveness, we assessed the impact of instrument type, disease category, and ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审


    authors: Wiebe S,Guyatt G,Weaver B,Matijevic S,Sidwell C

    更新日期:2003-01-01 00:00:00

  • Toxic oil syndrome: survival in the whole cohort between 1981 and 1995.

    abstract:BACKGROUND AND OBJECTIVE:In 1981, toxic oil syndrome (TOS) appeared in Spain, affecting more than 20,000 persons and causing over 2500 deaths to date. Previous studies have addressed mortality only by gender and age. We analyzed possible prognostic factors in the survival of the cohort. METHODS:The study period was 1 ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Sánchez-Porro Valadés P,Posada de la Paz M,de Andrés Copa P,Gimenez Ribota O,Abaitua Borda I

    更新日期:2003-07-01 00:00:00

  • Validation of the Danish Birth Registration.

    abstract::We assessed validity and reliability of data on four serious pregnancy complications and gestational age in two national registers, the Medical Birth Register (MBR) and the National Register of Hospital Discharges (NRHD). From a cohort of all women in Denmark who gave birth to their first and second singleton infant i...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Kristensen J,Langhoff-Roos J,Skovgaard LT,Kristensen FB

    更新日期:1996-08-01 00:00:00

  • Postmenopausal estrogen use and invasive versus in situ breast cancer risk.

    abstract::To examine the effect of cancer histopathology on the relationship between estrogen-replacement therapy (ERT) use and breast cancer risk, we performed a case-control study of 109 postmenopausal women 45 years or older with in situ or invasive breast cancer matched to 545 controls. When in situ and invasive tumors were...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Henrich JB,Kornguth PJ,Viscoli CM,Horwitz RI

    更新日期:1998-12-01 00:00:00

  • Alcohol drinking and bladder cancer.

    abstract::The relation between alcoholic beverage consumption and bladder cancer risk was investigated using data from a case-control study conducted between 1985 and 1992 in two areas of northern Italy. Cases were 727 patients with incident, histologically confirmed bladder cancer, and controls 1,067 patients admitted to the s...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,多中心研究


    authors: Pelucchi C,Negri E,Franceschi S,Talamini R,La Vecchia C

    更新日期:2002-07-01 00:00:00

  • Cherry-picking by trialists and meta-analysts can drive conclusions about intervention efficacy.

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    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审


    authors: Mayo-Wilson E,Li T,Fusco N,Bertizzolo L,Canner JK,Cowley T,Doshi P,Ehmsen J,Gresham G,Guo N,Haythornthwaite JA,Heyward J,Hong H,Pham D,Payne JL,Rosman L,Stuart EA,Suarez-Cuervo C,Tolbert E,Twose C,Vedula S,Dicke

    更新日期:2017-11-01 00:00:00

  • A prospective study of psychological and socioeconomic characteristics, health behavior and morbidity in cigarette smokers prior to quitting compared to persistent smokers and non-smokers.

    abstract::Psychosocial factors influencing smoking cessation were studied in current smokers prior to quitting. Two questionnaires were sent in 1975 and 1981 to adult members of the Finnish Twin Cohort. The 1975 response rate was 89%, and 89% of those eligible replied again in 1981. Analysis was done on data from one twin pair ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Kaprio J,Koskenvuo M

    更新日期:1988-01-01 00:00:00

  • Cross-cultural adaptation of Roland-Morris Disability Questionnaire needs to assess the measurement properties: a systematic review.

    abstract:OBJECTIVE:To assess the cross-cultural adaptations of the Roland-Morris Disability Questionnaire (RMDQ). STUDY DESIGN AND SETTING:English and Chinese databases were searched through December 2017. Cross-cultural adaptation and measurement properties were evaluated using the Guidelines for the Process of Cross-Cultural...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章


    authors: Yao M,Zhu S,Tian ZR,Song YJ,Yang L,Wang YJ,Cui XJ

    更新日期:2018-07-01 00:00:00