Abstract:
:The LiDCO plus monitor (LiDCO Ltd, Cambridge, UK) uses pulse contour analysis of the arterial pressure waveform to indicate changes in stroke volume and cardiac output. Calibration against a lithium indicator dilution method is required to permit display of absolute values in addition to trends. The effect of haemodynamic changes during anaesthesia and surgery on this calibration factor has not previously been studied. Therefore, we investigated whether it remained constant during elective abdominal aortic aneurysm surgery in 15 patients. Comparison between the calibration factor values at different time points was made by repeated recalibration throughout the peri-operative period. Calibration factor increased by a mean of 53% after anaesthesia (epidural plus general) (p = 0.03) and decreased by a mean of 40% after aortic clamping (p = 0.0001). Recalibration should be undertaken after induction of anaesthesia and after aortic clamping if absolute values of cardiac output and stroke volume are required.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Beattie C,Moores C,Thomson AJ,Nimmo AFdoi
10.1111/j.1365-2044.2010.06558.xsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
1194-9issue
12eissn
0003-2409issn
1365-2044journal_volume
65pub_type
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