Can esmolol manage surgically-induced tachycardia? Bolus esmolol treatment of intra-operative tachycardia due to surgical stimulation.


:A double-blind, randomised study was conducted to examine the efficacy of a single bolus dose of esmolol in treating surgically-induced tachycardia. Anaesthetic technique was identical in all patients, and consisted of premedication with midazolam and glycopyrronium, induction with thiopentone followed by suxamethonium, tracheal intubation, and maintenance with isoflurane 0.6% (end-tidal) and 60% nitrous oxide in oxygen. Forty-eight patients developed a heart rate of greater than 95 beats/minute or 20% more than pre-induction values at an average time of 34 minutes after tracheal intubation and received placebo (15 patients), esmolol 50 mg (16 patients), or esmolol 100 mg (17 patients). Controlled intervention was instituted if heart rate or blood pressure was not adequate. Both 50 and 100 mg of esmolol resulted in lower heart rates compared to placebo (p less than 0.05), with no difference between the two esmolol groups (p greater than 0.05). Patients who received placebo had more episodes of medical intervention than those given esmolol (p less than 0.05). No adverse effects occurred in any patient.






Whirley-Diaz J,Gold MI,Helfman SM,deLisser EA




Has Abstract


1991-03-01 00:00:00












  • Diagnostic accuracy of anaesthesiologists' prediction of difficult airway management in daily clinical practice: a cohort study of 188 064 patients registered in the Danish Anaesthesia Database.

    abstract::Both the American Society of Anesthesiologists and the UK NAP4 project recommend that an unspecified pre-operative airway assessment be made. However, the choice of assessment is ultimately at the discretion of the individual anaesthesiologist. We retrieved a cohort of 188 064 cases from the Danish Anaesthesia Databas...


    pub_type: 杂志文章


    authors: Nørskov AK,Rosenstock CV,Wetterslev J,Astrup G,Afshari A,Lundstrøm LH

    更新日期:2015-03-01 00:00:00

  • Compartment syndrome associated with the Lloyd Davies position. Three case reports and review of the literature.

    abstract::The Lloyd Davies position was developed to facilitate access to the pelvis for gynaecological, urological and colorectal procedures. Previous case reports have demonstrated that prolonged adoption (> 4 h) of this position has been associated with the development of bilateral compartment syndrome of the calves. All thr...


    pub_type: 杂志文章,评审


    authors: Turnbull D,Mills GH

    更新日期:2001-10-01 00:00:00

  • Anaesthetic staffing in England and Wales.

    abstract::The numbers of anaesthetists and of surgeons in the English Health Regions and in Wales as at September 1978, are given in whole-time equivalents per 100,000 of population. All Regional figures are presented as percentages of the national average so that comparisons between Regions can be made. Marked inter-Regional d...


    pub_type: 杂志文章


    authors: Rees LT

    更新日期:1980-11-01 00:00:00

  • Colloid osmotic pressure.

    abstract::Technical advances have made the bedside measurement of colloid osmotic pressure (COP) a rapid and reproducible test. The principles of measurement are described and the place of COP determinations in the recognition, treatment and prophylaxis of oedematous states is discussed. ...


    pub_type: 杂志文章,评审


    authors: Bevan DR

    更新日期:1980-03-01 00:00:00

  • Effect of amniotic fluid on coagulation and platelet function in pregnancy: an evaluation using thromboelastography.

    abstract::Amniotic fluid embolism is a rare obstetric complication. The exact pathogenesis of this syndrome remains unknown and significant controversy exists whether coagulopathy should always be present. We used thromboelastography to assess the effect of amniotic fluid on coagulation and platelet function in pregnant women. ...


    pub_type: 杂志文章


    authors: Harnett MJ,Hepner DL,Datta S,Kodali BS

    更新日期:2005-11-01 00:00:00

  • Postdural puncture symptoms in a child.

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    pub_type: 杂志文章


    authors: McHale J,O'Donovan FC

    更新日期:1997-07-01 00:00:00

  • Undiagnosed adult diastematomyelia associated with neurological symptoms following spinal anaesthesia.

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    pub_type: 杂志文章


    authors: Wenger M,Hauswirth CB,Brodhage RP

    更新日期:2001-08-01 00:00:00

  • Tramadol for prevention of postanaesthetic shivering: a randomised double-blind comparison with pethidine.

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    pub_type: 杂志文章,随机对照试验


    authors: Mohta M,Kumari N,Tyagi A,Sethi AK,Agarwal D,Singh M

    更新日期:2009-02-01 00:00:00

  • Sedation for oocyte retrieval using target controlled infusion of propofol and incremental alfentanil delivered by non-anaesthetists.

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    pub_type: 杂志文章


    authors: Edwards JA,Kinsella J,Shaw A,Evans S,Anderson KJ

    更新日期:2010-05-01 00:00:00

  • Evaluation of cardiac output in intensive care using a non-invasive arterial pulse contour technique (Nexfin(®)) compared with echocardiography.

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    pub_type: 杂志文章


    authors: Taton O,Fagnoul D,De Backer D,Vincent JL

    更新日期:2013-09-01 00:00:00

  • Neostigmine after spontaneous recovery from neuromuscular blockade. Effect on depth of blockade monitored with train-of-four and tetanic stimuli.

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    pub_type: 杂志文章


    authors: Goldhill DR,Wainwright AP,Stuart CS,Flynn PJ

    更新日期:1989-04-01 00:00:00

  • Hypophosphataemia and its consequences in patients following open heart surgery.

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    pub_type: 杂志文章


    authors: Swaminathan R,Morgan DB,Ionescu M,Hill GL

    更新日期:1978-07-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Singh P,Harwood R,Cartwright DP,Crossley AW

    更新日期:1994-11-01 00:00:00

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    pub_type: 杂志文章,评审


    authors: Lee JJ,Rubin AP

    更新日期:1993-07-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Wilson KE,Welbury RR,Girdler NM

    更新日期:2002-09-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Stuart JC,Kan AF,Rowbottom SJ,Yau G,Gin T

    更新日期:1996-05-01 00:00:00

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    pub_type: 杂志文章


    authors: Zorab JS,Fox DE

    更新日期:1977-11-01 00:00:00

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Chambers N,Lopez T,Thomas J,James MF

    更新日期:2002-02-01 00:00:00

  • Anaesthesia equipment malfunction.

    abstract::Anaesthetic equipment was studied to determine whether the accuracy was improved and failure rate decreased by routine maintenance and calibration by a biomedical technician. Each piece was evaluated, and then repaired and rechecked at intervals by the same technician. Equipment failures were divided into three types:...


    pub_type: 杂志文章


    authors: Holley HS,Carroll JS

    更新日期:1985-01-01 00:00:00

  • Awake fibreoptic intubation in the semi-prone position following facial trauma.

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    pub_type: 杂志文章


    authors: Neal MR,Groves J,Gell IR

    更新日期:1996-11-01 00:00:00

  • Nifedipine and surgical removal of phaeochromocytoma.

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    pub_type: 杂志文章


    authors: Chari P,Katariya RN,Venkataraman RK,Trikha A

    更新日期:1988-09-01 00:00:00

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    pub_type: 杂志文章


    authors: Suehiro K,Tanaka K,Yamada T,Matsuura T,Funao T,Mori T,Nishikawa K

    更新日期:2015-02-01 00:00:00

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    pub_type: 杂志文章


    authors: Houghton IT

    更新日期:2003-10-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 杂志文章,评审


    authors: White SM

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    pub_type: 杂志文章


    authors: Cahill JF

    更新日期:1981-08-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Hui MT,Subash S,Wang CY

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    pub_type: 杂志文章


    authors: Sajjad T,Ryan TD

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    pub_type: 杂志文章


    authors: Berridge JC,Warring-Davies K,Bland JM,Quinn AC

    更新日期:2009-09-01 00:00:00