Abstract:
OBJECTIVES:To evaluate clinical predictors of poor sleep quality and quality of life (QOL) in patients with hypertrophic cardiomyopathy (HCM). METHODS:Consecutive stable patients with HCM were evaluated for the risk of obstructive sleep apnea (OSA) by the Berlin Questionnaire, daytime sleepiness by the Epworth Sleepiness Scale, sleep quality by the Pittsburgh Sleep Questionnaire Index and QOL by the Minnesota Living with Heart Failure Questionnaire. Asymptomatic subjects without HCM were used as controls. RESULTS:We studied 84 patients with HCM and 42 controls who were similar with regard to gender (49 vs. 50% males), age [52 (38-62) vs. 47 (33-58) years] and body mass index (27 ± 4 vs. 27 ± 5). HCM diagnosis, high risk for OSA and female gender were independently associated with poor sleep quality in the entire population. Among patients with HCM, poor QOL was independently associated with poor sleep quality, New York Heart Association functional class and diuretic therapy. CONCLUSION:Poor sleep quality is very common in patients with HCM and may have a negative impact on the QOL, which in turn is an important marker of prognosis in patients with cardiomyopathies.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Pedrosa RP,Lima SG,Drager LF,Genta PR,Amaro AC,Antunes MO,Arteaga E,Mady C,Lorenzi-Filho Gdoi
10.1159/000321718subject
Has Abstractpub_date
2010-01-01 00:00:00pages
200-6issue
3eissn
0008-6312issn
1421-9751pii
000321718journal_volume
117pub_type
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