Abstract:
OBJECTIVES:Arsine, a potent hemolytic agent, is widely used in the semiconductor industry. We report a case of arsine poisoning confirmed by arsenic speciation analysis in serum and urine that occurred in a recycling factory. CASE:A male worker in his twenties noticed hematuria 3 h after finishing work and was admitted into our hospital 34 h later. Speciation analysis of arsenics in serum and urine samples was performed using HPLC-ICP-MS. On admission, anemia, hematuria, and renal and liver dysfunction were observed. His clinical condition had improved remarkably after 5-days of transfusion and 4 units of RBC transfusion. The total arsenic content in the serum was 244.8 µg/l at admission and 97.1 µg/l at discharge. In the speciation analysis, four kinds of As compounds derived from arsine metabolism were detected in serum and urine. The concentrations of arsenite (AsIII), arsenate (AsV), monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in serum at admission were 45.8, 5.2, 17.9 and 9.3 µg/l, respectively. The concentrations of AsIII, AsV and MMA decreased with biological half-lives (BHL) of 30.1, 43.0, and 96.3 h, respectively, while that of DMA was increased towards discharge. The urinary AsIII, AsV, MMA, and DMA concentrations at discharge were 384.5, 20.8, 547.4 and 1816.3 µg/g creatinine, respectively. These concentrations in urine subsequently decreased and their BHL was 15 days. CONCLUSION:The results of the present study suggest that arsine is quickly metabolized to AsIII and then metabolized via MMA to DMA in humans.
journal_name
J Occup Healthjournal_title
Journal of occupational healthauthors
Yoshimura Y,Endo Y,Shimoda Y,Yamanaka K,Endo Gdoi
10.1539/joh.l10108subject
Has Abstractpub_date
2011-01-01 00:00:00pages
45-9issue
1eissn
1341-9145issn
1348-9585pii
JST.JSTAGE/joh/L10108journal_volume
53pub_type
杂志文章abstract:OBJECTIVES:The aims of this study were to develop approaches for monitoring and prioritizing factors associated with thermal stresses imposed on workers in iron and steel casting industries, and to eventually purpose effective control strategies. METHODS:The whole study was completed in the furnace areas of two steel ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.14-0078-FS
更新日期:2014-01-01 00:00:00
abstract::Healthcare workers (HCWs) are exposed daily to the risk of injury by needlesticks and other medical instruments. However, the psychiatric impacts of such injuries have not been evaluated. The aim of this study was to evaluate the mental health status of HCWs with experiences of needlestick and sharps injuries. A cross...
journal_title:Journal of occupational health
pub_type: 杂志文章,多中心研究
doi:10.1539/joh.48.474
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVES:In order to measure occupational exposure concentrations of ethyl tertiary-butyl ether (ETBE), we developed a diffusive sampling method for monitoring ETBE and performed an ETBE exposure assessment. METHODS:The applicability of diffusive samplers was examined by exposing the samplers to ETBE vapor in test c...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0111-oa
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:The present study examined how job demands affect an intimate partner's well-being. We hypothesized that job demands have a negative influence on partner well-being through the experience of work-family conflict (WFC) and an impaired quality of the relationship (reduced social support and increased social un...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l8160
更新日期:2009-01-01 00:00:00
abstract::Sleep Apnea Syndrome (SAS) is a condition characterized by sleep-disordered breathing resulting in health impairment and sleep problems. From the viewpoints of the prevention of health impairment, accidents at work and traffic accidents, active implementation of screening for SAS in workplaces is necessary. Using a po...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.49.1
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine ultraviolet (UV) action spectra for cell killing of primary porcine lens epithelial cells (LECs) that can be used to establish guidelines for evaluation of the hazard of cataract due to UV exposure in the workplace. METHODS:Primary porcine LECs were exposed to differen...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0215-oa
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVES:The current study was performed to (1) understand the distribution of airborne fungi culturable on dichloran-glycerol agar (DG18) media over a one-year monitoring period, (2) identify the types of airborne fungi collected, and (3) compare and contrast under- and above-ground spaces, in two railway stations i...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.o9022
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:Nickel oxide nanoparticles (NiONPs) are representative metal oxide NPs and are categorized as an insoluble nickel compound. Our previous studies suggested that NiONPs have more pulmonary toxicity than micron-sized NiO because they may dissolve slowly and produce many more Ni ions. We confirmed the hypothesis ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1002/1348-9585.12162
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to examine changes in working hours, shift work, psychological and physical job demands, job control and job insecurity in Taiwanese employees by gender and age during the period of 2001 to 2010. METHODS:The study subjects were 36,750 men and 27,549 women, aged 25-64, from 4 rounds ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.12-0286-oa
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Petrochemical industries are known as sources of many toxic chemicals. Safety and health risks of the petrochemical workers employed at Map Ta Phut Industrial Estate, located in Rayong, Thailand, are potentially high. METHODS:The research materials consisted of documents emanating from statutory reports on ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.11-0091-oa
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:This study investigated potential associations between having a person in need of nursing care at home and psychological distress amongst the Japanese working population, using a nationally representative sample. METHODS:We extracted data from the 2013 Comprehensive Survey of Living Conditions conducted by ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2017-0295-OA
更新日期:2018-11-27 00:00:00
abstract:OBJECTIVES:Occupational lead (Pb) exposure is still an important health problem in the world. Long-term Pb exposure causes several adverse effects. The aim of this study was to investigate the changes of inflammation markers with chronic Pb exposure by analyzing neopterin levels and kynurenine (Kyn) to tryptophan (Trp)...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0273-OA
更新日期:2017-07-27 00:00:00
abstract::In Japan, consultations concerning child abuse cases are increasing rapidly, and the mental health of child-counseling office workers, who must deal with them, has emerged as an issue. To measure the state of mental health of these workers, and to clarify the characteristics of their job-related stress, we sent a ques...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.49.125
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:This report reviews the carcinogenicity of multi-walled carbon nanotubes (MWCNTs) in experimental animals, concentrating on MWNT-7, a straight fibrous MWCNT. METHODS:MWCNTs were administered to mice and rats by intraperitoneal injection, intrascrotal injection, subcutaneous injection, intratracheal instilla...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.17-0102-RA
更新日期:2018-01-25 00:00:00
abstract:OBJECTIVES:Although well-being at work is important for occupational health, multi-dimensional workplace well-being measures do not exist for Japanese workers. The purpose of this study was to investigate the validity of the Japanese version of the Workplace PERMA-Profiler. METHODS:Japanese workers completed online su...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2018-0050-OA
更新日期:2018-09-26 00:00:00
abstract::Although the main hazard in cement processing is dust and respiratory tract disorders are the most important group of occupational diseases in this industry, evidence for associations between exposure to cement dust and either respiratory symptoms or functional impairment has not been conclusive. This study was, there...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.49.273
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To investigate associations of work-related stressors and their changes over time with the risk of developing metabolic syndrome (MetS) among Japanese manufacturing workers. METHODS:Participants were 1,040 employees aged 19 to 68 years who were free from MetS at baseline and completed the three year-interval...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2017-0298-OA
更新日期:2018-11-27 00:00:00
abstract:OBJECTIVES:Long working hours may impact human health. In Japan, teachers tend to work long hours. From 2002 to 2012, the number of leaves of absence due to diseases other than mental disorders, or mental disorders among public school teachers increased by 1.3 times (from 2,616 to 3,381), or 1.8 times (from 2,687 to 4,...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.15-0053-OA
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:This study aimed to investigate the association between occupational clusters and allergic rhinitis (AR). METHODS:The study was based on data from the Korean National Health and Nutrition Examination Survey (KNHANES: 2007-2015). This study included 46,965 individuals: 20,491 men and 26,474 women. AR was def...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.2017-0234-OA
更新日期:2018-07-25 00:00:00
abstract::This study was aimed at understanding the relationship among menstrual pattern, dysmenorrhea, life style and working conditions in nurses. The nurses were randomly selected from a medical center in Northern Taiwan. Each subject completed daily records including life and working conditions during the study period. The ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.47.149
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVES:In this study, we focused on the qualitative and quantitative differences of the lung lesions induced by single or multiple intratracheal administration of nickel oxide nanoparticles (NiO). METHODS:Male rats were randomized into groups receiving intratracheal administrations in a single dose or two to four ...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.16-0184-OA
更新日期:2017-03-28 00:00:00
abstract:OBJECTIVES:The aim of this review was to summarize the lessons learned from the experience in protecting the health of workers engaged in operations following the accident at the Fukushima Daiichi Nuclear Power Plant (NPP). METHODS:We reviewed all types of scientific papers examining workers' health found in Medline a...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.15-0084-RA
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Healthcare workers are at high risk of infection from blood-borne pathogens, such as Hepatitis B and C Virus, and Human Immunodeficiency. Occupational exposure to needle-stick injuries (NSIs) continue to have a major health problem in the healthcare systems of developing countries. Thus, this review article ...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1002/1348-9585.12179
更新日期:2020-01-01 00:00:00
abstract::Many dental health workers suffer from musculoskeletal disorders in the upper extremities. In addition to ergonomic factors, psychosocial work characteristics have been linked to musculoskeletal disorders. The present cross-sectional study aimed at investigating how musculoskeletal disorders in the upper extremities (...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.48.192
更新日期:2006-05-01 00:00:00
abstract::Slovenia is a small, fast developing country in the EU with approximately 2,000,000 inhabitants and 700,000 employed. Occupational medicine has been present in Slovenia for as long as 500 yr. Today, 130 specialists of occupational medicine are in charge of health protection of the employed (including transport workers...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.47.193
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:Many kinds of heavy metals are used in industry; thus, it is important for us to clarify their toxicity. For example, lead, which is a component of solder, is notorious for its neurotoxicity, and substitute materials have been sought for many years. Therefore, we examined the genotoxicity of lead and also th...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.l9080
更新日期:2009-01-01 00:00:00
abstract::This study assessed the relationship of age, poor perception of working condition, poor safety environment, poor management and supervision, risk-taking behavior, emotional instability, negative job involvement, job dissatisfaction, job stress, and poor safety performance of workers to occupational injuries. This case...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.46.470
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:Professional drivers are exposed to diesel engine exhaust and outdoor air pollution while driving. Diesel engine exhaust and outdoor air pollution are known carcinogens causing lung cancer. However, previous epidemiological studies examining lung cancer risk in professional drivers have not shown a consisten...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.14-0222-OA
更新日期:2015-01-01 00:00:00
abstract::With the immense economic growth and social development, China has gained worldwide attention. With the quick growth of industrialization, several international professionals are gaining interest in occupational management system and in the role of the Chinese Government in protecting the worker's health. The Law on P...
journal_title:Journal of occupational health
pub_type: 杂志文章,评审
doi:10.1539/joh.17-0229-RA
更新日期:2018-03-27 00:00:00
abstract:OBJECTIVES:Despite the great impact the migration has had in economic, social and health-related fields, and the repercussions of alcohol consumption on them, few data exist concerning the extent of alcohol consumption in migrant workers. The aims of this study were to identify workers with a hazardous drinking problem...
journal_title:Journal of occupational health
pub_type: 杂志文章
doi:10.1539/joh.13-0119-oa
更新日期:2014-01-01 00:00:00