The burden of hospitalisations for community-acquired pneumonia (CAP) and pneumococcal pneumonia in adults in Spain (2003-2007).

abstract：:Six adjuvant formulations were compared for their ability to potentiate the primary and memory antibody responses in mice to three companion animal vaccine immunogens--feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and a recombinantly-derived heartworm antigen. The combination of a novel bacterial ...

journal_title：Vaccine

authors： Usinger WR

更新日期：1997-12-01 00:00:00

abstract：:Cytomegalovirus (CMV) and non-replicating adenoviral vectors can induce expanded, sustained effector-memory CD8+ T-cell responses, termed "memory inflation". During murine CMV (MCMV) infection, CD4+ Tcells maintain inflationary virus-specific CD8+ T-cell responses via IL-2 but not IL-21. Adenovirus vector vaccination ...

journal_title：Vaccine

authors： Gordon CL,Hutchings CL,Highton AJ,Colston JM,Provine NM,Klenerman P

更新日期：2018-11-12 00:00:00

abstract：:Understanding the requirements for protection against pneumococcal carriage and pneumonia will greatly benefit efforts in controlling these diseases. Several antigens, in addition to the polysaccharide capsule, have been implicated in both the virulence and protective immunity against Streptococcus pneumoniae; one of ...

journal_title：Vaccine

authors： Singh R,Singh S,Briles DE,Taub DD,Hollingshead SK,Lillard JW Jr

更新日期：2012-02-01 00:00:00

abstract：:Neuromuscular diseases (NMDs) encompass a broad spectrum of conditions. Because infections may be relevant to the final prognosis of most NMDs, vaccination appears to be the simplest and most effective solution for protecting NMD patients from vaccine-preventable infections. However, very few studies have evaluated th...

journal_title：Vaccine

authors： Esposito S,Bruno C,Berardinelli A,Filosto M,Mongini T,Morandi L,Musumeci O,Pegoraro E,Siciliano G,Tonin P,Marrosu G,Minetti C,Servida M,Fiorillo C,Conforti G,Scapolan S,Ansaldi F,Vianello A,Castaldi S,Principi N,T

更新日期：2014-10-14 00:00:00

abstract：:Experimental whole-parasite immunization through concurrent administration of infectious Plasmodium sporozoites with drugs that prevent pathogenic blood-stage infection represents the current benchmark in malaria vaccine development. Key questions concerning translation remain, including the requirement for single-dos...

journal_title：Vaccine

authors： Pfeil J,Sepp KJ,Heiss K,Meister M,Mueller AK,Borrmann S

更新日期：2014-10-14 00:00:00

abstract：:Mucosal adjuvants are important to overcome the state of immune tolerance normally associated with mucosal delivery and to enhance adaptive immunity to often-weakly immunogenic subunit vaccine antigens. Unfortunately, adverse side effects of many experimental adjuvants limit the number of adjuvants approved for vaccin...

journal_title：Vaccine

authors： Hickey DK,Aldwell FE,Beagley KW

更新日期：2009-10-19 00:00:00

abstract：BACKGROUND:As part of a series of feasibility studies following the development of Canadian vaccine barcode standards, we compared barcode scanning with manual methods for entering vaccine data into electronic client immunization records in public health settings. METHODS:Two software vendors incorporated barcode scan...

journal_title：Vaccine

authors： Pereira JA,Quach S,Hamid JS,Quan SD,Diniz AJ,Van Exan R,Malawski J,Finkelstein M,Samanani S,Kwong JC,Public Health Agency of Canada\/Canadian Institutes of Health Research Influenza Research Network (PCIRN) Program Delivery and Evalu

更新日期：2014-05-13 00:00:00

abstract：BACKGROUND:Vaccination coverage is the usual metrics to evaluate the immunization programs performance. For the 10-valent pneumococcal conjugate (PCV10) vaccine, measuring the delay of vaccination is also important, particularly as younger children are at increased risk of disease. Routinely collected administrative da...

journal_title：Vaccine

authors： Sartori AL,Minamisava R,Afonso ET,Policena GM,Pessoni GC,Bierrenbach AL,Andrade AL

更新日期：2017-02-15 00:00:00

abstract：:We have shown previously that expression library immunization is viable alternative approach to induce protective immunity against Neisseria meningitidis serogroup B. In this study we report that few rounds of library screening allow identification of protective pools of defined antigens. A previously reported protect...

journal_title：Vaccine

authors： Yero D,Pajón R,Pérez Y,Fariñas M,Cobas K,Diaz D,Solis RL,Acosta A,Brookes C,Taylor S,Gorringe A

更新日期：2007-07-09 00:00:00

abstract：AIMS:The study was designed to evaluate a novel cationic lipid DNA adjuvant (N3) and its function for HIV-1gp160/rev DNA plasmid delivered intranasally. The primary N3/HIV-DNA plasmid immunizations were boosted intranasally with a gp41 peptide in a anionic L3 adjuvant. This novel prime-boost strategy of mucosal immuniz...

journal_title：Vaccine

authors： Hinkula J,Devito C,Zuber B,Benthin R,Ferreira D,Wahren B,Schröder U

更新日期：2006-05-22 00:00:00

abstract：:An ELISA-immunocapture assay was developed for quantification of influenza neuraminidases (N2 and B), with a sensitivity about 10 ng neuramidase(NA)/ml. This sensitive and specific assay was applied to several trivalent vaccine preparations (1997/1998 and 1998/1999). It was shown capable to detect 3.5-6.9 microg NA/ml...

journal_title：Vaccine

authors： Aymard M

更新日期：2002-05-15 00:00:00

abstract：:This randomized, double-blind trial conducted in the US and Canada was conducted to compare the safety and immunogenicity of two dosages of live attenuated oral monovalent G1 human rotavirus (HRV) vaccine administered orally at a 2-month interval concomitantly with routine childhood vaccines to healthy infants 5-15 we...

journal_title：Vaccine

authors： Dennehy PH,North American Human Rotavirus Vaccine Study Group.

更新日期：2006-05-01 00:00:00

abstract：:The aim of this study was to determine the rubella seroprevalence in women of reproductive age. This cross-sectional study was conducted on women aged 15-49 years. Serologic studies were performed by using the ELISA method. The number of women enrolled in the study was 607, the mean age was 30.7+/-9.3 years and 13.2% ...

journal_title：Vaccine

authors： Sasmaz T,Kurt AO,Ozturk C,Bugdayci R,Oner S

更新日期：2007-01-15 00:00:00

abstract：:Interest in addressing antimicrobial resistance (AMR) has grown recently but little effort has been made to consider how existing and new vaccines could impact on AMR. A 2017 Chatham House meeting considered the role of vaccines and how to demonstrate their value through their impact on AMR. Ways existing vaccines hav...

journal_title：Vaccine

authors： Clift C,Salisbury DM

更新日期：2017-12-04 00:00:00

abstract：:Gavi, the Vaccine Alliance, supports immunisation programmes in eligible countries to reach children with lifesaving vaccines. Dramatic improvement in the scale and performance of current cold chain systems is required to extend the reach of immunisation services - especially for children living in remote locations - ...

journal_title：Vaccine

authors： Azimi T,Franzel L,Probst N

更新日期：2017-04-19 00:00:00

abstract：:Praziquantel (PZQ), which is used to treat all forms of schistosomiasis, has been shown to induce strong T cell activities and decrease T regulatory cell levels. In our study, we investigated whether PZQ may be used as an adjuvant for a hepatitis B surface antigen (HBsAg) DNA vaccine (pcD-S2) in eliciting strong humor...

journal_title：Vaccine

authors： Zou Q,Zhong Y,Su H,Kang Y,Jin J,Liu Q,Geng S,Zhao G,Wang B

更新日期：2010-02-23 00:00:00

abstract：:In order to provide an estimation of the direct and indirect benefits of pneumococcal vaccination with three protein-conjugate pneumococcal vaccines (PCV) we described the epidemiology and mortality from invasive pneumococcal disease (IPD) in Denmark between 2000 and 2005. Approximately 1080 cases were registered annu...

journal_title：Vaccine

authors： Harboe ZB,Valentiner-Branth P,Benfield TL,Christensen JJ,Hjuler T,Kaltoft M,Krogfelt KA,Lambertsen L,Konradsen HB

更新日期：2008-07-04 00:00:00

abstract：:A number of clinical reports of drug interactions with influenza vaccine have been made. We hypothesized that CYP3A4 activity would decrease following influenza immunization. Fifteen healthy subjects had erythromycin breath tests (ERMBT) and influenza antibody titer hemagglutinin inhibition assay (HIA) before and afte...

journal_title：Vaccine

authors： Hayney MS,Hammes RJ,Fine JP,Bianco JA

更新日期：2001-12-12 00:00:00

abstract：BACKGROUND:Little is known about inactivated influenza vaccine effectiveness (IVE) in preventing very severe disease, including influenza-associated intensive care unit (ICU) admissions. METHODS:The Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance (SHIVERS) project enrolled adults (age...

journal_title：Vaccine

authors： Thompson MG,Pierse N,Sue Huang Q,Prasad N,Duque J,Claire Newbern E,Baker MG,Turner N,McArthur C,SHIVERS investigation team.

更新日期：2018-09-18 00:00:00

abstract：INTRODUCTION:Pregnancy is a risk factor for severe influenza. However, data on influenza incidence during pregnancy are scarce. Likewise, no data are available on influenza vaccine coverage in France since national recommendation in 2012. We aimed to assess these points using a novel nationwide web-based surveillance s...

journal_title：Vaccine

authors： Loubet P,Guerrisi C,Turbelin C,Blondel B,Launay O,Bardou M,Goffinet F,Colizza V,Hanslik T,Kernéis S,GGNET study group.

更新日期：2016-04-29 00:00:00

abstract：:The immunogenicity of 23-valent pneumococcal polysaccharide vaccine was assessed in 57 HIV-1 infected former intravenous drug users and in 20 HIV-1 negative controls. The effect of vaccination on HIV-1 infection was studied in a subgroup of 38 patients, 60% of whom under highly active antiretroviral therapy (HAART). A...

journal_title：Vaccine

authors： Amendola A,Tanzi E,Zappa A,Colzani D,Boschini A,Musher DM,Zanetti AR

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To determine if the addition of a physician peer educator would lead to improved immunization quality when compared to the traditional education provided as part of a vaccines for children (VFC) site visit. METHODS:A randomized controlled trial was conducted. Study participants were private pediatric and fam...

journal_title：Vaccine

authors： Taylor JA,Rietberg K,Greenfield L,Bibus D,Yasuda K,Marcuse EK,Duchin JS

更新日期：2008-08-05 00:00:00

abstract：:The potency of genetic immunization observed in the mouse has demonstrated the utility of DNA vaccines to induce cell-mediated and humoral immune responses. However, it has been relatively difficult to generate comparable responses in non-rodent species. The use of molecular adjuvants may increase the magnitude of the...

journal_title：Vaccine

authors： Maue AC,Waters WR,Palmer MV,Nonnecke BJ,Minion FC,Brown WC,Norimine J,Foote MR,Scherer CF,Estes DM

更新日期：2007-06-11 00:00:00

abstract：:The human adenovirus type 19a/64 (hAd19a) is a rare serotype in the human population that transduces human dendritic cells (DCs) and human muscle cells more efficiently than the well-characterized human adenovirus type 5 (hAd5). To further characterize the potential of this vector as a vaccine we designed replication ...

journal_title：Vaccine

authors： Ragonnaud E,Schroedel S,Mariya S,Iskandriati D,Pamungkas J,Fougeroux C,Daradoumis J,Thomsen AR,Neukirch L,Ruzsics Z,Salomon M,Thirion C,Holst PJ

更新日期：2018-10-01 00:00:00

abstract：:In Autumn 1990, trivalent split influenza virus vaccine containing A/Taiwan/1/86(H1N1) was used to immunize healthy female employees (n = 104). The 11-12 amino acid differences in the HA1 domain of virus haemagglutinin between A/Taiwan/1/86 and representative epidemic H1N1 strains in Finland in 1991 did not result in ...

journal_title：Vaccine

authors： Pyhälä R,Kinnunen L,Kumpulainen V,Ikonen N,Kleemola M,Cantell K

更新日期：1993-01-01 00:00:00

abstract：:Whole-cell vaccines successfully reduce signs of clinical disease and fecal shedding of Mycobacterium avium subsp. paratuberculosis (MAP), however, these vaccines have some limitations. The present study was conducted to identify MAP proteins that might be candidates for the development of an improved vaccine. MAP pro...

journal_title：Vaccine

authors： Stabel JR,Barnhill A,Bannantine JP,Chang YF,Osman MA

更新日期：2012-12-17 00:00:00

abstract：INTRODUCTION:Annual influenza vaccine coverage for young adults (including college students) remains low, despite a 2011 US recommendation for annual immunization of all people 6 months and older. College students are at high risk for influenza morbidity given close living and social spaces and extended travel during s...

journal_title：Vaccine

authors： Bednarczyk RA,Chu SL,Sickler H,Shaw J,Nadeau JA,McNutt LA

更新日期：2015-03-30 00:00:00

abstract：:In an agent-based computer model, we simulate the formation and recall of anti-virus immunological memory. Specifically we try to predict what will happen, both to the response and to memory, when the second infecting virus is partly different from the first one, and when the cross-reactivity of the two branches of th...

journal_title：Vaccine

authors： Cheng Y,Ghersi D,Calcagno C,Selin LK,Puzone R,Celada F

更新日期：2009-02-05 00:00:00

abstract：:Increases in global travel, trade and urbanisation are leading to greater incidence of zoonotic disease, and livestock are often a key link in the spread of disease to humans. As such, livestock vaccination strategies, as a part of broader biosecurity solutions, are critical to both animal and human health. Importantl...

journal_title：Vaccine

authors： Layton DS,Choudhary A,Bean AGD

更新日期：2017-10-20 00:00:00

abstract：:In line with WHO objectives, the Lao Government is committed to eliminate measles by 2012. Yet from 1992 to 2007, the annual incidence of measles remained high while the vaccination coverage showed a wide diversity across provinces. A descriptive study was performed to determine factors affecting compliance with vacci...

journal_title：Vaccine

authors： Phimmasane M,Douangmala S,Koffi P,Reinharz D,Buisson Y

更新日期：2010-09-24 00:00:00