Mucosal co-immunization of mice with recombinant lactococci secreting VapA antigen and leptin elicits a protective immune response against Rhodococcus equi infection.

abstract：:Topological and stereo-electron characteristics are essential in major histocompability class II-peptide-T-cell receptor (MHC-p-TCR) complex formation for inducing an appropriate immune response. Modified high activity binding peptides (mHABPs) were synthesised for complete full protection antimalarial vaccine develop...

journal_title：Vaccine

authors： Bermúdez A,Calderon D,Moreno-Vranich A,Almonacid H,Patarroyo MA,Poloche A,Patarroyo ME

更新日期：2014-04-11 00:00:00

abstract：:Porcine circovirus type 2 (PCV2) is an economically important swine pathogen and vaccination is the primary tool for the disease control. Previously, we developed a more cost-effective PCV2 virus-like particle (VLP) vaccine by using ELPylation technology. In the present study, we compared the ELPylated VLP (ELP-VLP) P...

journal_title：Vaccine

authors： Li Y,Lin Y,Xin G,Zhou X,Lu H,Zhang X,Xia X,Sun H

更新日期：2020-05-13 00:00:00

abstract：:Vaccination of health-care workers (HCWs) against seasonal influenza has been consistently recommended worldwide in order to prevent nosocomial transmission and ensure delivery of health-care services during outbreaks. We describe the effects of a nationwide campaign to promote influenza vaccination among HCWs working...

journal_title：Vaccine

authors： Dedoukou X,Nikolopoulos G,Maragos A,Giannoulidou S,Maltezou HC

更新日期：2010-08-23 00:00:00

abstract：:We aimed to evaluate the present situation and possible risk factors of HBV transmission after the implementation of the routine immunization among children exposed to HBV infected mothers in a developing area in northwest China. Two hundred and twenty one HBsAg carrier mothers and 247 children born to them were final...

journal_title：Vaccine

authors： Li F,Wang Q,Zhang L,Su H,Zhang J,Wang T,Huang D,Wu J,Yan Y,Fan D

更新日期：2012-11-19 00:00:00

abstract：:Peripheral blood mononuclear cells (PBMCs) from unvaccinated and vaccinated bovine calves were employed to study the alteration of different T-cell subpopulations, functional competence and detection of foot-and-mouth disease virus (FMDV) at different hours post in vitro infection (hpi) with FMDV serotype either O or ...

journal_title：Vaccine

authors： Joshi G,Sharma R,Kakker NK

更新日期：2009-11-12 00:00:00

abstract：:During their sixth annual meeting held in Manila (Philippines), the Asian Rabies Expert Bureau (AREB) reviewed the implementation of programs for rabies prevention, control, and elimination in Asia. AREB members strongly support a "one health" approach for controlling rabies, combining increased public awareness, comm...

journal_title：Vaccine

authors： Dodet B,Asian Rabies Expert Bureau (AREB).

更新日期：2010-04-26 00:00:00

abstract：:In response to global interest in the development of a universal influenza vaccine, the Bill & Melinda Gates Foundation, PATH, and the Global Funders Consortium for Universal Influenza Vaccine Development convened a meeting of experts (London, UK, May 2018) to assess the role of a standardized controlled human influen...

journal_title：Vaccine

authors： Innis BL,Scorza FB,Blum JS,Jain VK,Aguilar AO,Post DJ,Roberts PC,Wairagkar N,White J,Bresee J

更新日期：2019-08-14 00:00:00

abstract：INTRODUCTION:During the 2018-2019 influenza season, vaccination coverage among U.S. children was 62.6%. The purpose of this study was to estimate the prevalence of influenza vaccinations among pediatric patients seen in U.S. health centers, and to explore potential disparities in vaccination coverage among subpopulatio...

journal_title：Vaccine

authors： Lebrun-Harris LA,Mendel Van Alstyne JA,Sripipatana A

更新日期：2020-09-03 00:00:00

abstract：:We describe here the preclinical development of a dengue vaccine composed of recombinant subunit carboxy-truncated envelope (E) proteins (DEN-80E) for each of the four dengue serotypes. Immunogenicity and protective efficacy studies in Rhesus monkeys were conducted to evaluate monovalent and tetravalent DEN-80E vaccin...

journal_title：Vaccine

authors： Govindarajan D,Meschino S,Guan L,Clements DE,ter Meulen JH,Casimiro DR,Coller BA,Bett AJ

更新日期：2015-08-07 00:00:00

abstract：:Two live recombinant vaccines (Flc9 and Flc11) against classical swine fever (CSF) were evaluated for their capacity to reduce transmission of virulent CSF virus (CSFV) among vaccinated pigs. In Flc9 the 5' terminal half of the E2 gene of the C-strain, a CSFV vaccine strain, was exchanged with the homologous gene of t...

journal_title：Vaccine

authors： de Smit AJ,Bouma A,van Gennip HG,de Kluijver EP,Moormann RJ

更新日期：2001-01-08 00:00:00

abstract：BACKGROUND:The study was designed to determine the feasibility of implementing routine dTpa vaccination in the maternity ward to new mothers and to assess midwives' attitudes toward pertussis booster vaccination, their perceived susceptibility and severity of pertussis in their patients' communities, the perceived barr...

journal_title：Vaccine

authors： Robbins SC,Leask J,Hayles EH,Sinn JK

更新日期：2011-08-05 00:00:00

abstract：:We report the results of the handsearch of all the issues of Vaccine from 1983 to 1994 to identify randomized and controlled clinical trials (RCTs and CCTs) with the aim of setting up a Cochrane data base of vaccine trials. We read 1119 original papers and located 231 trials of which 117 (50.6%) were RCTs and 114 (49....

journal_title：Vaccine

authors： Jefferson T,Jefferson V

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:PCV13 (conjugated polysaccharide) and PPSV23 (polysaccharide only) are two licensed vaccines targeting S. pneumoniae. The role of CD4 T-cell responses in pneumococcal vaccines among healthy participants and their impact on antibodies is not yet known. METHODS:Ten adults (5 old and 5 young) received PCV13 (p...

journal_title：Vaccine

authors： Sterrett S,Peng BJ,Burton RL,LaFon DC,Westfall AO,Singh S,Pride M,Anderson AS,Ippolito GC,Schroeder HW Jr,Nahm MH,Krishna Prasad A,Goepfert P,Bansal A

更新日期：2020-02-11 00:00:00

abstract：BACKGROUND:During the past decade, in the United States, an increasing number of hepatitis B outbreaks have been reported in assisted living facilities (ALFs) as a result of breaches in infection control practices. We evaluated the seroprotection rates conferred by hepatitis B vaccine among older adults during a respon...

journal_title：Vaccine

authors： Tohme RA,Awosika-Olumo D,Nielsen C,Khuwaja S,Scott J,Xing J,Drobeniuc J,Hu DJ,Turner C,Wafeeg T,Sharapov U,Spradling PR

更新日期：2011-11-21 00:00:00

abstract：BACKGROUND:Timely vaccine supply is critical during influenza pandemics. A recombinant hemagglutinin (rHA)-based vaccine could overcome production hurdles of egg-based vaccines but has never previously been tested in a real-life pandemic setting. The primary aim was to determine the efficacy of a recombinant pandemic v...

journal_title：Vaccine

authors： Gordon DL,Sajkov D,Woodman RJ,Honda-Okubo Y,Cox MM,Heinzel S,Petrovsky N

更新日期：2012-08-03 00:00:00

abstract：:Dynamic studies of influenza virus infection in the live cells are limited because of the lack of appropriate methods for non-invasive detection of the viral components. Using the split-GFP strategy, we have recently developed and characterized an unimpaired recombinant influenza A virus encoding a tagged PB2 subunit ...

journal_title：Vaccine

authors： Avilov SV,Moisy D,Naffakh N,Cusack S

更新日期：2012-12-07 00:00:00

abstract：BACKGROUND:In France, midwives have recently been authorized to administer various vaccines to women (including pregnant women), newborns, and their family members. This is expected to enhance vaccine coverage. However, the French high level of vaccine hesitancy is also observed in some healthcare workers. We thus aime...

journal_title：Vaccine

authors： Massot E,Epaulard O

更新日期：2018-08-16 00:00:00

abstract：:To facilitate site-directed chemical coupling of antigens to the heat labile enterotoxin B subunit of Escherichia coli (LTB), a series of genetically modified fusion proteins of LTB were constructed. The LTB fusion proteins had modified versions of a short (14 amino acid) spacer epitope called the Pk tag attached at t...

journal_title：Vaccine

authors： O'Dowd AM,Botting CH,Precious B,Shawcross R,Randall RE

更新日期：1999-03-17 00:00:00

abstract：:To study the regulation of the human immune response to hepatitis B surface antigen (HBsAg) we have carefully monitored the in vivo humoral and in vitro cellular immune responses to HBsAg in 50 subjects receiving four doses of hepatitis B vaccine according to a 0, 1, 2, 12 month vaccination scheme. Twenty-three subjec...

journal_title：Vaccine

authors： Leroux-Roels G,Van Hecke E,Michielsen W,Voet P,Hauser P,Pêtre J

更新日期：1994-07-01 00:00:00

abstract：:In Portugal, the 7-valent pneumococcal conjugate vaccine (PCV7) was not introduced in the national immunization plan but was commercially available between 2001 and 2010. We studied serotype distribution and antibiotic susceptibility of Streptococcus pneumoniae carried by children in 2009 and 2010. Vaccination with PC...

journal_title：Vaccine

authors： Nunes S,Félix S,Valente C,Simões AS,Tavares DA,Almeida ST,Paulo AC,Brito-Avô A,de Lencastre H,Sá-Leão R

更新日期：2016-03-29 00:00:00

abstract：:The antimetastatic effects of MDP-Lys(L18), a lipophilic derivative of muramyl dipeptide (MDP), against three different types of highly metastatic murine tumour cells, B16-BL6 melanoma, colon 26-M3.1 carcinoma and L5178Y-ML25 T lymphoma, were examined in C57BL/6, Balb/c and CDF1 mice, respectively. The administration ...

journal_title：Vaccine

authors： Yoo YC,Saiki I,Sato K,Azuma I

更新日期：1994-02-01 00:00:00

abstract：:This randomized, double-blind trial conducted in the US and Canada was conducted to compare the safety and immunogenicity of two dosages of live attenuated oral monovalent G1 human rotavirus (HRV) vaccine administered orally at a 2-month interval concomitantly with routine childhood vaccines to healthy infants 5-15 we...

journal_title：Vaccine

authors： Dennehy PH,North American Human Rotavirus Vaccine Study Group.

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:Persistent hepatitis B virus (HBV) infection is a major cause of morbidity and mortality in sub-Saharan Africa. The HIV epidemic has the potential to affect its biology. Immunisation protocols established in the pre-HIV era are based upon data showing predominantly horizontal infant transmission. This study ...

journal_title：Vaccine

authors： Andersson MI,Maponga TG,Ijaz S,Barnes J,Theron GB,Meredith SA,Preiser W,Tedder RS

更新日期：2013-11-12 00:00:00

abstract：:The field of vaccinology is increasingly moving toward the generation, analysis, and modeling of extremely large and complex high-dimensional datasets. We have used data such as these in the development and advancement of the field of vaccinomics to enable prediction of vaccine responses and to develop new vaccine can...

journal_title：Vaccine

authors： Oberg AL,McKinney BA,Schaid DJ,Pankratz VS,Kennedy RB,Poland GA

更新日期：2015-09-29 00:00:00

abstract：:In this work, we explored the potential of cationic solid lipid nanoparticles (cSLN) as efficient adjuvants for inactivated foot and mouth disease virus (iFMDV) vaccine. The cSLN were prepared by O/W emulsion method with Compritol 888 ATO as lipid matrix, and were modified by cationic lipid Didodecyldimethylammonium b...

journal_title：Vaccine

authors： Li S,Yang Y,Lin X,Li Z,Ma G,Su Z,Zhang S

更新日期：2020-03-04 00:00:00

abstract：:Hepatitis E virus (HEV) is a major cause of enterically transmitted acute hepatitis of adults in developing nations. Our present studies show that, the complete ORF2 gene (1-660 amino acids, a.a.) coding for capsid protein of HEV as candidate DNA vaccine induced significant specific humoral and cellular immune respons...

journal_title：Vaccine

authors： Deshmukh TM,Lole KS,Tripathy AS,Arankalle VA

更新日期：2007-05-30 00:00:00

abstract：:A randomized, double-blind, controlled clinical trial was conducted to evaluate the efficacy and safety of CJ-50300, a newly developed cell culture-derived smallpox vaccine, and to determine its minimum effective dose. The overall rates of cutaneous "take" reaction and humoral and cellular immunogenicity in CJ-50300 v...

journal_title：Vaccine

authors： Jang HC,Kim CJ,Kim KH,Lee KH,Byun YH,Seong BL,Saletti G,Czerkinsky C,Park WB,Park SW,Kim HB,Kim NJ,Oh MD

更新日期：2010-08-16 00:00:00

abstract：:Rhesus-human rotavirus reassortants incorporating the gene expressing the VP7 surface protein of human rotavirus serotypes 1 or 2, and the remaining ten genes from rhesus rotavirus (RRV) were evaluated as candidate oral vaccines in 2-4-month-old infants. A single dose of the serotype 1 reassortant vaccine which had a ...

journal_title：Vaccine

authors： Vesikari T,Varis T,Green K,Flores J,Kapikian AZ

更新日期：1991-05-01 00:00:00

abstract：:Tattooing has been shown to be very efficient at inducing immunity by vaccination with DNA vaccines. In this study, we examined the usability of tattooing for delivery of peptide vaccines. We compared tattooing with subcutaneous (s.c.) needle injection using peptides derived from human papillomavirus type 16 (HPV16) p...

journal_title：Vaccine

authors： Pokorná D,Poláková I,Kindlová M,Dusková M,Ludvíková V,Gabriel P,Kutinová L,Müller M,Smahel M

更新日期：2009-06-02 00:00:00

abstract：:Hepatitis B infections are responsible for more than 300 thousand deaths per year in the Western Pacific Region. Because of this high burden, the countries and areas of the Region established a goal of reducing hepatitis B chronic infection prevalence among children to less than 1% by 2017. This study was conducted to...

journal_title：Vaccine

authors： Wiesen E,Diorditsa S,Li X

更新日期：2016-05-27 00:00:00