Adjunctive pharmacologic therapy in percutaneous coronary intervention: part I antiplatelet therapy.

Abstract:

:Ischemic heart disease is a major cause of morbidity and mortality throughout the world. Percutaneous coronary intervention (PCI) has rapidly evolved from balloon angioplasty to drug-eluting stents over the past 25 years and has become an important treatment option for coronary heart disease. During PCI, atherosclerotic plaque disruption and the endothelium denudation stimulate both platelet aggregation and the thrombus generation. Therefore, pharmacological adjuvant therapies to protect the procedure-related thrombotic complication during PCI are indispensable. In addition to aspirin, whose benefit has been clearly shown in ischemic heart disease, clopidogrel and prasugrel have shown to dramatically reduce the rate of thrombosis after stent placement. The introduction of glycoprotein IIb/IIIa inhibitors has further improved the results of PCI especially in high-risk patients. In addition, several new drugs with antiplatelet or with antithrombin activities are currently under development.

journal_name

Coron Artery Dis

journal_title

Coronary artery disease

authors

Kim SJ,Giugliano RP,Jang IK

doi

10.1097/MCA.0b013e32833729e3

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

100-12

issue

1

eissn

0954-6928

issn

1473-5830

journal_volume

22

pub_type

杂志文章,评审
  • Serum levels of YKL-40 increases in patients with acute myocardial infarction.

    abstract:OBJECTIVES:YKL-40 is secreted by macrophages, including those in atherosclerotic plaques, neutrophils, and vascular smooth muscle cells. Circulating YKL-40 is elevated in patients with inflammation and increased tissue remodeling. The aim was to examine the sequential changes in serum YKL-40 in patients with acute myoc...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0b013e3282f40dd5

    authors: Nøjgaard C,Høst NB,Christensen IJ,Poulsen SH,Egstrup K,Price PA,Johansen JS

    更新日期:2008-06-01 00:00:00

  • Cardiac rotation and relaxation after anterolateral myocardial infarction.

    abstract:BACKGROUND:Both systolic and diastolic dysfunction have been observed in patients with anterolateral myocardial infarction. Diastolic dysfunction is related to disturbances in relaxation and diastolic filling. OBJECTIVE:To analyse cardiac rotation, regional shortening and diastolic relaxation in patients with anterola...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-200005000-00009

    authors: Nagel E,Stuber M,Lakatos M,Scheidegger MB,Boesiger P,Hess OM

    更新日期:2000-05-01 00:00:00

  • Association of lymphocyte-to-monocyte ratio with total coronary plaque burden in patients with coronary artery disease.

    abstract:BACKGROUND:Lymphocyte-to-monocyte ratio (LMR) is involved in all stages of coronary atherosclerosis and related to coronary artery disease (CAD). However, the correlation between LMR and the coronary plaque burden of CAD is not clearly elucidated. Therefore, this study aimed to investigate their correlation in patients...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0000000000000857

    authors: Si Y,Liu J,Shan W,Zhang Y,Han C,Wang R,Sun L

    更新日期:2020-11-01 00:00:00

  • The relative rapidity of recanalization induced by recombinant tissue-type plasminogen activator (r-tPA) and TNK-tPA, assessed with enzymatic methods.

    abstract:BACKGROUND:Comparison of different plasminogen activators is difficult because conventional endpoints such as mortality are relatively insensitive to potential differences in efficacy with respect to rapidity of recanalization of infarct-related arteries. METHODS:This study was performed to determine whether valid com...

    journal_title:Coronary artery disease

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/00019501-200007000-00008

    authors: Binbrek A,Rao N,Absher PM,Van de Werf F,Sobel BE

    更新日期:2000-07-01 00:00:00

  • Sequelae of spinal cord stimulation for refractory angina pectoris. Reliability and safety profile of long-term clinical application.

    abstract:BACKGROUND:Spinal cord stimulation (SCS) is effective in the treatment of severe coronary artery disease (CAD) unresponsive to anti-anginal medication or revascularization procedures. However, there is still concern about its safety. OBJECTIVE:To investigate the reliability, morbidity, and mortality aspects of SCS in ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-199701000-00005

    authors: Jessurun GA,Ten Vaarwerk IA,DeJongste MJ,Tio RA,Staal MJ

    更新日期:1997-01-01 00:00:00

  • Hospitalisations, infarct development, and mortality in patients with chest pain and a normal admission electrocardiogram in relation to gender.

    abstract:BACKGROUND:The aim of this study was to compare the outcome for men and women with chest pain or other symptoms suggestive of acute myocardial infarction (AMI) and a normal ECG on admission. METHODS:All patients who presented to our emergency room over a 21-month period with chest pain or other symptoms suggestive of ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:

    authors: Karlson BW,Herlitz J

    更新日期:1996-03-01 00:00:00

  • The role of Fas in the progression of ischemic heart failure: prohypertrophy or proapoptosis.

    abstract::During myocardial ischemia, cardiomyocytes can undergo apoptosis or compensatory hypertrophy. Fas expression is upregulated in the myocardial ischemia and is coupled to both apoptosis and hypertrophy of cardiomyocytes. The role of Fas in apoptosis induction or cardiomyocyte hypertrophy during ischemic conditions is, h...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,评审

    doi:10.1097/MCA.0b013e3283093707

    authors: Feng QZ,Zhao YS,Abdelwahid E

    更新日期:2008-11-01 00:00:00

  • Treatment of mild-moderate calcified coronary lesions with sirolimus-eluting stent: real world data from a single center.

    abstract:BACKGROUND:Calcified coronary lesions have commonly been considered as a challenge for interventional cardiologists, and few previous studies of sirolimus-eluting stent (SES) for calcified lesion have been limited by small sample size. Therefore, we evaluated the effectiveness of SES implantation for the treatment of c...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0b013e328330d5ab

    authors: Yuan JQ,Li JJ,Qin XW,Xu B,Yang YJ,Chen JL,Qiao SB,Ma WH,Yao M,Liu HB,Wu YJ,Chen J,You SJ,Dai J,Xia R,Gao RL

    更新日期:2010-01-01 00:00:00

  • The effect of low FT3 levels on coronary artery calcification and MACE in outpatients with suspected coronary artery disease.

    abstract:OBJECTIVE:Considerable evidence suggests that thyroid dysfunction, especially hypothyroidism, may lead to coronary artery disease (CAD). The aim of this study is to investigate the effect of low serum levels of free triiodothyronine (FT3) on coronary artery calcification in outpatients with suspected CAD and the occurr...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0000000000000095

    authors: Zhu L,Gao C,Wang X,Qi D,Zhang Y,Li M,Liu W,Hao P

    更新日期:2014-08-01 00:00:00

  • Modalities to assess myocardial viability in the modern cardiology era.

    abstract::Detection of viable myocardium in patients with left ventricular dysfunction has become an increasingly important guide to prognosis and treatment. This article reviews the current status and future potential for the application of modalities to assess myocardial viability. Imaging and other techniques that are review...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,评审

    doi:10.1097/00019501-200609000-00011

    authors: Hamdan A,Zafrir N,Sagie A,Kornowski R

    更新日期:2006-09-01 00:00:00

  • Comparative effectiveness of different contemporary drug-eluting stents in routine clinical practice: a multigroup propensity score analysis using data from the stent-specific, multicenter, prospective registries.

    abstract:OBJECTIVE:Data on the comparative effectiveness of contemporary drug-eluting stents (DES) in the unrestricted, real-world setting are limited. We investigated the long-term effectiveness and safety of contemporary different drug-eluting stents by means of multiple treatment propensity score weighting. PATIENTS AND MET...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MCA.0000000000000730

    authors: Kwon O,Kang SH,Lee JB,Ahn JM,Lee CH,Kang DY,Lee PH,Kang SJ,Lee SW,Kim YH,Lee CW,Park SW,Park DW,Park SJ,IRIS-DES Registry Investigators.

    更新日期:2019-06-01 00:00:00

  • Tako-tsubo cardiomyopathy and coronary artery disease: a possible association.

    abstract:BACKGROUND:In the medical literature, several cases of Tako-tsubo cardiomyopathy (TTC) with coronary artery disease (CAD) have been reported, and in clinical practice, several typical TTC cases show relevant stenoses of the coronary arteries spatially unrelated to the dysfunctional myocardium. OBJECTIVE:This study aim...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MCA.0b013e3283645c4e

    authors: Parodi G,Citro R,Bellandi B,Del Pace S,Rigo F,Marrani M,Provenza G,Leoncini M,Salerno Uriarte JA,Bovenzi F,Bossone E,Tako-tsubo Italian Network (TIN).

    更新日期:2013-09-01 00:00:00

  • Gliding-window fast Fourier transform analysis of the entire QRS complex and the distribution of area ratio peaks in healthy subjects and patients with myocardial infarction.

    abstract:BACKGROUND:The high-frequency contribution (i.e. 60-120 Hz) within the QRS complex of the surface ECG is supposed to be related to the arrhythmogenic substrate underlying sustained ventricular tachycardia in patients with coronary artery disease. One of the factors that prevents a wider clinical application of spectral...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-199403000-00011

    authors: Slavkovský P,Hulín I

    更新日期:1994-03-01 00:00:00

  • Hemodynamic changes determine the efficacy of thrombolysis: results from an in-vitro flow model.

    abstract:BACKGROUND:The efficacy of thrombolytic therapy might be influenced by changes in the hemodynamic status. The aim of the study was to examine whether changes in perfusion pressure could affect the time to reflow in an in-vitro model. METHODS:The in-vitro flow system comprised flexible plastic tubes that enclosed a blo...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-199809010-00007

    authors: Kornowski R,Mendelevich L,Zaretsky U,Einav S,Laniado S,Keren G

    更新日期:1998-01-01 00:00:00

  • Thyroid hormone and thyroid hormone analogues in the treatment of heart failure.

    abstract::The thyroid hormone analogue DITPA is a promising potential new treatment for heart failure. Although the mechanism of action is incompletely determined, it is clear that DITPA improves systolic as well as diastolic function. It is also clear that the effects of DITPA are intrinsic to the muscle and not the result of ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,评审

    doi:10.1097/00019501-199909000-00008

    authors: Spooner PH,Morkin E,Goldman S

    更新日期:1999-09-01 00:00:00

  • Role of activation-dependent platelet membrane glycoproteins in development of subacute occlusive coronary stent thrombosis.

    abstract:BACKGROUND:Platelets have an important role in coronary thrombosis. METHODS:We studied 151 consecutive patients undergoing implantation of Palmaz-Schatz stents because of suboptimal results after coronary balloon angioplasty treated by intense anticoagulation. Surface exposure of the constitutively expressed glycoprot...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-199703000-00001

    authors: Gawaz M,Neumann FJ,Ott I,May A,Rüdiger S,Schömig A

    更新日期:1997-03-01 00:00:00

  • Diurnal variation of the P-wave dispersion in chronic ischemic heart diseases.

    abstract:OBJECTIVE:Electrocardiographic indices like maximum P-wave duration (P(max)) and P-wave dispersion (PD) can be used to detect patients with atrial conduction disorders, myocardial ischemia and those at risk for atrial fibrillation. Considering the diurnal variation of ischemia in patients with significant coronary lesi...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/01.mca.0000236284.64059.be

    authors: Yíldírím N,Topaloglu S,Bozboga S,Ocal A,Saricam E

    更新日期:2006-12-01 00:00:00

  • The surgical management of congenital coronary artery fistula.

    abstract:BACKGROUND:Congenital coronary artery fistula (CAF) is a very rare cardiovascular anomaly and only 400 cases have been reported. The purpose of this study was to analyse the experience of surgical treatments in CAF and evaluate the surgical indications, techniques and long-term results. METHODS:A retrospective study r...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-199412000-00006

    authors: Chen Y,Belboul A,Roberts D

    更新日期:1994-12-01 00:00:00

  • Plasma homocysteine level and development of coronary artery disease.

    abstract:BACKGROUND:The plasma level of homocysteine is an independent risk factor for atherosclerotic vascular disease. The relationship between plasma homocysteine level and the onset of coronary artery disease (CAD) has not been established. OBJECTIVE:To investigate the relationship between plasma homocysteine level and the...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-199910000-00002

    authors: Kawashiri M,Kajinami K,Nohara A,Yagi K,Inazu A,Koizumi J,Haraki T,Takegoshi T,Mabuchi H

    更新日期:1999-10-01 00:00:00

  • Comparison of peripheral arterial tonometry and flow-mediated vasodilation for assessment of the severity and complexity of coronary artery disease.

    abstract:OBJECTIVE:Noninvasive flow-mediated vasodilation (FMD) is a widely used method to assess endothelial function, but its technical difficulty and problems remain obstacles for use in clinical practice. Reactive hyperemia-peripheral arterial tonometry (RH-PAT) was developed as a simpler and more reproducible method. We co...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0000000000000094

    authors: Woo JS,Jang WS,Kim HS,Lee JH,Choi EY,Kim JB,Kim WS,Kim KS,Kim W

    更新日期:2014-08-01 00:00:00

  • Low-pressure deployment of stents: short- and long-term outcome.

    abstract::This study investigates a strategy of low-pressure stenting with concomitant anti-platelet treatment designed to prevent short- and long-term events after stenting. Ninety consecutive patients who underwent percutaneous transluminal coronary angioplasty with stenting using low-pressure stent deployment (mean 8.1 atmos...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-200106000-00007

    authors: Cafri C,Weinstein JM,Gilutz H,Kobal S,Ilia R

    更新日期:2001-06-01 00:00:00

  • Noninvasive assessment of coronary artery ectasia using multidetector computed tomography.

    abstract:OBJECTIVES:The aim of this study is to determine the prevalence of coronary artery ectasia and its relationship to atheromatous changes in participants undergoing coronary computed tomography angiography. BACKGROUND:Coronary artery ectasia occasionally encountered on conventional coronary angiography is considered a m...

    journal_title:Coronary artery disease

    pub_type: 临床试验,杂志文章

    doi:10.1097/MCA.0b013e3280144be1

    authors: Zeina AR,Sharif D,Blinder J,Rosenschein U,Barmeir E

    更新日期:2007-05-01 00:00:00

  • Visual scoring of coronary artery calcification in lung cancer screening computed tomography: association with all-cause and cardiovascular mortality risk.

    abstract:OBJECTIVE:Current and former smokers are at an increased risk for lung cancer and cardiovascular disease (CVD). We investigated two methods of visual scoring of coronary artery calcium on lung cancer screening computed tomography (CT) to predict cardiovascular and all-cause mortality. PARTICIPANTS AND METHODS:Cases we...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0000000000000189

    authors: Watts JR Jr,Sonavane SK,Snell-Bergeon J,Nath H

    更新日期:2015-03-01 00:00:00

  • Effects of different strategies on high thrombus burden in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary catheterization.

    abstract:OBJECTIVE:This study aimed at evaluating efficacy and safety of thrombus aspiration and intracoronary-targeted thrombolysis on coronary thrombus burden in ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous catheterization, comparing their effects on myocardial perfusion through index of...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/MCA.0000000000000743

    authors: Xiao Y,Fu X,Wang Y,Fan Y,Wu Y,Wang W,Zhang Q

    更新日期:2019-12-01 00:00:00

  • Infectious agents in coronary lesions obtained by endatherectomy: pattern of distribution, coinfection, and clinical findings.

    abstract:BACKGROUND:Cytomegalovirus (CMV), Chlamydia pneumoniae (C. pneumoniae), and Helicobacter pylori (H. pylori) have been implicated in atherosclerosis and restenosis after angioplasty. The patterns of distribution within coronary lesions and possible coinfections of these pathogens in the coronary vasculature had not prev...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/00019501-200102000-00001

    authors: Radke PW,Merkelbach-Bruse S,Messmer BJ,vom Dahl J,Dörge H,Naami A,Vogel G,Handt S,Hanrath P

    更新日期:2001-02-01 00:00:00

  • Effects of exercise training on mortality in patients with coronary heart disease.

    abstract::Endothelial dysfunction not only precedes the development of significant coronary artery stenosis, it has also been identified as a general phenomenon predicting future cardiovascular events in patients who are at risk. As regular physical activity as a part of a multifactorial intervention has been shown to affect sy...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,评审

    doi:10.1097/00019501-200605000-00003

    authors: Erbs S,Linke A,Hambrecht R

    更新日期:2006-05-01 00:00:00

  • A randomized comparison of a novel iopromide-based paclitaxel-coated balloon Shenqi versus SeQuent Please for the treatment of in-stent restenosis.

    abstract:BACKGROUND:Treatment of coronary in-stent restenosis (ISR) remains challenging in contemporary clinical applications. Drug-coated balloon (DCB) angioplasty offers an effective treatment for ISR. Shenqi is a novel iopromide-based paclitaxel-coated balloon and its clinical safety, effectiveness and angiographic efficacy ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0000000000000994

    authors: Zhu J,Liu L,Zhu Z,Yang Z,Hu J,Ding F,Zhou Y,Su X,Ge J,Liu X,Tang L,He Y,Zhou G,Ji Z,Li Y,Pang W,Zhang R

    更新日期:2020-11-20 00:00:00

  • The relation between ABO blood types and clinical and platelet function parameters in patients who underwent percutaneous coronary intervention.

    abstract:BACKGROUND:ABO blood groups have been associated with venous thromboembolism and arterial thrombosis. Although platelets play key roles in thrombogenesis, the relation between ABO groups and platelets is not well known and was investigated in this study. PATIENTS AND METHODS:ABO blood type information was retrospectiv...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0000000000000676

    authors: Timur AA,Barnard J,Murugesan G,Gandhi S,Bhatt DL,Kottke-Marchant K

    更新日期:2019-01-01 00:00:00

  • Extracorporeal cardiac shock wave therapy improves left ventricular remodeling after acute myocardial infarction in pigs.

    abstract:OBJECTIVE:We have recently demonstrated that low-energy extracorporeal shock wave therapy improves chronic myocardial ischemia in pigs and humans. In this study, we examined whether our shock wave therapy is also effective at improving left ventricular remodeling after acute myocardial infarction in pigs. METHODS:Acut...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0b013e328089f19b

    authors: Uwatoku T,Ito K,Abe K,Oi K,Hizume T,Sunagawa K,Shimokawa H

    更新日期:2007-08-01 00:00:00

  • Association between serum galectin-3 levels and coronary atherosclerosis and plaque burden/structure in patients with type 2 diabetes mellitus.

    abstract:BACKGROUND:Levels of galectin-3, a member of a family of soluble β-galactoside-binding lectins, are reported to be higher in patients with type 2 diabetes mellitus (DM) and metabolic syndrome. Conflicting results exist on the effects of galectin-3 in diabetic patients. The aim of this study was to investigate the relat...

    journal_title:Coronary artery disease

    pub_type: 杂志文章

    doi:10.1097/MCA.0000000000000252

    authors: Ozturk D,Celik O,Satilmis S,Aslan S,Erturk M,Cakmak HA,Kalkan AK,Ozyilmaz S,Diker V,Gul M

    更新日期:2015-08-01 00:00:00