Abstract：
:The purpose of this research is to develop an algorithm for a feedback controlled local electrical nerve fiber stimulation system which has the purpose to stop the repetitive firing in a particular region of the nervous system. The electrophysiological behavior of the neurons (under electrical currents) is modeled by Hodgkin-Huxley (HH) type nonlinear nerve fiber dynamics. The repetitive firing of in the modeled fiber is due to the deviations in the channel parameters, which is also called as bifurcation in the nonlinear systems theory. A washout filter is augmented to the HH dynamics and then the output of the filter is fed to the external current generator through a linear gain. This gain is computed by linear projective control theory. That is a linear output feedback control technique where the closed loop spectrum of the full state feedback closed loop is partially maintained. By obtaining a spectrum of eigenvalues with completely negative real parts the nerve fibers can be relaxed to the equilibrium point with or without a damped oscillation. The MATLAB script applying the theory of this work is provided at the end of this paper. A MATLAB-Simulink computer simulation is performed in order to verify the algorithm.
journal_name
Comput Methods Programs Biomedjournal_title
Computer methods and programs in biomedicineauthors
Doruk RÖdoi
10.1016/j.cmpb.2010.06.013subject
Has Abstractpub_date
2011-09-01 00:00:00pages
132-44issue
3eissn
0169-2607issn
1872-7565pii
S0169-2607(10)00166-5journal_volume
103pub_type
杂志文章abstract：BACKGROUND AND OBJECTIVE:Gallbladder polyp is a common disease with an overall population prevalence between 4 and 7%. It can be classified as neoplastic and non-neoplastic lesions. Surgical treatment is necessary for neoplastic polyps. Due to its easy accessibility and nonradioactive, ultrasonography is the mostly use...
journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Gene regulatory networks (GRNs) are essential for understanding most molecular processes. In this context, the so-called model-free approaches have an advantage modeling the complex topologies behind these dynamic molecular networks, since most GRNs are difficult to map correctly by any other m...
journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/0169-2607(93)90020-l
更新日期：1993-04-01 00:00:00
abstract：INTRODUCTION:Coronary artery disease (CAD) is still one of the primary causes of death in the developed countries. Stress single-photon emission computed tomography is used to evaluate myocardial perfusion and ventricular function in patients with suspected or known CAD. This study sought to test data mining and machin...
journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
doi：10.1016/j.cmpb.2008.04.001
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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更新日期：2012-08-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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更新日期：2016-11-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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doi：10.1016/0169-2607(89)90177-6
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journal_title：Computer methods and programs in biomedicine
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更新日期：2001-09-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：1996-07-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
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更新日期：2014-10-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：2011-08-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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journal_title：Computer methods and programs in biomedicine
pub_type： 杂志文章
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更新日期：1989-10-01 00:00:00
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journal_title：Computer methods and programs in biomedicine
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更新日期：1986-12-01 00:00:00
