Abstract：
OBJECTIVE:Coronary angiography using multidetector computed tomography (MDCT) allows non-invasive assessment of non-calcified, calcified and mixed plaques. Progression of coronary plaques may be influenced by statins. METHODS:Sixty-three consecutive patients underwent MDCT as a follow-up to their original CT angiography in a retrospective longitudinal study. MDCT was performed by using a voxel size of 0.5 × 0.35 × 0.35 mm(3) at two time points 25 ± 3 months apart. Non-calcified, calcified and mixed coronary plaque components were analysed by using volumetric measurement. The influence of statin, low-density lipoprotein (LDL) and risk factors was assessed by using a linear random intercept model for plaque growth. RESULTS:The volumes of non-calcified, calcified and mixed coronary plaques significantly (P < 0.001) increased from baseline (medians/interquartile ranges = 21/15-39, 7/3-20 and 36/16-69 mm(3)) to follow-up (29/17-44, 13/6-29 and 41/20-75 mm(3)). Statins significantly slowed the growth of non-calcified plaques (statin coefficient β = -0.0036, P = 0.01) but did not significantly affect the growth rate of mixed or calcified plaques. The effect of statin treatment on non-calcified plaques remained significant after adjusting for LDL levels and cardiac risk factors. CONCLUSION:Quantification using MDCT shows that progression of non-calcified coronary plaques may be slowed by statins.
journal_name
Eur Radioljournal_title
European radiologyauthors
Hoffmann H,Frieler K,Schlattmann P,Hamm B,Dewey Mdoi
10.1007/s00330-010-1880-xsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
2824-33issue
12eissn
0938-7994issn
1432-1084journal_volume
20pub_type
临床试验,杂志文章abstract：OBJECTIVES:To investigate the imaging findings and clinical time course of COVID-19 pneumonia. METHODS:A total of 113 baseline and follow-up CT scans from 24 January 2020 to 18 February 2020 were longitudinally collected from 29 confirmed COVID-19 patients in a single center. The changes in the clinical and laboratory...
journal_title：European radiology
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更新日期：2020-11-01 00:00:00
abstract：OBJECTIVES:To investigate the association of contrast-enhanced cone beam breast CT (CE-CBBCT) features, immunohistochemical (IHC) receptors, and molecular subtypes in breast cancer. METHODS:In this retrospective study, patients who underwent preoperative CE-CBBCT and received complete IHC results were analyzed. CE-CBB...
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journal_title：European radiology
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doi：10.1007/s00330-002-1443-x
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abstract：:There is yet no consensus on the application of functional imaging and qualitative image interpretation in the management of gastric cancer. In this second part, we will discuss the role of image-derived quantitative parameters from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and 18F-fluorodeoxygluc...
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pub_type： 杂志文章,评审
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journal_title：European radiology
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abstract：:Psoas abscess is an uncommon condition and, contrary to traditional teaching, tends to be of non-tuberculous aetiology in developed countries. Diagnosis can be delayed since presenting features are non-specific and in many instances misleading, necessitating a high degree of clinical suspicion and early resort to cros...
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journal_title：European radiology
pub_type： 杂志文章,评审
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pub_type： 评论,社论
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pub_type： 杂志文章
doi：10.1007/s00330-010-1745-3
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更新日期：2012-04-01 00:00:00
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更新日期：2019-06-01 00:00:00
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doi：
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abstract：:This study assessed both two-dimensional (2D) TrueFISP imaging for quantifying tongue volume and real-time TrueFISP imaging for evaluating chewing and swallowing in healthy volunteers and patients with acromegaly. In 50 healthy volunteers, tongue volumes were measured using a 2D TrueFISP sequence. Chewing and swallowi...
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