A frequent variant in the ABCA1 gene is associated with increased coronary heart disease risk and a better response to statin treatment in familial hypercholesterolemia patients.

abstract：:The optimal length of clopidogrel therapy in patients with acute coronary syndromes or in those who have undergone percutaneous coronary intervention (PCI) remains controversial. We therefore sought to determine the risk of both perioperative and premature discontinuation of clopidogrel. PubMed and EMBASE databases we...

journal_title：European heart journal

authors： Gaglia MA Jr,Waksman R

更新日期：2011-10-01 00:00:00

abstract：:Hypercholesterolaemia is an important risk factor for cardiovascular disease. Both total and LDL cholesterol levels are three-fold higher at the end of the first year of life and about four-fold higher in adulthood compared with the neonatal period. In the USA, only 25% of infants are exclusively breastfed and simple ...

journal_title：European heart journal

authors： Zubin Maslov P,Hill JA,Lüscher TF,Narula J

更新日期：2020-12-16 00:00:00

abstract：:Haemodynamic effects of pharmacological doses of insulin during acute ischaemic heart failure were studied in 8 dogs. Severe depression of left ventricular function was induced by the injection of 50 micron plastic microspheres into the left main coronary artery. This was demonstrated by a significant increase in left...

journal_title：European heart journal

authors： Reikerås O,Gunnes P,Sørlie D,Ekroth R,Jorde R,Mjøs OD

更新日期：1985-05-01 00:00:00

abstract：:The association between clinical or environmental factors and dilated cardiomyopathy (DCM) has been assessed in a planned case-control study. Patients and controls were men aged between 20 and 65 years, matched for age, profession and geographic location. DCM was defined by strict radiologic and angiographic criteria ...

journal_title：European heart journal

authors： Komajda M,Richard JL,Bouhour JB,Sacrez A,Bourdonnec C,Gerbaux A,Rozensztajn L,Lablanche JM,Matinat D,Morand P

更新日期：1986-06-01 00:00:00

abstract：:The clinical value of QRST isointegral maps (I-maps) for the detection of myocardial infarction (MI) in the presence of left bundle branch block (LBBB) was investigated. We recorded I-maps during sinus rhythm and right ventricular (RV) pacing, which simulated LBBB, in 62 patients with MI (42 patients had at least one ...

journal_title：European heart journal

authors： Suzuki A,Hirai M,Hayashi H,Tomita Y,Ichihara Y,Adachi M,Oguchi S,Takatsu F

更新日期：1993-08-01 00:00:00

abstract：AIM:To determine the frequency of pre-existing valvular disease (VD) among patients with acute coronary syndromes (ACS) and to compare the clinical characteristics, clinical course, treatment, and outcomes of ACS patients with and without pre-existing VD. METHODS AND RESULTS:The Euro Heart Survey ACS prospectively enr...

journal_title：European heart journal

authors： Hasdai D,Lev EI,Behar S,Boyko V,Danchin N,Vahanian A,Battler A

更新日期：2003-04-01 00:00:00

abstract：AIMS:Our objective was to create a simple prognostic risk score for patients with systolic heart failure and mild symptoms. We then assessed the efficacy of eplerenone across different categories of risk. METHODS AND RESULTS:The Eplerenone in Mild Patients Hospitalization and Survival Study in Heart Failure trial (EMP...

journal_title：European heart journal

authors： Collier TJ,Pocock SJ,McMurray JJ,Zannad F,Krum H,van Veldhuisen DJ,Swedberg K,Shi H,Vincent J,Pitt B

更新日期：2013-09-01 00:00:00

abstract：:We examined two 'cohorts' of elderly men, 60 and 67 years old. The two 'cohorts' overlapped to a large extent in terms of numbers but not in the follow-up periods. The mean have been followed-up for 7 and 8 years respectively. Among the 748 60-year-old men without prior myocardial infarction the 7-year incidence of co...

journal_title：European heart journal

authors： Welin L,Eriksson H,Larsson B,Ohlson LO,Svärdsudd K,Tibblin G,Wilhelmsen L

更新日期：1991-06-01 00:00:00

abstract：AIMS:Short QT syndrome (SQTS) is a genetically determined ion-channel disorder, which may cause malignant tachyarrhythmias and sudden cardiac death. Thus far, mutations in five different genes encoding potassium and calcium channel subunits have been reported. We present, for the first time, a novel loss-of-function mu...

journal_title：European heart journal

authors： Templin C,Ghadri JR,Rougier JS,Baumer A,Kaplan V,Albesa M,Sticht H,Rauch A,Puleo C,Hu D,Barajas-Martinez H,Antzelevitch C,Lüscher TF,Abriel H,Duru F

更新日期：2011-05-01 00:00:00

abstract：:The natriuretic peptides are important tools to establish diagnosis and prognosis in heart failure (HF). With application of therapies for HF, changes in both B-type natriuretic peptide (BNP) and its amino terminal cleavage fragment (NT-proBNP) parallel the benefits of the HF therapy applied. This dynamic nature of BN...

journal_title：European heart journal

authors： Troughton R,Michael Felker G,Januzzi JL Jr

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Sixteen cases of sudden unexpected cardiac death, 15 males and one female, are known to have occurred among young Swedish orienteers from 1979 to 1992, of which seven cases occurred between 1989 and 1992. This is considered to be indicative of an increased death rate. RESULTS:Histopathological evaluation sh...

journal_title：European heart journal

authors： Wesslén L,Påhlson C,Lindquist O,Hjelm E,Gnarpe J,Larsson E,Baandrup U,Eriksson L,Fohlman J,Engstrand L,Linglöf T,Nyström-Rosander C,Gnarpe H,Magnius L,Rolf C,Friman G

更新日期：1996-06-01 00:00:00

abstract：:Recombinant tissue-type plasminogen activator (rt-PA) is presently used for the treatment of different clinical entities, mostly myocardial infarction. Its use for treatment of thrombotic dysfunction of prosthetic cardiac valves is more recent and has been only rarely reported. A 33-year-old woman with a St Jude Medic...

journal_title：European heart journal

authors： Prieto Palomino MA,Ruiz de Elvira MJ,Sanchez Llorente F,Torrado E,Castillo JL,Gonzalez de Vega N,Garijo Galve A

更新日期：1989-12-01 00:00:00

abstract：AIMS:Aortic stenosis causes cardiac hypertrophy and fibrosis, which often persists despite pressure unloading after aortic valve replacement. The persistence of myocardial fibrosis in particular leads to impaired cardiac function and increased mortality. We investigated whether granulocyte colony-stimulating factor (G-...

journal_title：European heart journal

authors： Szardien S,Nef HM,Voss S,Troidl C,Liebetrau C,Hoffmann J,Rauch M,Mayer K,Kimmich K,Rolf A,Rixe J,Troidl K,Kojonazarov B,Schermuly RT,Kostin S,Elsässer A,Hamm CW,Möllmann H

更新日期：2012-03-01 00:00:00

abstract：:Twenty-three patients who had undergone aortic valve replacement with a mechanical aortic valve prosthesis (ball-valve: 17, tilting-disc: 6) were investigated by retrograde left ventricular catheterization using a 6 F pigtail catheter. Twelve of these 23 patients also had had combined aortic and mitral valve replaceme...

journal_title：European heart journal

authors： Rigaud M,Dubourg O,Luwaert R,Rocha P,Hamoir V,Bardet J,Bourdarias JP

更新日期：1987-07-01 00:00:00

abstract：AIMS:To assess the outcome and costs of patients with acute myocardial infarction (AMI) after initial admission to hospitals with or without catheterization facilities in Belgium. METHODS AND RESULTS:From a nationwide hospital register, we retrieved the data of 34 961 patients discharged during 1999-2001 with a princi...

journal_title：European heart journal

authors： Van Brabandt H,Camberlin C,Vrijens F,Parmentier Y,Ramaekers D,Bonneux L

更新日期：2006-11-01 00:00:00

abstract：:We found that the incidence and distribution of conduction system disease simultaneously affecting several levels of the system had been incompletely described. We therefore analysed all patients in whom conduction disease had been diagnosed and a complete electrophysiological study of the conduction system had been m...

journal_title：European heart journal

authors： Rasmussen K,Myhre ES,Gunnes P,Wang H

更新日期：1983-02-01 00:00:00

abstract：:Hereditary factors may have a part to play in the development of bicuspid aortic valve. This report concerns a pair of identical twins, probably monozygotic, who required aortic valve replacement as a result of aortic stenosis occurring in bicuspid aortic valves. This supports the contention that there may be a geneti...

journal_title：European heart journal

authors： Godden DJ,Sandhu PS,Kerr F

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Patients with univentricular hearts have decreased exercise tolerance and may demonstrate exertional dyspnoea. It is not known if chronic hypoxaemia exacerbates exercise intolerance and contributes to symptomatic limitation. The extent to which surgical correction of a right-to-left shunt by a Fontan-type pr...

journal_title：European heart journal

authors： Iserin L,Chua TP,Chambers J,Coats AJ,Somerville J

更新日期：1997-08-01 00:00:00

abstract：:The impulses coming from the sinus node synchronically penetrate the AV node via the crista terminalis and inter-atrial septum. Studies in superfused rabbit AV preparations suggest that the crista terminalis is a more effective input than the inter-atrial septum, and that the summation of both inputs facilitates AV no...

journal_title：European heart journal

authors： Sanchis J,Chorro FJ,Such L,Matamoros J,Monmeneu JV,Cortina J,López Merino V

更新日期：1993-10-01 00:00:00

abstract：AIMS:Cardioprotective effects of erythropoietin (EPO) have been shown in experimental and smaller clinical studies. We performed a prospective, multicentre, randomized trial to assess the effects of a single high dose of EPO after primary coronary intervention (PCI) for an ST-elevation myocardial infarction (STEMI). Me...

journal_title：European heart journal

authors： Voors AA,Belonje AM,Zijlstra F,Hillege HL,Anker SD,Slart RH,Tio RA,van 't Hof A,Jukema JW,Peels HO,Henriques JP,Ten Berg JM,Vos J,van Gilst WH,van Veldhuisen DJ,HEBE III Investigators.

更新日期：2010-11-01 00:00:00

abstract：:Ambient air pollution is a leading cause of non-communicable disease globally. The largest proportion of deaths and morbidity due to air pollution is now known to be due to cardiovascular disorders. Several particulate and gaseous air pollutants can trigger acute events (e.g. myocardial infarction, stroke, heart failu...

journal_title：European heart journal

authors： Münzel T,Gori T,Al-Kindi S,Deanfield J,Lelieveld J,Daiber A,Rajagopalan S

更新日期：2018-10-07 00:00:00

abstract：AIMS:To evaluate the accuracy of echocardiography in conjunction with quantitative high-dose dipyridamole technetium-99m sestamibi tomography (SPECT) in detecting coronary allograft vasculopathy. METHODS AND RESULTS:Seventy-eight consecutive heart transplant recipients underwent echocardiography while at rest and high...

journal_title：European heart journal

authors： Ciliberto GR,Ruffini L,Mangiavacchi M,Parolini M,Sara R,Massa D,De Maria R,Gronda E,Vitali E,Parodi O

更新日期：2001-06-01 00:00:00

abstract：:The haemodynamic side-effects of ionic (amidotrizoate) and non-ionic (iopamidol) contrast media after injection into the right atrium were compared in experimental and clinical studies. Pulmonary hypertension was induced in 10 dogs by embolization of the pulmonary vascular bed with agar-agar solution (mean pulmonary a...

journal_title：European heart journal

authors： Schräder R,Hellige G,Kaltenbach M,Kober G

更新日期：1987-12-01 00:00:00

abstract：AIMS:The effect of statins on risk of heart failure (HF) hospitalization and HF death remains uncertain. We aimed to establish whether statins reduce major HF events. METHODS AND RESULTS:We searched Medline, EMBASE, and the Cochrane Central Register of Controlled Trials for randomized controlled endpoint statin trials...

journal_title：European heart journal

authors： Preiss D,Campbell RT,Murray HM,Ford I,Packard CJ,Sattar N,Rahimi K,Colhoun HM,Waters DD,LaRosa JC,Amarenco P,Pedersen TR,Tikkanen MJ,Koren MJ,Poulter NR,Sever PS,Ridker PM,MacFadyen JG,Solomon SD,Davis BR,Simpson

更新日期：2015-06-21 00:00:00

abstract：AIMS:Hypertrophic cardiomyopathy (HCM) is a disease with marked regional differences in wall thickness. However, the relation between myocardial function and wall thickness has not been well studied. Ultrasonic strain rate (SR) imaging makes it possible to study the regional myocardial deformation. We investigated whet...

journal_title：European heart journal

authors： Ganame J,Mertens L,Eidem BW,Claus P,D'hooge J,Havemann LM,McMahon CJ,Elayda MA,Vaughn WK,Towbin JA,Ayres NA,Pignatelli RH

更新日期：2007-12-01 00:00:00

abstract：AIMS:To test the hypothesis that increasing age in patients presenting with high-risk non-ST-segment elevation acute coronary syndromes (NSTE-ACS) does not adversely influence the benefit of an early invasive strategy on major adverse events at 6 months. METHODS AND RESULTS:We report clinical outcomes in young (<70), ...

journal_title：European heart journal

authors： Devlin G,Gore JM,Elliott J,Wijesinghe N,Eagle KA,Avezum A,Huang W,Brieger D,GRACE Investigators.

更新日期：2008-05-01 00:00:00

abstract：:A 54-year-old man suffering from effort angina pectoris had an anomalous origin of the left anterior descending coronary artery (LAD) from the right sinus of Valsalva (RSV). The anomalous LAD with a small ostium and without other significant narrowing initially ran into the interventricular septum and subsequently the...

journal_title：European heart journal

authors： Takenaka T,Horimoto M,Fujiwara M

更新日期：1993-01-01 00:00:00

abstract：:It was recently shown that streptokinase may induce clot formation in vivo by immunoglobulin G mediated platelet stimulation. We evaluated the in vitro effect of streptokinase on platelet function in 103 subjects, of whom 52 were < or = 30 years and 51 were > or = 50 years old. Although streptokinase inhibited platele...

journal_title：European heart journal

authors： Terres W,Krüger K,Bleifeld W

更新日期：1992-11-01 00:00:00

abstract：:The haemodynamic effects of intravenous frusemide (1 mg/kg) were studied in 22 male patients with left ventricular failure following acute myocardial infarction. Radiographic pulmonary oedema was present in all patients and their average left heart filling pressure was 20 mmHg. Bolus injection of the drug was followed...

journal_title：European heart journal

authors： Nelson GI,Ahuja RC,Silke B,Okoli RC,Hussain M,Taylor SH

更新日期：1983-10-01 00:00:00

abstract：AIMS:Oral glucose-lowering medications are associated with excess risk of heart failure (HF). Given the absence of comparative data among drug classes, we performed a retrospective study in 32 Health Services of 16 Italian regions accounting for a population of 18 million individuals, to assess the association between ...

journal_title：European heart journal

authors： Fadini GP,Avogaro A,Degli Esposti L,Russo P,Saragoni S,Buda S,Rosano G,Pecorelli S,Pani L,OsMed Health-DB Network.

更新日期：2015-09-21 00:00:00