High-sugar feeding and increasing cholesterol levels in infants.

Abstract:

:Hypercholesterolaemia is an important risk factor for cardiovascular disease. Both total and LDL cholesterol levels are three-fold higher at the end of the first year of life and about four-fold higher in adulthood compared with the neonatal period. In the USA, only 25% of infants are exclusively breastfed and simple carbohydrate-rich formulas are preferentially consumed. Spikes in fasting glucose and insulin have been reported in formula-fed infants and are associated with higher levels of proprotein convertase subtilisin/kexin type 9, suggesting a potential link between high simple sugar intake and consequent increase in LDL cholesterol in early childhood.

journal_name

Eur Heart J

journal_title

European heart journal

authors

Zubin Maslov P,Hill JA,Lüscher TF,Narula J

doi

10.1093/eurheartj/ehaa868

subject

Has Abstract

pub_date

2020-12-16 00:00:00

eissn

0195-668X

issn

1522-9645

pii

6039265

pub_type

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