Abstract:
:Abnormalities in eye tracking are consistently observed in schizophrenia patients and their relatives and have been proposed as an endophenotype of the disease. The aim of this study was to investigate the performance of patients at Ultra High Risk (UHR) for developing psychosis on a task of smooth pursuit eye movement (SPEM). Forty-six UHR patients and twenty-eight age and education matched controls were assessed with a task of SPEM and psychiatric questionnaires. Our results showed that both the corrective and non-corrective saccadic rates during pursuit were higher in the UHR group. There were however no differences in smooth pursuit gain between the two groups. The saccadic rate was related to positive UHR symptoms. Our findings indicate that abnormalities in SPEM are already present in UHR patients, prior to a first psychotic episode. These abnormalities occur only in the saccadic system.
journal_name
Brain Cognjournal_title
Brain and cognitionauthors
van Tricht MJ,Nieman DH,Bour LJ,Boerée T,Koelman JH,de Haan L,Linszen DHdoi
10.1016/j.bandc.2010.05.005subject
Has Abstractpub_date
2010-08-01 00:00:00pages
215-21issue
3eissn
0278-2626issn
1090-2147pii
S0278-2626(10)00059-Xjournal_volume
73pub_type
杂志文章abstract::Visual input was lateralized using a specially designed contact lens system. Subjects performed a sequence of two keypresses in response to a light stimulus with either the left or the right hand in a choice reaction time paradigm. Two choice reaction time conditions were used: (A) hand certainty, sequence uncertainty...
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pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 临床试验,杂志文章
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更新日期:2004-12-01 00:00:00
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pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 传,历史文章,杂志文章
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更新日期:2003-02-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.bandc.2016.07.002
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journal_title:Brain and cognition
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journal_title:Brain and cognition
pub_type: 杂志文章,评审
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journal_title:Brain and cognition
pub_type: 临床试验,杂志文章
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更新日期:1998-04-01 00:00:00
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pub_type: 杂志文章
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2008.09.004
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/s0278-2626(01)80075-0
更新日期:2001-06-01 00:00:00
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journal_title:Brain and cognition
pub_type: 临床试验,杂志文章
doi:10.1016/j.bandc.2004.02.024
更新日期:2004-07-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/s0278-2626(03)00122-2
更新日期:2003-11-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/s0278-2626(03)00077-0
更新日期:2003-07-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/S0278-2626(03)00264-1
更新日期:2004-03-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2012.08.005
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pub_type: 杂志文章
doi:10.1016/j.bandc.2014.10.005
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2006.09.005
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2016.02.008
更新日期:2017-03-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.bandc.2011.07.010
更新日期:2011-11-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2009.05.007
更新日期:2009-12-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/0278-2626(90)90026-k
更新日期:1990-11-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/0278-2626(88)90046-2
更新日期:1988-10-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/j.bandc.2020.105584
更新日期:2020-08-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:10.1016/s0278-2626(01)80066-x
更新日期:2001-06-01 00:00:00
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journal_title:Brain and cognition
pub_type: 杂志文章
doi:
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