Increased saccadic rate during smooth pursuit eye movements in patients at Ultra High Risk for developing a psychosis.

Abstract:

:Abnormalities in eye tracking are consistently observed in schizophrenia patients and their relatives and have been proposed as an endophenotype of the disease. The aim of this study was to investigate the performance of patients at Ultra High Risk (UHR) for developing psychosis on a task of smooth pursuit eye movement (SPEM). Forty-six UHR patients and twenty-eight age and education matched controls were assessed with a task of SPEM and psychiatric questionnaires. Our results showed that both the corrective and non-corrective saccadic rates during pursuit were higher in the UHR group. There were however no differences in smooth pursuit gain between the two groups. The saccadic rate was related to positive UHR symptoms. Our findings indicate that abnormalities in SPEM are already present in UHR patients, prior to a first psychotic episode. These abnormalities occur only in the saccadic system.

journal_name

Brain Cogn

journal_title

Brain and cognition

authors

van Tricht MJ,Nieman DH,Bour LJ,Boerée T,Koelman JH,de Haan L,Linszen DH

doi

10.1016/j.bandc.2010.05.005

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

215-21

issue

3

eissn

0278-2626

issn

1090-2147

pii

S0278-2626(10)00059-X

journal_volume

73

pub_type

杂志文章
  • Evidence for cerebral asymmetries in a finger sequencing task.

    abstract::Visual input was lateralized using a specially designed contact lens system. Subjects performed a sequence of two keypresses in response to a light stimulus with either the left or the right hand in a choice reaction time paradigm. Two choice reaction time conditions were used: (A) hand certainty, sequence uncertainty...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/0278-2626(89)90047-x

    authors: Sivak B,MacKenzie CL

    更新日期:1989-01-01 00:00:00

  • Impairment of voice and face recognition in patients with hemispheric damage.

    abstract::Voice and face recognition were tested in 21 left- and 9 right-hemisphere-damaged patients. Test materials were photographs and recordings of famous political and entertainment personalities. Pathological face recognition (prosopagnosia) and voice recognition (phonagnosia) were both significantly more prevalent in the...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/0278-2626(82)90016-1

    authors: Van Lancker DR,Canter GJ

    更新日期:1982-04-01 00:00:00

  • Inconsistency in serial choice decision and motor reaction times dissociate in younger and older adults.

    abstract::Intraindividual variability (inconsistency) in reaction time (RT) latencies was investigated in a group of younger (M=25.46 years) and older (M=69.29 years) men. Both groups performed 300 trials in 2-, 4-, and 8-choice RT conditions where RTs for decision and motor components of the task were recorded separately. A di...

    journal_title:Brain and cognition

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.bandc.2004.08.006

    authors: Bunce D,MacDonald SW,Hultsch DF

    更新日期:2004-12-01 00:00:00

  • What hemodynamic (fNIRS), electrophysiological (EEG) and autonomic integrated measures can tell us about emotional processing.

    abstract::Due to its fast temporal evolution and its representation and integration among complex and widespread neural networks, the emotion perception process should preferably be examined by means of multimethodological approach. Indeed the indubitable vantage of acquiring both the autonomic (arousal-related) and the central...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2015.02.001

    authors: Balconi M,Grippa E,Vanutelli ME

    更新日期:2015-04-01 00:00:00

  • The vibrating nerve impulse in Newton, Willis and Gassendi: first steps in a mechanical theory of communication.

    abstract::In later editions of his two major works, Isaac Newton proposed an electrical hypothesis of nervous transmission. According to this hypothesis, an electrical aether permeates the nerve and transmits vibrations along it. This implies that the nerve is a communication line, and potentially, an extension of the mind. The...

    journal_title:Brain and cognition

    pub_type: 传,历史文章,杂志文章

    doi:10.1016/s0278-2626(02)00513-4

    authors: Wallace W

    更新日期:2003-02-01 00:00:00

  • Encoding-retrieval interactions in mild Alzheimer's disease: the role of access to categorical information.

    abstract::Normal old adults and patients in an early phase of Alzheimer's disease (AD) were presented with photographs of common objects under two different encoding conditions: naming and naming along with category decisions. Memory was assessed with free recall, category cued recall, and recognition. For both groups, recognit...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1006/brcg.1997.0916

    authors: Lipinska B,Bäckman L

    更新日期:1997-07-01 00:00:00

  • An introduction to magnetoencephalography with some applications.

    abstract::In this paper an attempt was made to describe the basic principles and procedures involved in recording, noninvasively, magnetic fields from the surface of the head and estimating the intracranial sources that give rise to these fields, presumably the same ones that result in time-varying voltages in the scalp that ar...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1006/brcg.1995.1026

    authors: Papanicolaou AC

    更新日期:1995-04-01 00:00:00

  • Shifting ear differences in melody recognition through strategy inducement.

    abstract::In a previous study, the pattern of ear superiority displayed by nonmusicians in a task where dichotically presented target melodies have to be recognized among four probes was found to be correlated with subjects' descriptions of their operating modes: those who reported focusing on critical local differences in pitc...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/0278-2626(87)90121-7

    authors: Peretz I,Morais J,Bertelson P

    更新日期:1987-04-01 00:00:00

  • Hemispheric modulations of the attentional networks.

    abstract::Although several recent studies investigated the hemispheric contributions to the attentional networks using the Attention Network Test (ANT), the role of the cerebral hemispheres in modulating the interaction among them remains unclear. In this study, two lateralized versions of this test (LANT) were used to investig...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2016.07.002

    authors: Spagna A,Martella D,Fuentes LJ,Marotta A,Casagrande M

    更新日期:2016-10-01 00:00:00

  • Age of acquisition and name agreement as predictors of mean response latencies in picture naming of French adults.

    abstract::We studied the influence of five variables on picture naming latencies in French adult subjects: frequency, age of acquisition and length of words, name agreement in oral naming, and visual complexity of pictures. 140 pictures were presented to 56 subjects with control of individual factors (age, educational level, ge...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:

    authors: Kremin H,Hamerel M,Dordain M,De Wilde M,Perrier D

    更新日期:2000-06-01 00:00:00

  • Demythologizing the emotions: adaptation, cognition, and visceral representations of emotion in the nervous system.

    abstract::This article highlights four issues about the neurobiology of emotions: adaptation vs. dysfunction, peripheral and central representations of emotion, the regulation of the internal milieu, and whether emotions are cognitive. It is argued that the emotions evolved to play diverse adaptive roles and are biologically vi...

    journal_title:Brain and cognition

    pub_type: 杂志文章,评审

    doi:10.1016/s0278-2626(03)00004-6

    authors: Schulkin J,Thompson BL,Rosen JB

    更新日期:2003-06-01 00:00:00

  • The representation of arithmetic facts in memory: results from retraining a brain-damaged patient.

    abstract::This single case study was designed to gather evidence regarding whether the mental representations mediating multiplication fact retrieval make use of single or multiple codes. MC is a brain-damaged volunteer whose numerical processing impairments were limited to multiplication fact retrieval. He relearned three sets...

    journal_title:Brain and cognition

    pub_type: 临床试验,杂志文章

    doi:10.1006/brcg.1998.0997

    authors: Whetstone T

    更新日期:1998-04-01 00:00:00

  • Cue utilization following different forms of encoding in mildly, moderately, and severely demented patients with Alzheimer's disease.

    abstract::The ability of patients with Alzheimer's disease (AD) to utilize semantic category cues in order to improve memory performance was examined. Categorizable lists of words or objects were presented under five different encoding conditions: (a) nouns, (b) objects, (c) objects with a semantic orienting question, (d) objec...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/0278-2626(91)90020-9

    authors: Herlitz A,Adolfsson R,Bäckman L,Nilsson LG

    更新日期:1991-01-01 00:00:00

  • Sex differences in parietal lobe morphology: relationship to mental rotation performance.

    abstract::Structural magnetic resonance imaging (MRI) studies of the human brain have reported evidence for sexual dimorphism. In addition to sex differences in overall cerebral volume, differences in the proportion of gray matter (GM) to white matter (WM) volume have been observed, particularly in the parietal lobe. To our kno...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2008.09.004

    authors: Koscik T,O'Leary D,Moser DJ,Andreasen NC,Nopoulos P

    更新日期:2009-04-01 00:00:00

  • Brain and face: communicating signals of health in the left and right sides of the face.

    abstract::In human communication and mate selection the appearance of health sends signals regarding biological fitness. We compared the appearance of health in the sides of the face to previous results on left-right facial asymmetry in the appearance of beauty (1). The stimuli were created by aligning the left and right sides ...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/s0278-2626(01)80075-0

    authors: Reis VA,Zaidel DW

    更新日期:2001-06-01 00:00:00

  • Priming of non-speech vocalizations in male adults: the influence of the speaker's gender.

    abstract::Previous research reported a priming effect for voices. However, the type of information primed is still largely unknown. In this study, we examined the influence of speaker's gender and emotional category of the stimulus on priming of non-speech vocalizations in 10 male participants, who performed a gender identifica...

    journal_title:Brain and cognition

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.bandc.2004.02.024

    authors: Fecteau S,Armony JL,Joanette Y,Belin P

    更新日期:2004-07-01 00:00:00

  • Productivity of lexical categories in French-speaking children with cochlear implants.

    abstract::The productivity of lexical categories was studied longitudinally in a sample of 17 young hearing-impaired French-speaking children with cochlear implants. Age of implantation ranged from 22 months to 76 months. Spontaneous speech samples were collected at six-month intervals over a period of 36 months, starting at th...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/s0278-2626(03)00122-2

    authors: Le Normand MT,Ouellet C,Cohen H

    更新日期:2003-11-01 00:00:00

  • A high density ERP comparison of mental rotation and mental size transformation.

    abstract::To compare mental rotation and mental size transformation, 128-channel EEG was recorded while subjects performed both tasks using random two-dimensional shapes as stimuli. Behavioural results showed significant linear effects of both size transformation and mental rotation on reaction times. Rotation ERPs showed exper...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/s0278-2626(03)00077-0

    authors: Muthukumaraswamy SD,Johnson BW,Hamm JP

    更新日期:2003-07-01 00:00:00

  • Effect of musical expertise on visuospatial abilities: evidence from reaction times and mental imagery.

    abstract::Recently, the relationship between music and nonmusical cognitive abilities has been highly debated. It has been documented that formal music training would improve verbal, mathematical or visuospatial performance in children. In the experiments described here, we tested if visual perception and imagery abilities were...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/S0278-2626(03)00264-1

    authors: Brochard R,Dufour A,Després O

    更新日期:2004-03-01 00:00:00

  • Hemispheric asymmetries in meaning selection: evidence from the disambiguation of homophonic vs. heterophonic homographs.

    abstract::Research investigating hemispheric asymmetries in meaning selection using homophonic homographs (e.g., bank), suggests that the left hemisphere (LH) quickly selects contextually relevant meanings, whereas the right hemisphere (RH) maintains a broader spectrum of meanings including those that are contextually irrelevan...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2012.08.005

    authors: Peleg O,Markus A,Eviatar Z

    更新日期:2012-12-01 00:00:00

  • Responsiveness and functional connectivity of the scene-sensitive retrosplenial complex in 7-11-year-old children.

    abstract::Brain imaging studies have identified two cortical areas, the parahippocampal place area (PPA) and the retrosplenial complex (RSC), that respond preferentially to the viewing of scenes. Contrary to the PPA, little is known about the functional maturation and cognitive control of the RSC. Here we used functional magnet...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2014.10.005

    authors: Jiang P,Tokariev M,Aronen ET,Salonen O,Ma Y,Vuontela V,Carlson S

    更新日期:2014-12-01 00:00:00

  • Methodological issues in measures of imitative reaction times.

    abstract::Ideomotor (IM) theory suggests that observing someone else perform an action activates an internal motor representation of that behaviour within the observer. Evidence supporting the case for an ideomotor theory of imitation has come from studies that show imitative responses to be faster than the same behavioural mea...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2006.09.005

    authors: Aicken MD,Wilson AD,Williams JH,Mon-Williams M

    更新日期:2007-04-01 00:00:00

  • To be precise, the details don't matter: On predictive processing, precision, and level of detail of predictions.

    abstract::Many theoretical and empirical contributions to the Predictive Processing account emphasize the important role of precision modulation of prediction errors. Recently it has been proposed that the causal models used in human predictive processing are best formally modeled by categorical probability distributions. Cruci...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2016.02.008

    authors: Kwisthout J,Bekkering H,van Rooij I

    更新日期:2017-03-01 00:00:00

  • Transfer of short-term motor learning across the lower limbs as a function of task conception and practice order.

    abstract::Interlimb transfer of motor learning, indicating an improvement in performance with one limb following training with the other, often occurs asymmetrically (i.e., from non-dominant to dominant limb or vice versa, but not both). In the present study, we examined whether interlimb transfer of the same motor task could o...

    journal_title:Brain and cognition

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.bandc.2011.07.010

    authors: Stöckel T,Wang J

    更新日期:2011-11-01 00:00:00

  • Distinct brain systems underlie the processing of valence and arousal of affective pictures.

    abstract::Valence and arousal are thought to be the primary dimensions of human emotion. However, the degree to which valence and arousal interact in determining brain responses to emotional pictures is still elusive. This functional MRI study aimed to delineate neural systems responding to valence and arousal, and their intera...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2009.05.007

    authors: Nielen MM,Heslenfeld DJ,Heinen K,Van Strien JW,Witter MP,Jonker C,Veltman DJ

    更新日期:2009-12-01 00:00:00

  • Psychology of time awareness.

    abstract::Mind transforms the continuance of physical space-time into moments (the absolute Now) and blends these moments into an apparent continuity through an overlapping of unfolding capsules. The flow of psychological time is an illusion based on the rapid replacement of these capsules. Each mind computes the measure of tim...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/0278-2626(90)90026-k

    authors: Brown JW

    更新日期:1990-11-01 00:00:00

  • A case study of mental imagery deficit.

    abstract::We describe a patient with a deficit in imagery ability, following a left posterior cerebral artery infarction and possible anoxic episode. This deficit was inferred from the patient's performance on several tasks, including one in which normal adults are known to rely on imagery and two that tested imagery nonverball...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/0278-2626(88)90046-2

    authors: Farah MJ,Levine DN,Calvanio R

    更新日期:1988-10-01 00:00:00

  • Semantic and attentional networks in bilingual processing: fMRI connectivity signatures of translation directionality.

    abstract::Comparisons between backward and forward translation (BT, FT) have long illuminated the organization of bilingual memory, with neuroscientific evidence indicating that FT would involve greater linguistic and attentional demands. However, no study has directly assessed the functional interaction between relevant mechan...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/j.bandc.2020.105584

    authors: Zheng B,Báez S,Su L,Xiang X,Weis S,Ibáñez A,García AM

    更新日期:2020-08-01 00:00:00

  • Semantic information is used by a deep dyslexic to parse compounds.

    abstract::We report a case study of a 48 year-old patient, J.O., who was tested 20 years after the removal of a tumor in the left temporal-parietal region. This surgery and subsequent radiation resulted in right side paralysis and numerous language problems. Tests of J.O.'s single word reading abilities indicate that she could ...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:10.1016/s0278-2626(01)80066-x

    authors: McEwen S,Westbury C,Buchanan L,Libben G

    更新日期:2001-06-01 00:00:00

  • Text structure and content modulate the recall of patients with dementia of the Alzheimer's type.

    abstract::Two descriptive and two narrative texts were constructed. The basic forms of each type of text comprised 27 micropropositions, while the detailed forms incorporated an additional 24 micropropositions. Forty DAT patients and 14 control subjects were asked to read and recall the 4 texts and the total number of microprop...

    journal_title:Brain and cognition

    pub_type: 杂志文章

    doi:

    authors: Gély-Nargeot MC,Ska B,Touchon J

    更新日期:2002-03-01 00:00:00