Abstract：
:In the present work we genotyped three single-nucleotide polymorphisms (SNPs) (rs7301328, rs1805247, and rs1805502) of the GRIN2B gene in a set of 480 unrelated bipolar disorder patients and 480 unrelated genetically matched normal controls in Chinese Han population by either allelic-specific multiplex ligation-detection reaction (AMLR) technology or direct sequencing. Rs1805247 and the haplotype consisting of rs1805502 and rs1805247 were significantly associated, suggesting GRIN2B as having a role in the etiology of bipolar disorder.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Zhao Q,Che R,Zhang Z,Wang P,Li J,Li Y,Huang K,Tang W,Feng G,Lindpaintner K,He L,Shi Ydoi
10.1016/j.psychres.2009.11.026subject
Has Abstractpub_date
2011-01-30 00:00:00pages
290-2issue
1-2eissn
0165-1781issn
1872-7123pii
S0165-1781(09)00442-9journal_volume
185pub_type
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