Skin conductance and memory fragmentation after exposure to an emotional film clip in depersonalization disorder.

Abstract:

:It is often assumed that when confronted with an emotional event, patients with DPD inhibit information processing. It is also thought that this fosters memory fragmentation. This hypothesis has not been tested in chronic depersonalization. The aim of this study was to investigate the temporal pattern of autonomic responding to emotional material in depersonalization disorder, along with concomitant deficits in subjective and objective memory formation (i.e., difficulties to form a coherent narrative consisting of an ordered sequence of events). Participants with depersonalization disorder (n=14) and healthy control participants (n=14) viewed an emotional video clip while their skin conductance (SC) levels were measured. Peritraumatic dissociation was measured before and after the clip, and memory performance was measured 35 min after viewing. Compared to controls, depersonalized participants exhibited a distinctly different temporal pattern of autonomic responding, characterized by an earlier peak and subsequent flattening of SCLs. Maximum SCLs did not differ between the two groups. Moreover, unlike the control group, depersonalized participants showed no SC recovery after clip offset. In terms of memory performance, patients exhibited objective memory fragmentation, which they also reported subjectively. However, they did not differ from controls in free recall performance. Apparently, emotional responding in DPD is characterized by a shortened latency to peak with subsequent flattening and is accompanied by memory fragmentation in the light of otherwise unremarkable memory functioning.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Giesbrecht T,Merckelbach H,van Oorsouw K,Simeon D

doi

10.1016/j.psychres.2010.03.010

subject

Has Abstract

pub_date

2010-05-30 00:00:00

pages

342-9

issue

3

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(10)00107-1

journal_volume

177

pub_type

杂志文章
  • Pregnancy, delivery and postpartum in women with schizophrenia or schizoaffective disorder in Finland: a national register-based comparative study.

    abstract::As part of anational Finnish study on reproductive health of women with severe mental disorders, we compared pregnancy- and delivery-, and postpartum-related outcomes between women with schizophrenia (n = 3444) and those with schizoaffective disorder (n = 985), focusing on their singleton pregnancies after illness ons...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.113504

    authors: Simoila L,Isometsä E,Gissler M,Suvisaari J,Sailas E,Halmesmäki E,Lindberg N

    更新日期:2020-12-01 00:00:00

  • No association between chromosome-18 markers and lithium-responsive affective disorders.

    abstract::An allelic association study of excellent responders to lithium was conducted with a candidate gene (Golf, a G-protein receptor gene) and five other chromosome-18p markers. Golf is of special interest because it maps to a region of chromosome 18 where two independent groups (Berrettini et al., 1994; Stine et al., 1995...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(96)02864-8

    authors: Turecki G,Alda M,Grof P,Martin R,Cavazzoni PA,Duffy A,Maciel P,Rouleau GA

    更新日期:1996-06-26 00:00:00

  • The effect of chronic physical illnesses on psychiatric hospital admission in patients with recurrent major depression.

    abstract::People with major depressive disorder (MDD) have an increased burden of chronic physical illnesses (CPI). However, information about the effect of CPIs on recurrent MDD treatment outcome is limited. The objective of this study was to explore whether the number of CPIs in patients with recurrent MDD was associated with...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.12.178

    authors: Šimunović Filipčić I,Filipčić I,Glamuzina L,Devčić S,Bajić Ž,Braš M,Mihaljević Peleš A,Marčinko D,Sartorius N

    更新日期:2019-02-01 00:00:00

  • Does specialization of treatment influence mortality in eating disorders?--A comparison of two retrospective cohorts.

    abstract::Eating disorders (EDs) are psychiatric disorders associated with high morbidity and mortality. It is well established that patients with anorexia nervosa (AN) have an increased risk of premature death, whereas mortality data are lacking for the other EDs. This study aimed to establish mortality rates in a sample of ED...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2015.08.032

    authors: Winkler LA,Bilenberg N,Hørder K,Støving RK

    更新日期:2015-12-15 00:00:00

  • Neurocognitive abilities for a clinically depressed sample versus a matched control group of normal individuals.

    abstract::Depressed patients have been reported to show deficits in tasks that demand memory, planning/sequencing, speeded responding, and effortful responding. Many studies of depressed patients have used inadequate instrumentation or poor control groups. In this investigation, the cognitive performance of 44 patients diagnose...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(94)90011-6

    authors: Grossman I,Kaufman AS,Mednitsky S,Scharff L,Dennis B

    更新日期:1994-03-01 00:00:00

  • Decreased urinary peptide excretion in schizophrenic patients after neuroleptic treatment.

    abstract::Six schizophrenic patients had their urinary peptide levels measured before and after 5 weeks of treatment with neuroleptic medications. For two patients, levels were also measured after a reduction in the neuroleptic dose. Because of the heterogeneity of peptide peaks with the same bioactivity, the overall peptide le...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(95)02629-b

    authors: Reichelt KL,Teigland-Gjerstad B

    更新日期:1995-09-29 00:00:00

  • Psychosis, lithium-induced antipsychotic response, and seasonality.

    abstract::Lithium alone has previously been shown to effect antipsychotic response in approximately one-quarter of mood incongruent psychoses. Such lithium-responsive psychoses and/or the antipsychotic effects of lithium appear to be seasonal, with maximal response rates occurring in the 3-month periods surrounding January and ...

    journal_title:Psychiatry research

    pub_type: 临床试验,杂志文章

    doi:10.1016/0165-1781(88)90122-9

    authors: Garver DL,Hutchinson LJ

    更新日期:1988-12-01 00:00:00

  • A randomized trial of low-dose gabapentin for post hospitalization relapse prevention in a Thai clinical sample of alcohol dependence.

    abstract::Pharmacological treatments for alcohol use disorder show a modest effect, and they are unavailable in certain countries. The study's aim is to investigate the effects of gabapentin on alcohol drinking. One hundred twelve Thai individuals with alcohol dependence and very high alcohol consumption were randomly assigned ...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2018.09.002

    authors: Chompookham P,Rukngan W,Nilaban S,Suwanmajo S,Yoosom P,Kalayasiri R

    更新日期:2018-12-01 00:00:00

  • What is the relationship between body mass index and eating disorder symptomatology in professional female fashion models?

    abstract::Low body mass index (BMI<18/18.5) is utilized as a mandated cutoff for professional fashion model employment, based on assumptions that low BMI indicates eating disorder pathology. No previous studies have examined the association between experimenter-measured BMI and eating disorder symptomatology in professional fas...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2020.113358

    authors: Ralph-Nearman C,Yeh HW,Khalsa SS,Feusner JD,Filik R

    更新日期:2020-11-01 00:00:00

  • Associations between cognition and internalizing problems in young adults with early-onset schizophrenia: A 13-year follow-up study.

    abstract::The present follow-up study examines the associations between cognition and parent-rated internalizing problems among adolescents with early-onset schizophrenia (EOS) at baseline (T1) and self-rated internalizing problems 13 years later (T2). Twelve individuals (8 male/4 female) with EOS and 30 healthy controls (16 ma...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2018.04.033

    authors: Strugstad B,Lau B,Glenne Øie M

    更新日期:2018-07-01 00:00:00

  • The association between absent lunula and depression in depressive outpatients: a case-control study.

    abstract::Absent lunula can progressively develop in a person who previously had a normal-sized lunula and can be associated with various systemic disorders. In this case-control study we hypothesised that absent lunula is associated with depression. The study comprised 332 depressive outpatients as well as 367 age- and sex-mat...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2012.08.011

    authors: Zhou H,Zhao Y,Yu X,Chen S,Chen D,Wang W,Wang Z,Wu X,Zhang Z

    更新日期:2013-01-30 00:00:00

  • Stress reactivity links childhood trauma exposure to an admixture of depressive, anxiety, and psychosis symptoms.

    abstract::Childhood trauma exposure has been associated with a clinically relevant mixed phenotype of psychopathology composed of depressive, anxiety, and psychosis symptoms, across healthy and clinical samples. Altered stress-reactivity after exposure to childhood trauma may be a plausible underlying mechanism explaining this ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.12.012

    authors: van Nierop M,Lecei A,Myin-Germeys I,Collip D,Viechtbauer W,Jacobs N,Derom C,Thiery E,van Os J,van Winkel R

    更新日期:2018-02-01 00:00:00

  • Neuroleptic-induced defecation in rats as a model for neuroleptic dysphoria.

    abstract::Two groups of 32 rats were challenged in a well-habituated environment with haloperidol (0.5 mg/kg), haloperidol (0.1 mg/kg), domperidone (0.1 mg/kg), or saline to study the effect of these drugs on defecation--an index of emotionality--and voluntary movements in the 2 hours after the injection. The haloperidol-treate...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(93)90053-j

    authors: Sachdev P,Loneragan C,Westbrook F

    更新日期:1993-04-01 00:00:00

  • Standardization of Brief Inventory of Social Support Exchange Network (BISSEN) in Japan.

    abstract::This study describes the Brief Inventory of Social Support Exchange Network (BISSEN) as a standardized brief inventory measuring various aspects of social support. We confirmed the reliability and validity for function and direction of support and standardized the BISSEN. For Sample 1, a stratified random sampling met...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.03.056

    authors: Aiba M,Tachikawa H,Fukuoka Y,Lebowitz A,Shiratori Y,Doi N,Matsui Y

    更新日期:2017-07-01 00:00:00

  • Impulsivity in depressed children and adolescents: a comparison between behavioral and neuropsychological data.

    abstract::Impulsivity at the neuropsychological and behavioral levels was investigated in a sample of drug-naive depressed children and adolescents. The performance of 21 patients with a current diagnosis of mood disorder was compared with that of 21 normal controls on tests of executive functions related to impulsivity (Matchi...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2004.12.012

    authors: Cataldo MG,Nobile M,Lorusso ML,Battaglia M,Molteni M

    更新日期:2005-09-15 00:00:00

  • Lithium-responsive affective disorders: no association with the tyrosine hydroxylase gene.

    abstract::Family, adoption, and twin studies have demonstrated the involvement of genetic factors in the etiology of major affective disorders. In an attempt to identify the involved genes, several linkage and association studies have focused on the gene coding for tyrosine hydroxylase, the rate-limiting enzyme in catecholamine...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(96)02888-0

    authors: Cavazzoni P,Alda M,Turecki G,Rouleau G,Grof E,Martin R,Duffy A,Grof P

    更新日期:1996-09-27 00:00:00

  • Indices of noradrenergic output in depression.

    abstract::Concentrations of plasma norepinephrine (NE) and plasma-3-methoxy-4-hydroxyphenylglycol (MHPG), blood pressure, and heart rate were measured on 2 days in 25 depressed patients and 25 controls. Comparisons were made between patients and controls, and also between days for both groups, to determine the short-term stabil...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(86)90093-4

    authors: Siever LJ,Uhde TW,Jimerson DC,Lake CR,Kopin IJ,Murphy DL

    更新日期:1986-09-01 00:00:00

  • Predicting dementia development in Parkinson's disease using Bayesian network classifiers.

    abstract::Parkinson's disease (PD) has broadly been associated with mild cognitive impairment (PDMCI) and dementia (PDD). Researchers have studied surrogate, neuroanatomic biomarkers provided by magnetic resonance imaging (MRI) that may help in the early diagnosis of this condition. In this article, four classification models (...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2012.06.001

    authors: Morales DA,Vives-Gilabert Y,Gómez-Ansón B,Bengoetxea E,Larrañaga P,Bielza C,Pagonabarraga J,Kulisevsky J,Corcuera-Solano I,Delfino M

    更新日期:2013-08-30 00:00:00

  • Increased sensitivity of the inositol-phospholipid system in neutrophils from patients with acute major depressive episodes.

    abstract::Evidence from in vitro and in vivo studies suggests that the therapeutic and prophylactic effects of lithium in recurrent affective disorders are due to an attenuation of the inositol-phospholipid (IPL) second messenger system. An increased sensitivity of this signal transduction system might therefore constitute a ri...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(96)02913-7

    authors: Bohus M,Förstner U,Kiefer C,Gebicke-Härter P,Timmer J,Spraul G,Wark HJ,Hecht H,Berger M,van Calker D

    更新日期:1996-11-01 00:00:00

  • Lowered omega3 polyunsaturated fatty acids in serum phospholipids and cholesteryl esters of depressed patients.

    abstract::Depression is associated with a lowered degree of esterification of serum cholesterol, an increased C20:4omega6/C20:5omega3 ratio and decreases in omega3 fractions in fatty acids (FAs) or in the red blood cell membrane. The aims of the present study were to examine: (i) serum phospholipid and cholesteryl ester composi...

    journal_title:Psychiatry research

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0165-1781(99)00014-1

    authors: Maes M,Christophe A,Delanghe J,Altamura C,Neels H,Meltzer HY

    更新日期:1999-03-22 00:00:00

  • Brain structure and function correlates of cognitive subtypes in schizophrenia.

    abstract::Stable neuropsychological deficits may provide a reliable basis for identifying etiological subtypes of schizophrenia. The aim of this study was to identify clusters of individuals with schizophrenia based on dimensions of neuropsychological performance, and to characterize their neural correlates. We acquired neurops...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.pscychresns.2015.08.008

    authors: Geisler D,Walton E,Naylor M,Roessner V,Lim KO,Charles Schulz S,Gollub RL,Calhoun VD,Sponheim SR,Ehrlich S

    更新日期:2015-10-30 00:00:00

  • The attention-related somatosensory evoked potential late positive wave in psychiatric patients.

    abstract::Somatosensory evoked potential (SEP) late waves (P400) associated with selective attention were elicited by having subjects count electrical stimuli to one of four randomly stimulated fingers. P400 amplitude was lower in a diagnostically heterogeneous group of 20 psychiatric patients than in 16 nonpatients. Among pati...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(81)90045-7

    authors: Josiassen RC,Shagass C,Roemer RA,Straumanis JJ

    更新日期:1981-10-01 00:00:00

  • Pattern-reversed visual evoked potentials in subtypes of major depression.

    abstract::There are no articles in the international psychiatric literature reporting subclinical visual system disorders in depressed patients, although a disturbance of circadian rhythms is one of the prominent theories of the etiopathogenesis of depression. Fifty patients aged 21-60 years suffering from major depression acco...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(03)00097-0

    authors: Fotiou F,Fountoulakis KN,Iacovides A,Kaprinis G

    更新日期:2003-06-15 00:00:00

  • Treating conduct disorder: An effectiveness and natural language analysis study of a new family-centred intervention program.

    abstract::This paper reports on a new family-centred, feedback-informed intervention focused on evaluating therapeutic outcomes and language changes across treatment for conduct disorder (CD). The study included 26 youth and families from a larger randomised, controlled trial (Ronan et al., in preparation). Outcome measures ref...

    journal_title:Psychiatry research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.psychres.2016.11.035

    authors: Stevens KA,Ronan PK,Davies G

    更新日期:2017-05-01 00:00:00

  • Neuropsychological risk indicators for schizophrenia: a preliminary study of female relatives of schizophrenic and bipolar probands.

    abstract::Evidence of subtle neuropsychological deficits in relatives of schizophrenic probands (REL-SZs) suggests that these are risk indicators for schizophrenia, but little is known about whether neuropsychological performance in REL-SZs differs from that in other groups of relatives. We compared neuropsychological function ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/s0165-1781(98)00042-0

    authors: Kremen WS,Faraone SV,Seidman LJ,Pepple JR,Tsuang MT

    更新日期:1998-07-13 00:00:00

  • Early childhood infections and risk of schizophrenia.

    abstract::The association between early childhood infections and the risk of schizophrenia is not clear, and this study aimed to investigate the association between childhood infections and the risk of schizophrenia in a population-based Australia male cohort. A population-based cohort of males born between 1980 and 1984 in Wes...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2012.06.007

    authors: Liang W,Chikritzhs T

    更新日期:2012-12-30 00:00:00

  • Effect of moderate weight loss on prolactin secretion in normal female volunteers.

    abstract::Sleep-related prolactin secretion and prolactin responses to the infusion of low doses of the dopamine antagonist, metoclopramide, and thyrotropin-releasing hormone were measured in 11 female volunteers before and after undertaking a diet in which they lost a mean of 3.1 kg in weight in 3 weeks. No effect of weight lo...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(89)90030-9

    authors: Anderson IM,Crook WS,Gartside SE,Parry-Billings M,Newsholme EA,Cowen PJ

    更新日期:1989-08-01 00:00:00

  • Early signs of worry: psychosis risk symptom visual distortions are independently associated with suicidal ideation.

    abstract::Previous studies have shown an association between suicidal behavior and schizophrenia. However, little is known about this association in those with psychotic experiences and symptoms that do not meet the criteria for full psychosis. The aim of the study was to investigate how psychosis risk symptoms are associated w...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2014.12.031

    authors: Granö N,Salmijärvi L,Karjalainen M,Kallionpää S,Roine M,Taylor P

    更新日期:2015-02-28 00:00:00

  • Caffeine taste test for panic disorder: adenosine receptor supersensitivity.

    abstract::The present study introduces a novel measure of adenosine receptor sensitivity that is based on the action of specific receptor blockers (e.g., caffeine) to potentiate the ability to detect threshold quinine concentrations. The test is used to compare gustatory adenosinergic responses to caffeine challenges in normal ...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/0165-1781(89)90014-0

    authors: DeMet E,Stein MK,Tran C,Chicz-DeMet A,Sangdahl C,Nelson J

    更新日期:1989-12-01 00:00:00

  • Maternal distress in late pregnancy alters obstetric outcomes and the expression of genes important for placental glucocorticoid signalling.

    abstract::The experience of maternal distress in pregnancy is often linked with poorer obstetric outcomes for women as well as adverse outcomes for offspring. Alterations in placental glucocorticoid signalling and subsequent increased fetal exposure to cortisol have been suggested to underlie this relationship. In the current s...

    journal_title:Psychiatry research

    pub_type: 杂志文章

    doi:10.1016/j.psychres.2017.05.013

    authors: Togher KL,Treacy E,O'Keeffe GW,Kenny LC

    更新日期:2017-09-01 00:00:00