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Predictors of early versus late timing of pulmonary embolus after traumatic injury.

Abstract：

OBJECTIVE:To identify risk factors predictive of pulmonary embolus (PE) timing after a traumatic injury. METHODS:One hundred eight traumatic injury patients with a confirmed diagnosis of PE were classified as early PE (≤4 days, n = 54) or late PE (>4 days, n = 54). Independent predictors of early versus late PE were identified using multivariate logistic regression. RESULTS:Half the PEs were diagnosed ≤4 days of injury. Only long bone fractures independently predicted early PE (odds ratio 2.8; 95% confidence interval, 1.1-7.1). Severe head injuries were associated with late PE (odds ratio 11.1; 95% confidence interval, 3.9-31). Established risk factors such as age did not affect timing. CONCLUSIONS:Half the PEs were diagnosed ≤4 days after injury. The risk of early PE appeared highest in patients with long bone fractures, and the benefits of immediate prophylaxis may outweigh risks. Patients with severe head injuries appear to have later PE events. Prospective interventional trials in these injury populations are needed.

journal_name

Am J Surg

journal_title

American journal of surgery

authors

Brakenridge SC,Toomay SM,Sheng JL,Gentilello LM,Shafi S

doi

10.1016/j.amjsurg.2009.12.005

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

209-15

issue

2

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(10)00087-5

journal_volume

201

pub_type

杂志文章

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