Effectiveness of extended lymphadenectomy in noncurative gastrectomy.

Abstract:

PURPOSE:We examined the efficacy of extended lymph node dissection for prolonging survival in macroscopically or histologically proven incurable gastric cancer. PATIENTS AND METHODS:We analyzed clinico-pathologic data on 119 patients with serosally invasive gastric cancer who underwent noncurative gastrectomy, with respect to the relation between the extent of lymphadenectomy and survival benefit. RESULTS:The 5-year survival rate was significantly higher among patients treated with extensive lymphadenectomy (R2/3) compared to simple gastrectomy (R1). Extensive lymphadenectomy significantly prolonged survival time even after noncurative gastrectomy in cases where there was no evidence of hepatic metastasis, peritoneal seeding, or extensive nodal metastasis beyond the tertiary lymph node, and regardless of the extent of direct invasion to adjacent organs. CONCLUSIONS:Gastrectomy combined with extended lymphadenectomy and/or resection of adjacent organs is recommended for gastric cancer patients without distant metastasis, even when the operation is histologically noncurative. Gastrectomy and perioperative intensive chemotherapy are called for when patients have distant metastasis.

journal_name

Am J Surg

authors

Baba H,Maehara Y,Inutsuka S,Takeuchi H,Oshiro T,Adachi Y,Sugimachi K

doi

10.1016/S0002-9610(99)80147-0

subject

Has Abstract

pub_date

1995-02-01 00:00:00

pages

261-4

issue

2

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(99)80147-0

journal_volume

169

pub_type

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