The fate of unscreened women in colon cancer: impact on staging and prognosis.

Abstract:

BACKGROUND:Several nationwide reports show lower female participation in colon cancer screening. We therefore assessed for outcome differences in women of screening age presenting for surgical treatment of colon cancer patients. METHODS:All patients over 50 years undergoing surgery for first-onset colon cancer at Massachusetts General Hospital (2004 to 2011) were included. Differences between (unscreened) women and the remaining population in presentation characteristics and subsequent morbidity and mortality were assessed. RESULTS:We included 919 patients (49.1% female). Women were less often diagnosed through screening (26.4 vs 32.7%, P = .036). Unscreened women were at significantly higher risk (all P < .001) for having high-grade tumors (Relative risk [RR] = 1.61), lymph node metastasis (RR = 1.36), and distant metastasis (RR = 2.26) on pathology, leading to higher colon cancer-related mortality (RR = 1.72). CONCLUSION:Unscreened women present with more advanced colon cancer and higher mortality, confirming that disparities in screening lead to ever-increasing disparities in outcomes.

journal_name

Am J Surg

authors

Amri R,Bordeianou LG,Sylla P,Berger DL

doi

10.1016/j.amjsurg.2014.09.033

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

927-34

issue

6

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(15)00015-X

journal_volume

209

pub_type

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