Feasibility of breast conserving surgery in multifocal breast cancers.

Abstract:

BACKGROUND:Multifocal breast cancers (MFBCs) present a challenge to surgeons. Although its feasibility is still controversial, breast-conserving surgery (BCS) is not contraindicated for MFBCs. The investigators retrospectively evaluated the feasibility of BCS and reviewed histopathologic findings in patients with MFBC. METHODS:A total of 222 patients with MFBC who were treated with either BCS (119 patients) or mastectomy (103 patients) at a single institution between January 2002 and December 2011 were retrospectively evaluated. RESULTS:The median follow-up time was 55 months (range, 10 to 102 months). Lymphovascular invasion and lymph node involvement were significantly less frequent in the BCS group (48.8% vs 62.2% for lymphovascular invasion, P = .04; 52.1% vs 71.8% for lymph node involvement, P = .002). There were no differences in local recurrence rates between the 2 groups. The overall survival rates were 92% in the BCS group and 72% in the mastectomy group (P = .000). CONCLUSIONS:BCS is a feasible and safe procedure for the removal of multifocal tumors. Extended lymphovascular invasion is associated with mortality in patients who undergo mastectomy.

journal_name

Am J Surg

authors

Kadioğlu H,Yücel S,Yildiz S,Bozkurt S,Ersoy YE,Sağlam E,Müslümanoğlu M

doi

10.1016/j.amjsurg.2013.08.008

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

457-64

issue

3

eissn

0002-9610

issn

1879-1883

pii

S0002-9610(13)00451-0

journal_volume

208

pub_type

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