Abstract:
PURPOSE:The purpose of the study was to determine the prognostic significance of the ratio between metastatic and examined lymph nodes to the survival rate of patients with squamous cell carcinoma of the head and neck. MATERIALS AND METHODS:The study included 142 patients in whom metastatic lymph nodes were observed in neck dissection specimens. The number of metastatic lymph nodes and the ratio of metastatic lymph nodes (RMLN) were compared as prognostic factors affecting overall survival (OS) and disease-free survival (DFS) rates. Survival curves were made using Kaplan-Meier analysis and were assessed by the log-rank test and Cox regression method. RESULTS:The median number of metastatic lymph nodes and RMLN for the entire study population were 2 and 4%, respectively. The OS and DFS rates were analyzed in the groups according to such stratification. The result of analysis of OS and DFS showed a statistically significant difference between patients with RMLN of at least 4% and those with RMLN less than 4% (hazard ratio, 3.4 and 2.7; P = .015 and P = .001, respectively). CONCLUSIONS:The ratio of metastatic lymph nodes has a significant impact on the survival period.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Süslü N,Hoşal AS,Sözeri Bdoi
10.1016/j.amjoto.2009.03.004subject
Has Abstractpub_date
2010-09-01 00:00:00pages
315-9issue
5eissn
0196-0709issn
1532-818Xpii
S0196-0709(09)00055-6journal_volume
31pub_type
杂志文章abstract:PURPOSE:The type of allergy and other diagnostic procedures were analyzed in a group of elderly seasonal allergic rhinitis (SAR) patients and were compared with young SAR people and a control group. MATERIALS AND METHODS:Study group consisted of 248 patients with mean age 64.1 ± 4.2 years. They were compared with 289 ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.11.002
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:(1) To detect the presence of residual mesenchyme in temporal bones of adults and children above 5 years of age; (2) to evaluate its regression with increasing age, and; (3) to detect pathologic conditions associated with the presence of unresolved mesenchyme. MATERIALS AND METHODS:We examined 1,404 human temp...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(99)90075-3
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:The receptor activator for nuclear factor-κB ligand (RANKL) and osteoprotegerin (OPG) are the key factors controlling the osteoclast and osteoblast action in the bone. PURPOSE:The study objective was to investigate the expression level of RANKL and OPG in cholesteatoma and granulation tissue, and to assess ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.06.004
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:The standard treatment for patients with early glottic carcinoma in Israel has been radiotherapy. In recent years, encouraging results with laryngo-microscopic carbon dioxide laser surgery as a treatment for early glottic carcinoma has changed our treatment strategy. We conducted a retrospective study to invest...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1053/ajot.2003.2
更新日期:2003-01-01 00:00:00
abstract::Histiocytic necrotizing lymphadenitis (HNL) also known as Kikuchi or Kikuchi-Fujimato disease is a benign and self-limiting disease. The entity was first described in 1972 by Kikuchi and Fujimato in Japan independently. HNL is prevalent in Asia, although it may be seen in a wide geographic distribution. It commonly af...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s0196-0709(03)00061-9
更新日期:2003-09-01 00:00:00
abstract::We report a case of chondrosarcoma of the larynx, diagnosed by a percutaneous core-needle biopsy (CNB). Cartilaginous tumors of the larynx are usually diagnosed by biopsy with direct laryngomicroscopy under general anesthesia. However, patients find it difficult to undergo a biopsy under general anesthesia, for physic...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2014.03.013
更新日期:2014-07-01 00:00:00
abstract::A procedure for laryngotracheal separation was performed on 5 elderly patients in poor general condition to prevent habitual aspiration pneumonia. Intractable aspiration was relieved in all the patients with no major postoperative complications. In this intervention, a modification of the procedure previously reported...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.10.003
更新日期:2011-03-01 00:00:00
abstract::A choristoma is a nonneoplastic proliferation of histologically normal tissue that forms at an abnormal site. It is extremely uncommon in the middle ear space. It appears to be a developmental abnormality and may be associated with abnormalities of adjacent structures. It usually occurs with unilateral conductive hear...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s0196-0709(00)85011-5
更新日期:2000-03-01 00:00:00
abstract::Divided nevus, which is also known as "kissing nevus," "split ocular nevus" and "panda nevus" is a rare congenital dermatological abnormality that occurs on opposing margins of upper and lower eyelids. There is a paucity of literature on this rare anomaly, with most knowledge from this disease process derived from iso...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2013.01.004
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:The most common surgical method to remove benign parotid tumors remains the prograde approach. We examined if a retrograde surgical technique offers better outcomes than historical prograde controls. MATERIALS AND METHODS:A retrospective chart review at Stanford Hospital was conducted to identify retrograde pa...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2017.05.003
更新日期:2017-01-01 00:00:00
abstract::Tuberculosis is known to affect almost every organ in the body, but its manifestations in the head and neck region are quite rare. A tuberculous retropharyngeal abscess is a very rare condition and can be the cause of oropharyngeal dysphagia. It is usually secondary to tuberculosis of the spine and has the potential o...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2011.06.006
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To investigate the correlation between internet search activity and epistaxis-related Emergency Department visits. MATERIALS AND METHODS:Data from Google Trends were obtained (www.google.com/trends) for the search term "nosebleed" in Erie County, Pennsylvania during a five-year period. All epistaxis-related CP...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2018.07.012
更新日期:2018-01-01 00:00:00
abstract::Lightning induced damage to the ear is multifaceted. The seventh and eighth cranial nerves, the labyrinthine system, and the tympanic membrane are most commonly injured. A case report demonstrating all these injuries is presented. ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(80)80036-6
更新日期:1980-08-01 00:00:00
abstract:OBJECTIVE:The objective of the study was to review the diagnosis and treatment of primary immunodeficiency disease (PID) and the role of otolaryngologists in the management of PID. METHODS:A search was conducted of PubMed and the Web sites of organizations for PID patients for literature pertaining to the diagnosis an...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2010.05.001
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to report 2 cases of extramedullary plasmacytoma (EP) with localization to middle ear that were diagnosed and managed in our department. METHODS:The first patient was a 60-year-old man with progressive hearing loss, tinnitus, recurrent episodes of otalgia, and otorrhea in his right e...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.amjoto.2008.07.004
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVES:Studies suggest that hypercholesterolemia promotes the development of inner ear disorders such as tinnitus. However, the underlying pathomechanisms are still not clearly defined. METHODS:A retrospective study was performed to assess whether a reduction of serum cholesterol by 3-hydroxy-3-methylglutaryl coen...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2009.09.004
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To report a single institution's experience using human papillomavirus (HPV) E6/E7 mRNA in-situ hybridization (mRNA ISH) for HPV detection in oropharyngeal squamous cell carcinoma (OPSCC). To review the literature on HPV detection methods. STUDY DESIGN:Retrospective chart review, literature review. SETTING...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102782
更新日期:2021-01-01 00:00:00
abstract::Wegener granulomatosis is an immune-mediated, systemic vasculitis with unknown etiology that can be seen in almost any anatomical site. Positivity for antineutrophil cytoplasmic antigene, which is a serological marker, and presence of granulomatous vasculitis in histopathologic specimens from the lesions are accepted ...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2007.04.007
更新日期:2008-03-01 00:00:00
abstract::Four patients had Eikenella corrodens infections involving the head and neck in different ways. The organism is discussed as a pathogen in mixed infections and as the predominant organism in other processes. As part of the resident microflora of mucous membrane surfaces, it is an important potential pathogen in a numb...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(86)80018-7
更新日期:1986-11-01 00:00:00
abstract:PURPOSE:Few studies in the past decade have focused on antimicrobial resistance of bacteria in pediatric rhinosinusitis. This study aimed to characterize organisms cultured from pediatric chronic rhinosinusitis, as well as current resistance patterns of pathogens. MATERIALS AND METHODS:The study was conducted from Jan...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2008.11.014
更新日期:2010-05-01 00:00:00
abstract::Pharyngocutaneous fistulization is a dreaded and devastating complication of laryngectomy. Although the specific risk factors are controversial, a history of prior radiation therapy has generally been accepted to be a major risk factor for developing this complication. We present a case of a postlaryngectomy pharyngoc...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1053/ajot.2002.126318
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:Evaluate trends in mortality due to acute epiglottitis before and after adoption of Haemophilus influenza Type b vaccination (Hib) in pediatric and adult populations. MATERIALS AND METHODS:Patients who died from acute epiglottis from 1979 to 2017 identified using National Vital Statistics System. Mortality rat...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2020.102882
更新日期:2021-01-04 00:00:00
abstract::We present 3 patients who complained of distorted hearing, tinnitus and otalgia resulting from scalp and facial hair impacting against the tympanic membrane. Removal of the migrated hair with microsuction relieved symptoms immediately. In 2 cases, the patients had presented to the primary care physician earlier, short...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.09.005
更新日期:2014-03-01 00:00:00
abstract:PURPOSE:A case-control study was done to confirm the higher prevalence of sensorineural hearing loss (SNHL) among sickle cell patients (HbSS) from southern Brazil. PATIENTS AND METHODS:Twenty-eight patients and 28 matched normal controls were studied. Besides complete anamneses and physical otolaryngological examinati...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(00)85001-2
更新日期:2000-03-01 00:00:00
abstract:PURPOSE:The purpose to this study is to identify correlations between pathology and dynamic contrast-enhanced magnetic resonance imaging (MRI) and to assess the utility of this technique in the evaluation of radiation response for head and neck cancer. MATERIALS AND METHODS:MRI was prospectively performed after radiot...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2004.11.011
更新日期:2005-05-01 00:00:00
abstract:PURPOSE:To report the result of transcanal tympanoplasty using Lyodura as a graft. MATERIALS AND METHODS:One hundred thirty-seven patients with chronic suppurative otitis media with a dry perforation were considered for tympanoplasty. The transcanal permeatal approach was adopted. Lyodura as a ready-made graft was use...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/s0196-0709(99)90000-5
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:The study objective is to evaluate the clinical features and outcomes of patients treated for head and neck malignant fibrous histiocytoma at a tertiary care medical facility. MATERIALS AND METHODS:This is a retrospective case series of 17 adult subjects with malignant fibrous histiocytoma of the head and neck...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2012.06.010
更新日期:2013-01-01 00:00:00
abstract::The delivery of nutrients to the tissues and the removal of waste products from the tissues is made possible by forcing a stream of blood through an arborizing network of microscopic blood vessels that comprise the microcirculation. The rapidity of the flow stream and, therefore, the rate of nutrient delivery to the t...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,评审
doi:10.1016/s0196-0709(88)80035-8
更新日期:1988-11-01 00:00:00
abstract:PURPOSE:To demonstrate non-inferiority of eberconazole 1% otic solution to clotrimazole 1% solution, and to compare their safety profiles in the treatment of otomycosis. MATERIALS AND METHODS:Multicenter, randomized, double-blind, active treatment-controlled phase 3 clinical trial. One hundred and ninety patients with...
journal_title:American journal of otolaryngology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.amjoto.2018.03.017
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To describe systematic methods developed over 40 years among over 5000 patients at The Taste and Smell Clinic in Washington, DC to evaluate taste and smell dysfunction. MATERIALS AND METHODS:A tripartite methodology was developed. First, methods to determine clinical pathology underlying the multiple disease p...
journal_title:American journal of otolaryngology
pub_type: 杂志文章
doi:10.1016/j.amjoto.2013.04.006
更新日期:2013-09-01 00:00:00