Abstract:
OBJECTIVE:To investigate if oral health parameters were impaired in patients with myocardial infarction (MI) and if there was an association with serum antibody levels against the periodontal pathogens Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa). METHODS:A case-control study consisting of 100 patients with MI and 100 age- and sex-matched controls from the same geographic area was investigated regarding oral health. RESULTS:The MI group had significantly more periodontal bone loss (PBL), number of deepened pockets (NDP), and bleeding on probing (BOP), and lower number of teeth (NT) than the controls. After adjustment for known cardiovascular risk factors NT, BOP, and NDP still remained significantly related to MI (p=0.014, p=0.02, and p=0.0069, respectively). IgG antibody levels against Pg were higher in subjects with MI (p=0.043), as well as in those with >4 deepened pockets (p=0.05), BOP>20% (p=0.001) and PBL (p=0.0003). However, indicating a causal pathway, the relationship between MI and Pg IgG disappeared when the oral parameters were included in the logistic regression model (p=0.69). No correlation was seen between MI and Aa in the present study. CONCLUSION:Patients with MI had an impaired oral health compared to controls. Furthermore, IgG levels against Pg were related to both MI and oral health, suggesting this pathogen as a possible link between oral health and CVD.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Holmlund A,Hedin M,Pussinen PJ,Lerner UH,Lind Ldoi
10.1016/j.ijcard.2009.10.034subject
Has Abstractpub_date
2011-04-14 00:00:00pages
148-53issue
2eissn
0167-5273issn
1874-1754pii
S0167-5273(09)01537-Xjournal_volume
148pub_type
杂志文章abstract::We have studied, by light and electron microscopy, left ventricular endomyocardial biopsy specimens from 18 African patients (14 men) with idiopathic dilated cardiomyopathy in Nairobi. Nine patients (50%) had evidence of healing myocarditis, that is the presence of a mild inflammatory cell infiltration within the myoc...
journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:1993-09-01 00:00:00
abstract::It has been estimated that 5.1million Americans suffer from heart failure. Cognitive impairment has been described as a consequence of heart failure in numerous studies spanning the last three decades. This systematic review helps differentiate "cognitive impairment" into mild cognitive impairment, dementia, and delir...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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更新日期:2015-01-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.07.274
更新日期:2016-11-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2017.07.003
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Previous studies have stated that atrial fibrillation (AF) is associated with a higher risk of dementia. However, none have examined the competition between death and incident dementia in patients with AF. We evaluated the risk of incident dementia in patients with AF in comparison to people without this arr...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.06.235
更新日期:2016-10-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2006.03.038
更新日期:2007-03-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.08.020
更新日期:2009-02-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.07.015
更新日期:2006-04-28 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.10.102
更新日期:2013-06-05 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2010.02.005
更新日期:2011-06-02 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.05.006
更新日期:2018-08-15 00:00:00
abstract:OBJECTIVES:To evaluate the prevalence of atrial fibrillation (AF) in physical laborers in rural China and identify contributing risk factors. METHODS:A cross-sectional study of 11,956 permanent residents of Liaoning Province in rural China≥35y of age (primarily physical laborers) was conducted between January and Augu...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2014.12.063
更新日期:2015-03-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.06.073
更新日期:2017-12-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.04.189
更新日期:2008-08-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.11.091
更新日期:2007-12-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.12.086
更新日期:2018-05-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(96)02660-5
更新日期:1996-07-05 00:00:00
abstract:BACKGROUND:Patients' understanding of the nature and consequences of atrial fibrillation (AF) and appropriate therapy, is essential to optimize AF management. Currently, no valid instrument exists to measure knowledge in AF patients with a combined focus on disease, symptom recognition and therapy. Since there is a nee...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ijcard.2012.12.047
更新日期:2013-09-30 00:00:00
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journal_title:International journal of cardiology
pub_type: 评论,信件
doi:10.1016/j.ijcard.2008.04.005
更新日期:2009-05-29 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2007.02.030
更新日期:2008-04-25 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.11.104
更新日期:2006-09-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(04)90007-1
更新日期:2004-06-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.12.107
更新日期:2009-05-29 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.06.064
更新日期:2013-03-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2007.03.125
更新日期:2008-05-23 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2008.06.045
更新日期:2009-11-12 00:00:00
abstract:BACKGROUND:Evidence indicated an involvement of afferent nerves in the pathology of acute myocardial infarction. This study was undertaken to clarify the role and mechanisms by which the sensory afferent degeneration exacerbates the myocardial injury in acute myocardial infarction in rats. METHODS:The myocardial injur...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2011.03.025
更新日期:2012-09-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(86)90007-0
更新日期:1986-03-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2020.03.032
更新日期:2020-08-01 00:00:00