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Novel developments in stress cardiomyopathy: From pathophysiology to prognosis.

Abstract：

:Stress cardiomyopathy (SC) is characterized by transient left ventricular (LV) wall motion abnormalities typically involving the apex with preserved basal contractility, chest discomfort, ST-T ischemic changes and elevated cardiac markers with normal or non-flow limiting coronary artery lesions. It represents an important differential diagnosis of Acute Coronary Syndromes caused by atherosclerotic vessel occlusion; most commonly, Tako-tsubo occurs in postmenopausal women after physical or emotional stress. While the exact mechanism of SC remains controversial, various hypotheses have been suggested concerning the vascular, central nervous and endocrine system participation where catecholamines, particularly epinephrine, seem to play a major role. Hormonal, genetic and psychiatric conditions may also define the risk of susceptibility in some groups affected by SC. Long-term survival data are limited with mortality occurring predominantly in the first year after diagnosis usually related to non-cardiac illnesses. Echocardiography promises to become a useful tool to correctly identify SC patients at high risk for complications.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Goico A,Chandrasekaran M,Herrera CJ

doi

10.1016/j.ijcard.2016.08.241

subject

Has Abstract

pub_date

2016-11-15 00:00:00

pages

1053-1058

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(16)31949-0

journal_volume

223

pub_type

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