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Dilated cardiomyopathy and myocarditis in Kenya: an endomyocardial biopsy study.

Abstract：

:We have studied, by light and electron microscopy, left ventricular endomyocardial biopsy specimens from 18 African patients (14 men) with idiopathic dilated cardiomyopathy in Nairobi. Nine patients (50%) had evidence of healing myocarditis, that is the presence of a mild inflammatory cell infiltration within the myocardium. Interstitial fibrosis was prominent in five patients (28%) and in all 18 specimens there were hypertrophied muscle fibres. Therefore, half of the patients with idiopathic dilated cardiomyopathy had histological signs of a previous myocarditis. There was no serological evidence of a previous or recent coxsackie infection or any other common viral infections. It seems probable that the myocarditis was due to an inappropriate immunological reaction to myocardial muscle.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Sanderson JE,Olsen EG,Gatei D

doi

10.1016/0167-5273(93)90156-b

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

157-63

issue

2

eissn

0167-5273

issn

1874-1754

pii

0167-5273(93)90156-B

journal_volume

41

pub_type

杂志文章

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