Abstract:
AIM:We assessed the impact of race on clinical outcome in the multiracial Singapore congestive heart failure (CHF) population. METHODS:668 CHF patients (Age 66+/-12 years, Ejection fraction 29+/-13%), consisting of Chinese (72%), Malays (17.1%) and Indians (10.9%) were prospectively followed up for 24+/-12 months. Primary outcome measure was the composite end-point of all-cause mortality or CHF readmission. RESULTS:Composite end-points occurred in 198 (29.6%) patients (133 deaths, 112 CHF readmissions). Diabetes mellitus (DM), peripheral vascular disease and hyperlipidemia were more prevalent in Indians compared to Malays or Chinese (all p<0.05). Indians and Malays had higher composite end-point rates compared to the Chinese (p=0.01). Although Indians and Malays had higher CHF readmission rates compared to the Chinese (p<0.01), a trend towards a higher all-cause mortality rate was seen in Malays (p=0.12). Malay race was an independent predictor of the composite end-point (OR=1.65, 95% CI=1.04-2.63, p=0.034), as were age, diabetes mellitus, ischemic cardiomyopathy, beta-blocker use, and NYHA class (all p<0.05). CONCLUSIONS:In the multiracial Singapore CHF population, Indians and Malays had a worse outcome compared to the Chinese, due to higher CHF readmission rates in Indians and higher mortality and CHF readmission rates in Malays. While the worse outcome in Indians may be due to the greater prevalence of diabetes mellitus and atherosclerotic vascular disease, the cause of the poorer prognosis in Malays is unclear.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Lee R,Chan SP,Chan YH,Wong J,Lau D,Ng Kdoi
10.1016/j.ijcard.2007.12.107subject
Has Abstractpub_date
2009-05-29 00:00:00pages
422-5issue
3eissn
0167-5273issn
1874-1754pii
S0167-5273(08)00159-9journal_volume
134pub_type
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,评审
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abstract::We have used cross-sectional real time color-coded Doppler echocardiography to characterize the patterns of the regurgitant jet seen in mitral valvar disease of different etiologies. We studied 118 patients with mitral regurgitation due to rheumatic valve disease (n = 26), hypertrophic obstructive cardiomyopathy (n = ...
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
doi:10.1016/j.ijcard.2019.07.092
更新日期:2020-01-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2003.04.022
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abstract:BACKGROUND:The glycoprotein IIb/IIIa antagonists (GPAs) represent a new class of drugs to prevent platelet aggregation in the acute treatment of non-ST-elevation acute coronary syndromes (NSTE-ACS). Systematic reviews have identified serious limitations in published cost-effectiveness analyses, including a lack of UK-s...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2004.08.042
更新日期:2005-04-20 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the prognostic value of myocardial focal fibrosis quantified by late gadolinium enhanced (LGE) magnetic resonance imaging (MRI) in patients with heart failure with preserved ejection fraction (HFpEF). METHODS:One-hundred eleven HFpEF patients (mean age: 70 ± 14 years...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.05.048
更新日期:2015-07-15 00:00:00
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doi:10.1016/0167-5273(93)90108-s
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2005.11.048
更新日期:2006-08-10 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2016.04.027
更新日期:2016-07-15 00:00:00
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更新日期:2014-12-20 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:1989-04-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2007-10-31 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2012.03.065
更新日期:2013-05-25 00:00:00
abstract:BACKGROUND:Perioperative administration of enoximone has been shown to improve hemodynamics, organ function, and inflammatory response. Aim of the present study is to evaluate the impact of enoximone on postoperative renal function after on-pump cardiac surgery. METHODS:A total of 3727 patients undergoing cardiac surg...
journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(94)02225-8
更新日期:1995-02-01 00:00:00
abstract::Left ventricular outflow tract obstruction can occur at the supravalvular, valvular, or subvalvular level. Each level of obstruction is associated with distinct symptomatology, natural history, and operative approach. We describe a case of asymptomatic double site of left ventricular outflow tract obstruction: subvalv...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.08.107
更新日期:2009-03-20 00:00:00