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Evaluation of transient apical ballooning with cardiac magnetic resonance imaging and 31-phosphorous magnetic resonance spectroscopy.

Abstract：

:Apical ballooning is an increasingly reported transient cardiomyopathy with yet unknown origin. In this study 2 cases of apical ballooning are described in whom we used a combined approach of cardiac magnetic resonance imaging (CMR) and 31-Phosphorous magnetic resonance spectroscopy (31P MRS). Electrocardiogram showed ST abnormalities and cardiac serum markers were mildly elevated, but CAG demonstrated smooth coronary arteries. Cine-CMR revealed severe apical akinesia and significantly decreased ejection fraction. Furthermore we detected reduced myocardial phosphocreatine to beta-ATP (PCr/b-ATP) ratios during the first week of acute disease. After 1 week we observed an improvement of PCr/b-ATP ratios by 68% and 34%, which was associated with an increase in left ventricular function. Our data suggest that 31P MRS might be a valuable tool in the evaluation of apical ballooning, but larger cohorts are needed to improve the understanding of metabolic changes during transient apical ballooning.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Klug G,Wolf C,Trieb T,Frick M,Koehler A,Schocke MF,Jaschke W,Pachinger O,Metzler B

doi

10.1016/j.ijcard.2006.06.060

subject

Has Abstract

pub_date

2007-05-31 00:00:00

pages

249-52

issue

2

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(06)00850-3

journal_volume

118

pub_type

信件

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